Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1451	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	XTT assay	Log10 pfu/cell	30% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1454	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.144 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1460	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.295	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1466	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.613	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1472	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.178 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1478	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.420	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1484	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.994	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1490	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.352	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1496	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.325	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1502	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.500	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1508	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.053	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1514	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.099	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1520	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.195	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1526	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.372	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1532	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.117	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1538	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.047	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1544	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.099	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1550	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.110	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1556	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.127	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1562	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 1.749	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1568	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 7.049	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1574	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1580	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.133	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1586	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 1.256	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1592	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 11.922	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950