Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3297Maraba virusMG1RNARhabdoviridaeNoneYesNoNoATCCMurine sarcoma cell lineS180NANANANANABalb/c nude mice isograft for S180 mouse tumor cell line (1.0E+6)1.0E+8 pfuNA Complete regression in tumor volume after 97 daysIntratumoralNAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_5413Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA27538520
OV_5414Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI80% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5415Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS80% confluenceNAMTT assay1 MOI50% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5416Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI90% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5417Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI90% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5418Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceMurine lymphosarcoma cell lineRLS-4080% confluenceNAMTT assay1 MOI80% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520