Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 10. Click on ID to see further detail.
IDOV_5126Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5127Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result80% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5128Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result70% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5129Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result42% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5130Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result30% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5131Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5132Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result82% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5133Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result71% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5134Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result44% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5135Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result30% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889