The total number of records retrieved from this search are 14. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_955	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration10 virus particle/cell	In-vitro result70% cancer cell survival after 2 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_956	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration100 virus particle/ cell	In-vitro result75% cancer cell survival after 2 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_957	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration1000 virus particle/ cell	In-vitro result75% cancer cell survival after 2 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_958	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration10000 virus particle/ cell	In-vitro result80% cancer cell survival after 2 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_987	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration10 virus particle/cell	In-vitro result70% cancer cell survival after 4 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_988	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration100 virus particle/ cell	In-vitro result75% cancer cell survival after 4 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_989	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration1000 virus particle/ cell	In-vitro result75% cancer cell survival after 4 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_990	Virus nameAdenovirus	Virus strainwild type	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineAlabama-Birmingham	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration10000 virus particle/ cell	In-vitro result80% cancer cell survival after 4 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_1090	Virus nameHerpes simplex virus	Virus strainHSV-1	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationMutant NV1066	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineMediGene Inc. San Diego, CA	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration1000 pfu/cell	In-vitro result100% cell killing after 8 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_1091	Virus nameHerpes simplex virus	Virus strainHSV-1	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationMutant NV1066	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineMediGene Inc. San Diego, CA	Origin of cell lineNeuroblastoma cell line	Cell lineLan-5	Concentration of cell line4.0E+3 cells per well	In-vitro toxicityNA	AssayNA	In-vitro virus concentration10000 pfu/cell	In-vitro result100% cell killing after 8 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedApoptosis induction and cspase 3 activation	Immunogenic effectNA	Clinical trialNA	PMID15570577
IDOV_4208	Virus nameSindbis virus	Virus strainAR339	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineDr. R.C. Seeger, LA	Origin of cell lineHuman neuroblastoma cell line	Cell lineLan-5	Concentration of cell line1.0E+5 cells per well	In-vitro toxicityNA	AssayLuminiscence measurement	In-vitro virus concentration1 MOI	In-vitro result8 % cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedVirus induce apoptosis process leads to cancer cell death	Immunogenic effectMaximum increased expression of Bcl-2 and Bcl-xL expression	Clinical trialNA	PMID26298056
IDOV_4216	Virus nameSindbis virus	Virus strainAR339	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineDr. R.C. Seeger, LA	Origin of cell lineHuman neuroblastoma cell line	Cell lineLan-5	Concentration of cell line1.0E+5 cells per well	In-vitro toxicityNA	AssayLuminiscence measurement	In-vitro virus concentration0.01 MOI	In-vitro result10 % cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedVirus induce apoptosis process leads to cancer cell death	Immunogenic effectMaximum increased expression of Bcl-2 and Bcl-xL expression	Clinical trialNA	PMID26298056
IDOV_4217	Virus nameSindbis virus	Virus strainAR339	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineDr. R.C. Seeger, LA	Origin of cell lineHuman neuroblastoma cell line	Cell lineLan-5	Concentration of cell line1.0E+5 cells per well	In-vitro toxicityNA	AssayLuminiscence measurement	In-vitro virus concentration0.1 MOI	In-vitro result7 % cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedVirus induce apoptosis process leads to cancer cell death	Immunogenic effectMaximum increased expression of Bcl-2 and Bcl-xL expression	Clinical trialNA	PMID26298056
IDOV_4218	Virus nameSindbis virus	Virus strainAR339	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineDr. R.C. Seeger, LA	Origin of cell lineHuman neuroblastoma cell line	Cell lineLan-5	Concentration of cell line1.0E+5 cells per well	In-vitro toxicityNA	AssayLuminiscence measurement	In-vitro virus concentration1 MOI	In-vitro result6 % cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedVirus induce apoptosis process leads to cancer cell death	Immunogenic effectMaximum increased expression of Bcl-2 and Bcl-xL expression	Clinical trialNA	PMID26298056