Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 11. Click on ID to see further detail.
IDOV_2769Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultModerate cell death after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2770Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultModerate cell death after 36 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2771Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultMaximum cell death after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2772Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultModerate cell death after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2773Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultSignificant cell death after 36 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2774Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultMaximum cell death after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_4270Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineA431Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viability after day 1Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4271Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineA431Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viability after day 3Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4272Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineA431Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell viability after day 5Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_4273Virus nameMeasles virusVirus strainrMV-SLAMblindVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman nonsmall cell lung carcinoma cell lineCell lineA431Concentration of cell line5.0E+3 cells per wellIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result80% cell viability after day 7Model organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID26317644
IDOV_5922Virus nameMeasles virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationMutated for SLAM bindingVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman lung cancer cell lineCell lineA431Concentration of cell lineNAIn-vitro toxicityNAAssayWST-1 assayIn-vitro virus concentration1 MOIIn-vitro result20% cell killing after 7 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS10335481