Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_2896Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineLaboratory grown own cultureOrigin of cell lineNeuroblastoma cell line SKNASmCherryFlucCell lineSK-N-ASmCherryFlucConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismCB17 SCID mice xenograft for cell line (5.0E+6)In-vivo virus concentration5.0E+7 pfuIn-vivo toxicityNA In-vivo resultSignificant reduction in tumor volumeMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID23816608