| Primary information |
|---|
| OV_ID | OV_3297 |
| Virus Name | Maraba virus |
| Strain | MG1 |
| Virus type | RNA |
| Virus family | Rhabdoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Murine sarcoma cell line |
| Cell line | S180 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Balb/c nude mice isograft for S180 mouse tumor cell line (1 × 10â¶) |
| In-vivo virus concentration | 1 × 10⸠pfu
|
| In-vivo toxicity | NA |
| In-vivo result | Complete regression in tumor volume after 97 days |
| Mode of delivery | Intratumoral |
| Pathway induction | NA |
| Immunogenic effect | Genration of memory immune response by incresing production of cytokines |
| Clinical trial | NA |
| PMID | 28568891 |