The total number of records retrieved from this search are 16. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1924	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viality after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1925	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1926	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1927	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	30% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1936	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viabilty after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1937	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1938	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1939	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_2562	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	88.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2563	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	72.3% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2564	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	58% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2565	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	28% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2566	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	84.3% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2567	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	66.2% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2568	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	54.5% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2569	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	24% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271