Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 6. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4254Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4255Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI55% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4256Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI30% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4257Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI20% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4318AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman nonsmall cell lung cancerNCI-H3584000 cells per wellNAMTT assay10 pfu87.8 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5918Measles viruswild typeRNAParamyxoviridaeMutated for SLAM bindingYesNoNoNAHuman lung cancer cell lineNCI-H358NANAWST-1 assay1 MOI90% cell killing after 7 daysNoNoNA No responseNANANANAUS10335481