Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 3. Click on ID to see further detail.
IDOV_5425Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result70% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5426Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result60% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5427Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result35% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520