Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 12. Click on ID to see further detail.
IDOV_860Virus nameHerpes simplex virusVirus strainBL1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result94% cancerous cell killing after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_863Virus nameHerpes simplex virusVirus strainBL1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result99% cancerous cell killing after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_866Virus nameHerpes simplex virusVirus strainBL1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result60% cancerous cell killing after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_869Virus nameHerpes simplex virusVirus strainBL1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result95% cancerous cell killing after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_872Virus nameHerpes simplex virusVirus strainJS1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result94% cancerous cell killing after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_875Virus nameHerpes simplex virusVirus strainJS1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result98% cancerous cell killing after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_878Virus nameHerpes simplex virusVirus strainJS1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result60% cancerous cell killing after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_881Virus nameHerpes simplex virusVirus strainJS1Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCellosaurus cell lineCell lineSK-MEL-28Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result95% cancerous cell killing after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID12595888
IDOV_3715Virus nameEnterovirusVirus strainECHO-7 virus stain RigvirVirus genome typeRNAVirus familyPicornaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell linePublic health englandOrigin of cell lineHuman malignant melanoma cell lineCell lineSK-Mel-28Concentration of cell lineNAIn-vitro toxicityNAAssayLive cell imaging systemIn-vitro virus concentration1% virus concentrationIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID29581783
IDOV_3722Virus nameEnterovirusVirus strainECHO-7 virus stain RigvirVirus genome typeRNAVirus familyPicornaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell linePublic health englandOrigin of cell lineHuman malignant melanoma cell lineCell lineSK-Mel-28Concentration of cell lineNAIn-vitro toxicityNAAssayLive cell imaging systemIn-vitro virus concentration10% virus concentrationIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID29581783
IDOV_4374Virus nameNewcastle disease virusVirus strainMTH-68/HVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNCIOrigin of cell lineHuman malignant melanoma cell lineCell lineSK-MEL-28Concentration of cell line500 cells per wellIn-vitro toxicityNAAssayLuciferase based ATP assayIn-vitro virus concentration0.257 MOIIn-vitro result50% cancer cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedER stress and apoptotic pathwayImmunogenic effectIFN production increasedClinical trialNAPMID26408702
IDOV_4387Virus nameNewcastle disease virusVirus strainMTH-68/HVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNCIOrigin of cell lineHuman malignant melanoma cell lineCell lineSK-MEL-28Concentration of cell line500 cells per wellIn-vitro toxicityNAAssayLuciferase based ATP assayIn-vitro virus concentration0.922 MOIIn-vitro result80% cancer cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedER stress and apoptotic pathwayImmunogenic effectIFN production increasedClinical trialNAPMID26408702