Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDOV_5430Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell lineKLM1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result60% cell viable after day 2Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5431Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell lineKLM1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result10% cell viable after day 4Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5432Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell lineKLM1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell killing after day 6Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5433Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell lineKLM1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell killing after day 8Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180
IDOV_5434Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineTohuku university JapanOrigin of cell lineHuman pancreatic cancer cell lineCell lineKLM1Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell killing after day 10Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27561180