Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 52. Click on ID to see further detail.
IDOV_2871Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineLaboratory grown own cultureOrigin of cell lineOsteosarcoma cell lineCell lineORDConcentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.01 MOIIn-vitro result80% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID23816608
IDOV_2872Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineLaboratory grown own cultureOrigin of cell lineOsteosarcoma cell lineCell lineORDConcentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.1 MOIIn-vitro result50% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID23816608
IDOV_2873Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineLaboratory grown own cultureOrigin of cell lineOsteosarcoma cell lineCell lineORDConcentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result30% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID23816608
IDOV_2874Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineLaboratory grown own cultureOrigin of cell lineOsteosarcoma cell lineCell lineORDConcentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 MOIIn-vitro result20% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID23816608
IDOV_3177Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.0001 MOIIn-vitro result60% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3178Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.001 MOIIn-vitro result50% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3179Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.01 MOIIn-vitro result30% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3180Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.1 MOIIn-vitro result30% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3181Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration1 MOIIn-vitro result30% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3182Virus nameHerpes simplex virusVirus strainwild typeVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration10 MOIIn-vitro result30% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3183Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.0001 MOIIn-vitro result75% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3184Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.001 MOIIn-vitro result50% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3185Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.01 MOIIn-vitro result50% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3186Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.1 MOIIn-vitro result40% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3187Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration1 MOIIn-vitro result40% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3188Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration10 MOIIn-vitro result25% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3189Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.0001 MOIIn-vitro result75% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3190Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.001 MOIIn-vitro result50% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3191Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.01 MOIIn-vitro result45% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3192Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.1 MOIIn-vitro result45% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3193Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration1 MOIIn-vitro result40% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3194Virus nameVaccinia virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration10 MOIIn-vitro result45% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3195Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.0001 MOIIn-vitro result55% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3196Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.001 MOIIn-vitro result25% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3197Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.01 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3198Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.1 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3199Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration1 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3200Virus nameVesicular stomatitis virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration10 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3201Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.0001 MOIIn-vitro result20% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3202Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.001 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3203Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.01 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3204Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration0.1 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3205Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration1 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3206Virus nameMaraba virusVirus strainMG1Virus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman edwig sarcoma cell lineCell lineRD-ESConcentration of cell line90% confluenceIn-vitro toxicityNAAssayCrystal violet staining and absorbance at 595 nmIn-vitro virus concentration10 MOIIn-vitro result10% cell survival after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectGenration of memory immune response by incresing production of cytokinesClinical trialNAPMID28568891
IDOV_3710Virus nameEnterovirusVirus strainECHO-7 virus stain RigvirVirus genome typeRNAVirus familyPicornaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell linePublic health englandOrigin of cell lineHuman muscle rhabdomyosarcoma cell lineCell lineRDConcentration of cell lineNAIn-vitro toxicityNAAssayLive cell imaging systemIn-vitro virus concentration1% virus concentrationIn-vitro result94% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID29581783
IDOV_3717Virus nameEnterovirusVirus strainECHO-7 virus stain RigvirVirus genome typeRNAVirus familyPicornaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell linePublic health englandOrigin of cell lineHuman muscle rhabdomyosarcoma cell lineCell lineRDConcentration of cell lineNAIn-vitro toxicityNAAssayLive cell imaging systemIn-vitro virus concentration10% virus concentrationIn-vitro result98% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID29581783
IDOV_5188Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copis of gamma 34.5 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman rhabdosarcoma cell lineCell lineRDConcentration of cell line1.5E+3 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.1 PFUIn-vitro result100% cell viable after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMID27751346
IDOV_5189Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copis of gamma 34.5 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman rhabdosarcoma cell lineCell lineRDConcentration of cell line1.5E+3 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration1 PFUIn-vitro result50% cell viable after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMID27751346
IDOV_5190Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copis of gamma 34.5 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman rhabdosarcoma cell lineCell lineRDConcentration of cell line1.5E+3 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration10 PFUIn-vitro result10% cell viable after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMID27751346
IDOV_5191Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copis of gamma 34.5 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman rhabdosarcoma cell lineCell lineRDConcentration of cell line1.5E+3 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration20 PFUIn-vitro result5% cell viable after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMID27751346
IDOV_5387Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfuIn-vitro result40% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5388Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, one fold dilutionIn-vitro result56.778% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5389Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, two fold dilutionIn-vitro result60.493% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5390Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, three fold dilutionIn-vitro result38.616% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5391Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, four fold dilutionIn-vitro result31.039% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5392Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, five fold dilutionIn-vitro result19.801% cell growth inhibition after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5393Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, one fold dilutionIn-vitro result53.110% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5394Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, two fold dilutionIn-vitro result69.954% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5395Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, three fold dilutionIn-vitro result53.717% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5396Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, four fold dilutionIn-vitro result31.714% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5397Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, five fold dilutionIn-vitro result15.174% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663
IDOV_5398Virus nameMeasles virusVirus strainSchwarz vaccine stainVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineICCMGR cell bank unit, IraqOrigin of cell lineHuman rhabdomyosarcoma cell lineCell lineRDConcentration of cell line7.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3.4 × 10⁵ pfu, six fold dilutionIn-vitro result5.918% cell growth inhibition after 120 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by mitochondrial permeability apoptosis assayImmunogenic effectNAClinical trialNAPMID27512663