The total number of records retrieved from this search are 28. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_951	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_952	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	90% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_953	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_954	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_983	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10 virus particle/cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_984	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_985	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	100% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_986	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1087	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1088	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1089	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	IMR-32	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1751	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	0.001 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1752	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1753	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1754	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	1 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1755	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	5 MOI	100% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1756	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	10 MOI	60% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1757	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	IMR-32	7.6E+3 cells per well	NA	MTT assay	50 MOI	40% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_2883	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	IMR-32	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2884	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	IMR-32	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	42% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2885	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	IMR-32	5.0E+3 cells per well	NA	MTT assay	1 MOI	38% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2886	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	IMR-32	5.0E+3 cells per well	NA	MTT assay	10 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_4206	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	IMR-32	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	3 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4213	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	IMR-32	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4214	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	IMR-32	1.0E+5 cells per well	NA	Luminiscence measurement	0.1 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4215	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	IMR-32	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_5620	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroblastoma cell line	IMR-32	80% confluency	NA	MTT assay	41 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5840	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroblastoma cell line	IMR-32	80% confluency	NA	NA	41 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578