Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 32. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_773AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_774AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI65% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_775AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI55% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_776AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI46% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_777AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI39% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_778AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI88% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_779AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI60% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_780AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI50% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_781AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI39% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_782AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI38% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_803AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_804AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI56% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_805AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI34% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_806AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI21% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_807AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI18% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_808AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_809AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_810AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI39% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_811AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI21% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_812AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI18% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_815AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI64% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_816AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_823AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_824AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI38% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_4375Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoATCCHuman lymph node metastasis cell lineSKMEL-31000 cells per wellNALuciferase based ATP assay0.286 MOI50% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_4377Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoNCIHuman lymph node metastasis cell lineLOX-IMVI1000 cells per wellNALuciferase based ATP assay0.788 MOI50% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_4381Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoATCCHuman lymph node metastasis cell lineRPMI-7951500 cells per wellNALuciferase based ATP assay2.565 MOI50% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_4388Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoATCCHuman lymph node metastasis cell lineSKMEL-31000 cells per wellNALuciferase based ATP assay1.80 MOI80% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_4390Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoNCIHuman lymph node metastasis cell lineLOX-IMVI1000 cells per wellNALuciferase based ATP assay6 MOI80% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_4394Newcastle disease virusMTH-68/HRNAParamyxoviridaeNoneYesNoNoATCCHuman lymph node metastasis cell lineRPMI-7951500 cells per wellNALuciferase based ATP assay8.80 MOI80% cancer cell deathNoNoNA No responseNAER stress and apoptotic pathwayIFN production increasedNA26408702
OV_5636Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lymphoma cell lineRamos80% confluencyNAMTT assay1 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5637Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lymphoma cell lineDaudi80% confluencyNAMTT assay1 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426