The total number of records retrieved from this search are 12. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_845	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2780	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_5160	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	40% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5161	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	60% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5162	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5163	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5284	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	0.1 PFU	85% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5285	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	0.33 PFU	70% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5286	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	1 PFU	42% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5287	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	3.3 PFU	10% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5288	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	10 PFU	5% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5289	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	33 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5290	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	A2780	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340