Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDOV_4246Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNational institute of biomedical innovation, JapanOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H441Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viability after day 1Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4247Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNational institute of biomedical innovation, JapanOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H441Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result80% cell viability after day 3Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4248Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNational institute of biomedical innovation, JapanOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H441Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result35% cell viability after day 5Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4249Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNational institute of biomedical innovation, JapanOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H441Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell killing after day 7Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_5916Virus nameMeasles virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationMutated for SLAM bindingVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman lung cancer cell lineCell lineNCI-H441Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro resultComplete cell killing after 7 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS10335481