The total number of records retrieved from this search are 36. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_28	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	80% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_29	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_30	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	40% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_31	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_32	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	82% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_33	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	84% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_34	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	89% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_35	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_36	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_720	Avian influenza A virus	H7N3 NS1-77	RNA	Orthomyxoviridae	Mutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)	Yes	No	No	NA	Human pancreas adenocarcinoma cell line	AsPC-1	NA	NA	Immunoassay detection	0.001 MOI	128% cancer cell death (calculated as relative to mock-infected)	No	No	NA	No response	NA	NA	Up-regulation of IFN-aplha	NA	27417501
OV_724	Avian influenza A virus	H7N3	RNA	Orthomyxoviridae	None	Yes	No	No	NA	Human pancreas adenocarcinoma cell line	AsPC-1	NA	NA	Immunoassay detection	0.001 MOI	165% cancer cell death (calculated as relative to mock-infected)	No	No	NA	No response	NA	NA	Up-regulation of IFN-aplha	NA	27417501
OV_2268	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	1 MOI	5% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2282	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	1 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2296	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	1 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2310	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	1 MOI	80% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2324	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	1 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2338	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2352	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2366	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2380	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2394	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Virus expressing GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	AsPC-1	80% confluent monolayer	NA	MTT assay	0.01 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_3414	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.01 MOI	No cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3415	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.05 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3416	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	75% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3417	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.5 MOI	25% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3418	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	1 MOI	10% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3428	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with gemcitabine (1 × 10⁻¹ micromolar) after 1 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	60% of tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3429	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with gemcitabine (1 × 10⁻¹ micromolar) after 24 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	55% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3436	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 1 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	30% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3437	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 24 hour	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	50% of the tumor cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3452	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.075 MOI	60% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3453	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.1 MOI	60% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3454	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	SRB assay	0.125 MOI	60% cell mass remain after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3455	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	CTB assay	0.075 MOI	45% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3456	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	CTB assay	0.1 MOI	45% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950
OV_3457	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of three gene beta-glucouronidase, galactosidase and GFP	No	Virus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)	No	ATCC	Human pancreatic adenocarcinoma cell line	AsPC-1	5.0E+4 cells per well	NA	CTB assay	0.125 MOI	45% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	28607950