Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 38. Click on ID to see further detail.
IDOV_887 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDeletion mutant for Gamma 34.5 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining and hematocytometer | In-vitro virus concentration0.1 pfu/ml | In-vitro result85% cncer cell killing after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID12788648 |
IDOV_890 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDeletion mutant for Gamma 34.5 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining and hematocytometer | In-vitro virus concentration0.1 pfu/ml | In-vitro result95% cncer cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID12788648 |
IDOV_893 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDeletion mutant for Gamma 34.5 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining and hematocytometer | In-vitro virus concentration0.01 pfu/ml | In-vitro result80% cncer cell killing after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID12788648 |
IDOV_896 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDeletion mutant for Gamma 34.5 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayTrypan blue staining and hematocytometer | In-vitro virus concentration0.01 pfu/ml | In-vitro result80% cncer cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID12788648 |
IDOV_1141 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01MOI | In-vitro resultNo cell killing after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1142 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1MOI | In-vitro resultNo cell killing after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1143 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01MOI | In-vitro result70% cell killing after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1144 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1MOI | In-vitro result70% cell killing after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1260 | Virus nameAdenovirus | Virus strainAxdAdb-3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDouble mutated for E1A and E1B gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell lineDu145 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicity | AssayMTT assay | In-vitro virus concentration30 MOI | In-vitro resultSurviving cell number reached to 1000 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18063085 |
IDOV_2022 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2023 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2024 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration10 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2025 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration100 MOI | In-vitro result10% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2036 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.125 MOI | In-vitro result60% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2037 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.25 MOI | In-vitro result45% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2038 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.5 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2039 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2040 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration2 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2041 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationvirus in combination with Docetaxel (7.5) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicity | AssayMTS assay | In-vitro virus concentration2.15 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2042 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicity | AssayMTS assay | In-vitro virus concentration4.3 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2043 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (30 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicity | AssayMTS assay | In-vitro virus concentration8.6 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2044 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (60 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicity | AssayMTS assay | In-vitro virus concentration17.2 MOI | In-vitro result10% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2045 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line7.5E+3 cells per well | In-vitro toxicity | AssayMTS assay | In-vitro virus concentration34.4 MOI | In-vitro result10% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_3522 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result95% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3523 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result75% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3524 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3525 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3526 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3527 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3528 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3529 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3725 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration0.1 MOI | In-vitro result1% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3732 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration10 MOI | In-vitro result3% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3737 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c-rag and gamma negative xenograft for Du145 (2.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor after day 80 | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_4321 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate carcinoma | Cell lineDu145 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result91.4 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_5068 | Virus nameAvian orthoreovirus | Virus strainARV-PB1 | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line1.0E+3 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28441762 |
IDOV_5622 | Virus nameNewcastle disease virus | Virus strainNDV-MK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineDu145 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration31 pfu | In-vitro result50% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectInduction of IFN-Gamma production | Clinical trialNA | PMIDUS7470426 |
IDOV_5842 | Virus nameNewcastle disease virus | Virus strainNDV-PPMK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostae carcinoma cell line | Cell lineDu145 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayNA | In-vitro virus concentration31 pfu | In-vitro result50% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS8105578 |