Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1446	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	H322M	NA	NA	XTT assay	Log10 pfu/cell	70% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1458	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.069 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1464	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.092	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1470	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.133	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1476	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.078 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1482	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.081	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1488	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.084	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1494	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1500	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1506	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1512	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1518	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1524	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1530	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1536	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1542	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1548	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1554	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1560	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1566	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1572	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1578	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1584	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1590	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1596	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950