Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5430Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoTohuku university JapanHuman pancreatic cancer cell lineKLM1NANAWST-1 assay1 MOI60% cell viable after day 2NoNoNA No responseNANANANA27561180
OV_5431Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoTohuku university JapanHuman pancreatic cancer cell lineKLM1NANAWST-1 assay1 MOI10% cell viable after day 4NoNoNA No responseNANANANA27561180
OV_5432Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoTohuku university JapanHuman pancreatic cancer cell lineKLM1NANAWST-1 assay1 MOI100% cell killing after day 6NoNoNA No responseNANANANA27561180
OV_5433Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoTohuku university JapanHuman pancreatic cancer cell lineKLM1NANAWST-1 assay1 MOI100% cell killing after day 8NoNoNA No responseNANANANA27561180
OV_5434Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoTohuku university JapanHuman pancreatic cancer cell lineKLM1NANAWST-1 assay1 MOI100% cell killing after day 10NoNoNA No responseNANANANA27561180