Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 9. Click on ID to see further detail.
IDOV_1109Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration0.01MOIIn-vitro result70% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_1110Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration0.1MOIIn-vitro result50% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_1111Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration1MOIIn-vitro result35% cell viablityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_1124Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration0.01MOIIn-vitro result40% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_1125Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration0.1MOIIn-vitro result25% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_1126Virus nameReovirusVirus strainwild typeVirus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineCervical cancer cell lineCell lineC33AConcentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayFluoroscent mesure at 450nmIn-vitro virus concentration1MOIIn-vitro result5% cell viabilityModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryPathway inducedApoptosis induction in cancer cell linesImmunogenic effectNAClinical trialNAPMID15958641
IDOV_4279Virus nameAlphavirusVirus strainM1Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman cervix carcinomaCell lineC33AConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 pfuIn-vitro result14.8 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisImmunogenic effectNAClinical trialNAPMID26373347
IDOV_4426Virus nameVesicular stomatitis virusVirus strainRdBVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linkerVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman cervical cancer cell lineCell lineC33AConcentration of cell line1.2E+4 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration21:1 particle to pfuIn-vitro result50% cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26430798
IDOV_4434Virus nameVesicular stomatitis virusVirus strainRdB-1L-VSVGVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linkerVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman cervical cancer cell lineCell lineC33AConcentration of cell line1.2E+4 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration24:1 particle to pfuIn-vitro result48% cell survival after 4 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26430798