Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDOV_5445Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell linePK1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viable after day 2Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5446Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell linePK1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result90% cell viable after day 4Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5447Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell linePK1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viable after day 6Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5448Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell linePK1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result80% cell viable after day 8Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5449Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell linePK1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result60% cell viable after day 10Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180