The total number of records retrieved from this search are 4. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_363	Virus nameHerpes simplex virus	Virus strainSeprehvir (HSV1716)	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationΔγ134.5 attenuated virus mutant	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC or from the Pediatric Preclinical Testing Program (PPTP)	Origin of cell lineHuman neuroblastoma cell line	Cell lineSK-N-BE(2)	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTS cell survival assay	In-vitro virus concentration0.0001 MOI	In-vitro result100% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26583803
IDOV_367	Virus nameHerpes simplex virus	Virus strainSeprehvir (HSV1716)	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationΔγ134.5 attenuated virus mutant	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC or from the Pediatric Preclinical Testing Program (PPTP)	Origin of cell lineHuman neuroblastoma cell line	Cell lineSK-N-BE(2)	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTS cell survival assay	In-vitro virus concentration0.01 MOI	In-vitro result100% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26583803
IDOV_371	Virus nameHerpes simplex virus	Virus strainSeprehvir (HSV1716)	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationΔγ134.5 attenuated virus mutant	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC or from the Pediatric Preclinical Testing Program (PPTP)	Origin of cell lineHuman neuroblastoma cell line	Cell lineSK-N-BE(2)	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTS cell survival assay	In-vitro virus concentration0.1 MOI	In-vitro result58% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26583803
IDOV_375	Virus nameHerpes simplex virus	Virus strainSeprehvir (HSV1716)	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationΔγ134.5 attenuated virus mutant	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC or from the Pediatric Preclinical Testing Program (PPTP)	Origin of cell lineHuman neuroblastoma cell line	Cell lineSK-N-BE(2)	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTS cell survival assay	In-vitro virus concentration1 MOI	In-vitro result18% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26583803