Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 4. Click on ID to see further detail.
IDOV_4442Virus nameHerpes simplex virusVirus strainG47-deltaVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineHuman patientOrigin of cell linemalignant leningiomaCell lineMN3Concentration of cell line4000 to 5000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.03 MOIIn-vitro result78% cell survival after 96 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26951380
IDOV_4443Virus nameHerpes simplex virusVirus strainG47-deltaVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineHuman patientOrigin of cell linemalignant leningiomaCell lineMN3Concentration of cell line4000 to 5000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result18% cell survival after 96 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26951380
IDOV_4444Virus nameHerpes simplex virusVirus strainG47-deltaVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineHuman patientOrigin of cell linemalignant leningiomaCell lineMN3Concentration of cell line4000 to 5000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.3 MOIIn-vitro result1% cell survival after 96 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26951380
IDOV_4445Virus nameHerpes simplex virusVirus strainG47-deltaVirus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineHuman patientOrigin of cell linemalignant leningiomaCell lineMN3Concentration of cell line4000 to 5000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result100% cell killing after 96 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26951380