The total number of records retrieved from this search are 16. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_362	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	SK-N-AS	4000 cells per well	NA	MTS cell survival assay	0.0001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_366	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	SK-N-AS	4000 cells per well	NA	MTS cell survival assay	0.01 MOI	76% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_370	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	SK-N-AS	4000 cells per well	NA	MTS cell survival assay	0.1 MOI	26% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_374	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	SK-N-AS	4000 cells per well	NA	MTS cell survival assay	1 MOI	15% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_1744	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	0.001 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1745	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1746	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1747	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	1 MOI	90% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1748	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	5 MOI	60% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1749	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	10 MOI	40% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1750	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	SK-N-AS	7.6E+3 cells per well	NA	MTT assay	50 MOI	20% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_2887	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SK-N-AS	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	70% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2888	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SK-N-AS	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2889	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SK-N-AS	5.0E+3 cells per well	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2890	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SK-N-AS	5.0E+3 cells per well	NA	MTT assay	10 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2896	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line SKNASmCherryFluc	SK-N-ASmCherryFluc	NA	NA	NA	NA	NA	CB17 SCID mice xenograft for cell line (5.0E+6)	5.0E+7 pfu	NA	Significant reduction in tumor volume	NA	NA	NA	NA	23816608