Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_4310Virus nameAlphavirusVirus strainM1Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineSICBOrigin of cell lineHuman nasopharyngeal carcinomaCell lineHNE-1Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 pfuIn-vitro result76.5 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisImmunogenic effectNAClinical trialNAPMID26373347