The total number of records retrieved from this search are 7. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_5298	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5299	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	0.33 PFU	38% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5300	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	1 PFU	10% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5301	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	3.3 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5302	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	10 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5303	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	33 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5304	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	HEYA8 MDR	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340