Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5277Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay0.1 PFU85% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5278Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay0.33 PFU87% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5279Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay1 PFU87% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5280Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay3.3 PFU78% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5281Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay10 PFU62% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5282Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay33 PFU22% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5283Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineMISIIR4000 cells per wellNAAlamar blue assay100 PFU20% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340