The total number of records retrieved from this search are 17. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1151	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	Yes	No	No	ATCC	Colon carcinoma cell line	LoVo	5.0E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	60% cell killing	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_2149	Enterovirus	Enterovirus B species echovirus 12	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	LoVo	NA	NA	Microscopy examination	1 MOI	Partial cell death after 7 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2150	Enterovirus	Enterovirus B species echovirus 15	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	LoVo	NA	NA	Microscopy examination	1 MOI	Partial cell death after 7 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2151	Enterovirus	Enterovirus B species echovirus 17	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	LoVo	NA	NA	Microscopy examination	1 MOI	Partial cell death after 7 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2152	Enterovirus	Enterovirus B species echovirus 26	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	LoVo	NA	NA	Microscopy examination	1 MOI	Partial cell death after 7 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2153	Enterovirus	Enterovirus B species echovirus 29	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	LoVo	NA	NA	Microscopy examination	1 MOI	Partial cell death after 7 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_3048	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3049	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	70% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3050	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	15% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3078	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3079	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	70% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3080	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human colon cancer cell line	LoVo	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	15% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3105	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human colon cancer cell line	LoVo	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 500mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3106	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human colon cancer cell line	LoVo	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to 500mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_4277	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	LoVo	4000 cells per well	NA	MTT assay	10 pfu	6.9 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5896	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene	Yes	No	No	NA	Human colon tumor cell line	LoVo	3.0E+5 pfu	NA	MTT assay	0.00001 MOI	60% of cancer cell death occurs	No	No	NA	No response	NA	NA	NA	NA	US9687515
OV_5897	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in I4L gene	Yes	No	No	NA	Human colon tumor cell line	LoVo	3.0E+5 pfu	NA	MTT assay	0.00001 MOI	58% of cancer cell death occurs	No	No	NA	No response	NA	NA	NA	NA	US9687515