Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 71. Click on ID to see further detail.
IDOV_4706Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4707Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result98% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4708Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4709Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result75% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4710Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result40% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4721Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4722Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4723Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4724Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result50% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4725Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result25% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4736Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.001 MOIIn-vitro result1% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4737Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4738Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4739Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4740Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4751Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4752Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4753Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result100% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4754Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4763Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result90% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4764Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result90% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4765Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result75% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4766Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result65% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4775Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.01 MOIIn-vitro result25% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4776Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration0.1 MOIIn-vitro result20% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4777Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration1 MOIIn-vitro result15% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4778Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result10% cell survivalModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4787Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4788Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4789Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result18% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4790Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result90% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4791Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result80% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4792Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result10% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4793Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result60% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4794Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result50% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4795Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4796Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result40% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4797Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result20% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4798Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result1% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4799Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result30% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4800Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result2% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4801Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line5000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result2% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4832Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4833Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4834Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result60% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4835Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4836Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result80% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4837Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result10% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4838Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4839Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result70% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4840Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4841Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result90% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4842Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result50% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4843Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result1% cell viability after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4844Virus nameMyxoma virusVirus strainwild typeVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result70% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4845Virus nameVaccinia virusVirus strainvvDDVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion of TK gene and vaccinia growth factorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result20% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_4846Virus nameMaraba virusVirus strainwild typeVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8Concentration of cell line50000 cells per wellIn-vitro toxicityNAAssayCell titer Glo luminiscent assayIn-vitro virus concentration10 MOIIn-vitro result1% cell viability after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID27119108
IDOV_5291Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.1 PFUIn-vitro result100% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5292Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.33 PFUIn-vitro result98% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5293Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration1 PFUIn-vitro result95% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5294Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration3.3 PFUIn-vitro result77% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5295Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration10 PFUIn-vitro result60% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5296Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration33 PFUIn-vitro result39% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5297Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHeyA8Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration100 PFUIn-vitro result22% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5298Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.1 PFUIn-vitro result100% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5299Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.33 PFUIn-vitro result38% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5300Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration1 PFUIn-vitro result10% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5301Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration3.3 PFUIn-vitro result100% cell killingModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5302Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration10 PFUIn-vitro result100% cell killingModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5303Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration33 PFUIn-vitro result100% cell killingModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5304Virus nameHerpes simplex virusVirus strainM032Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineHuman ovarian cancer cell lineCell lineHEYA8 MDRConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration100 PFUIn-vitro result100% cell killingModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340