Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 6. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4280AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman bladder transitional cell carcinomaT244000 cells per wellNAMTT assay10 pfu21.1 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4333AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman urinary bladder cancer cell lineT244000 cells per wellNAMTT assay0.001 MOI90% cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4334AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman urinary bladder cancer cell lineT244000 cells per wellNAMTT assay0.01 MOI80% cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4335AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman urinary bladder cancer cell lineT244000 cells per wellNAMTT assay0.1 MOI50% cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4336AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman urinary bladder cancer cell lineT244000 cells per wellNAMTT assay10 MOI38% cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4337AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman urinary bladder cancer cell lineT244000 cells per wellNAMTT assay100 MOI30% cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347