Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 35. Click on ID to see further detail.
IDOV_927Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 virus particle/cellIn-vitro result70% cancer cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_928Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 virus particle/ cellIn-vitro result80% cancer cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_929Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 virus particle/ cellIn-vitro result80% cancer cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_930Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 virus particle/ cellIn-vitro resultAll cancer cell survive after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_959Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 virus particle/cellIn-vitro result90% cancer cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_960Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 virus particle/ cellIn-vitro result90% cancer cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_961Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 virus particle/ cellIn-vitro result60% cancer cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_962Virus nameAdenovirusVirus strainwild typeVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineAlabama-BirminghamOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 virus particle/ cellIn-vitro result20% cancer cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_991Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 pfu/cellIn-vitro result90% cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_992Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 pfu/cellIn-vitro result90% cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_993Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 pfu/cellIn-vitro result80% cell survival after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_994Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 pfu/cellIn-vitro result60% cell kills after 2 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_995Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 pfu/cellIn-vitro result90% cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_996Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 pfu/cellIn-vitro result50% cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_997Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 pfu/cellIn-vitro result20% cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_998Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 pfu/cellIn-vitro result100% cell kills after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_999Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 pfu/cellIn-vitro result60% cell survival after 6 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1000Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 pfu/cellIn-vitro result100% cell kills after 6 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1001Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 pfu/cellIn-vitro result100% cell kills after 6 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1002Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 pfu/cellIn-vitro result100% cell kills after 6 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1003Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 pfu/cellIn-vitro result10% cell kills after 8 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1004Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration100 pfu/cellIn-vitro result100% cell kills after 8 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1005Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration1000 pfu/cellIn-vitro result100% cell kills after 8 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1006Virus nameHerpes simplex virusVirus strainHSV-1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationMutant NV1066Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineMediGene Inc. San Diego, CAOrigin of cell lineNeuroblastoma cell lineCell lineSK-N-SHConcentration of cell line4.0E+3 cells per wellIn-vitro toxicityNAAssayNAIn-vitro virus concentration10000 pfu/cellIn-vitro result100% cell kills after 8 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedApoptosis induction and cspase 3 activationImmunogenic effectNAClinical trialNAPMID15570577
IDOV_1772Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.001 MOIIn-vitro result70% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1773Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.01 MOIIn-vitro result50% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1774Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result40% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1775Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result20% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1776Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration5 MOIIn-vitro result30% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1777Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 MOIIn-vitro result22% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_1778Virus nameParovirusVirus strainH-1PVVirus genome typeDNAVirus familyParoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line7.6E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration50 MOIIn-vitro result20% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedCell cycle arrest at G2 phase and induction of apoptosis by virusImmunogenic effectNAClinical trialNAPMID20087864
IDOV_4205Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineJapanese cancer research resource bankOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration1 MOIIn-vitro result1 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4210Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineJapanese cancer research resource bankOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration0.01 MOIIn-vitro result1 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4211Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineJapanese cancer research resource bankOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration0.1 MOIIn-vitro result1 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4212Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineJapanese cancer research resource bankOrigin of cell lineHuman neuroblastoma cell lineCell lineSK-N-SHConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration1 MOIIn-vitro result1 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056