Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 6. Click on ID to see further detail.
IDOV_4254Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H358Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viability after day 1Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4255Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H358Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result55% cell viability after day 3Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4256Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H358Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result30% cell viability after day 5Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4257Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineNCI-H358Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result20% cell viability after day 7Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4318Virus nameAlphavirusVirus strainM1Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman nonsmall cell lung cancerCell lineNCI-H358Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 pfuIn-vitro result87.8 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisImmunogenic effectNAClinical trialNAPMID26373347
IDOV_5918Virus nameMeasles virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationMutated for SLAM bindingVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman lung cancer cell lineCell lineNCI-H358Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result90% cell killing after 7 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS10335481