The total number of records retrieved from this search are 38. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_887	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	85% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_890	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	95% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_893	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_896	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_1141	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+5 cells per well	NA	MTT assay	0.01MOI	No cell killing after 3 days	No	No	NA	No response	NA	NA	NA	NA	16278413
OV_1142	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+5 cells per well	NA	MTT assay	0.1MOI	No cell killing after 3 days	No	No	NA	No response	NA	NA	NA	NA	16278413
OV_1143	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+5 cells per well	NA	MTT assay	0.01MOI	70% cell killing after 4 days	No	No	NA	No response	NA	NA	NA	NA	16278413
OV_1144	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+5 cells per well	NA	MTT assay	0.1MOI	70% cell killing after 4 days	No	No	NA	No response	NA	NA	NA	NA	16278413
OV_1260	Adenovirus	AxdAdb-3	DNA	Adenoviridae	Double mutated for E1A and E1B gene	Yes	No	No	ATCC	Prostate cancer cell line	Du145	3.0E+3 cells per well		MTT assay	30 MOI	Surviving cell number reached to 1000	No	No	NA	No response	NA	NA	NA	NA	18063085
OV_2022	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2023	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	1 MOI	100% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2024	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	10 MOI	70% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2025	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	100 MOI	10% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2036	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	0.125 MOI	60% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2037	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	0.25 MOI	45% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2038	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	0.5 MOI	30% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2039	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	1 MOI	20% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2040	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well	NA	MTS assay	2 MOI	20% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2041	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	virus in combination with Docetaxel (7.5)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well		MTS assay	2.15 MOI	70% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2042	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (15 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well		MTS assay	4.3 MOI	50% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2043	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (30 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well		MTS assay	8.6 MOI	30% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2044	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (60 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well		MTS assay	17.2 MOI	10% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_2045	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Virus strain in combination with Docetaxel (120 nM)	No	NA	Human prostate cancer cell line	Du145	7.5E+3 cells per well		MTS assay	34.4 MOI	10% cell survival	No	No	NA	No response	NA	Virus cause increase in apoptosis	NA	NA	21645351
OV_3522	Adenovirus	Adenovirus ZD55	DNA	Adenoviridae	Deletion in E1B55 viral protein	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	1 MOI	95% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3523	Adenovirus	Adenovirus ZD55	DNA	Adenoviridae	Deletion in E1B55 viral protein	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	5 MOI	75% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3524	Adenovirus	Adenovirus ZD55	DNA	Adenoviridae	Deletion in E1B55 viral protein	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	10 MOI	60% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3525	Adenovirus	Adenovirus ZD55	DNA	Adenoviridae	Deletion in E1B55 viral protein	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	20 MOI	50% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3526	Adenovirus	Adenovirus GD55	DNA	Adenoviridae	GOLPH2 regulated aoncolytic adenovirus	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	1 MOI	70% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3527	Adenovirus	Adenovirus GD55	DNA	Adenoviridae	GOLPH2 regulated aoncolytic adenovirus	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	5 MOI	50% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3528	Adenovirus	Adenovirus GD55	DNA	Adenoviridae	GOLPH2 regulated aoncolytic adenovirus	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	10 MOI	40% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3529	Adenovirus	Adenovirus GD55	DNA	Adenoviridae	GOLPH2 regulated aoncolytic adenovirus	Yes	No	No	Shanghai cell collection	Human prostate cancer cell line	Du145	5000 cells per well	NA	MTT assay	20 MOI	20% cell viability	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	28880012
OV_3725	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	Absorbance measurements	0.1 MOI	1% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3732	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	Absorbance measurements	10 MOI	3% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3737	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for Du145 (2.0E+6)	1.0E+7 pfu	NA	Complete regression in tumor after day 80	Intratumoral	NA	NA	NA	29696636
OV_4321	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate carcinoma	Du145	4000 cells per well	NA	MTT assay	10 pfu	91.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5068	Avian orthoreovirus	ARV-PB1	RNA	Reoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	1.0E+3 cells per well	NA	Crystal violet staining	10 MOI	70% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28441762
OV_5622	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human prostate cancer cell line	Du145	80% confluency	NA	MTT assay	31 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5842	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human prostae carcinoma cell line	Du145	80% confluency	NA	NA	31 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578