Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 9. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1252Vesicular stomatitis viruswild typeRNARhabdoviridaeYesNoVSV in combination with cisplatin (0.1 microgram/ml)Virus expressing IL-12 geneGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOI20% cancer cell killing after 24 hoursNoNoNA No responseNANANANA18043494
OV_1253Vesicular stomatitis viruswild typeRNARhabdoviridaeYesNoVSV in combination with cisplatin (0.1 microgram/ml)Virus expressing IL-12 geneGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOI20% cancer cell killing after 48 hoursNoNoNA No responseNANANANA18043494
OV_1254Vesicular stomatitis viruswild typeRNARhabdoviridaeYesNoVSV in combination with cisplatin (0.1 microgram/ml)Virus expressing IL-12 geneGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOI20% cancer cell killing after 72 hoursNoNoNA No responseNANANANA18043494
OV_1255Vesicular stomatitis virusFusogenic strainRNARhabdoviridaeYes , expressing fusion proteinNoVSV in combination with cisplatin (0.1 microgram/ml)NoGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOINo cell killing after 24 hoursNoNoNA No responseNANANANA18043494
OV_1256Vesicular stomatitis virusFusogenic strainRNARhabdoviridaeYes , expressing fusion proteinNoVSV in combination with cisplatin (0.1 microgram/ml)NoGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOINo cell killing after 48 hoursNoNoNA No responseNANANANA18043494
OV_1257Vesicular stomatitis virusFusogenic strainRNARhabdoviridaeYes , expressing fusion proteinNoVSV in combination with cisplatin (0.1 microgram/ml)NoGibcoHuman keratinocyteHuK5.0E+4 cells per wellNAMTT assay0.01 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA18043494
OV_5557Sindbis virusAR339RNATogaviridaeNoneYesNoNoNAHuman keratinocytesEN601.0E+5 cells per wellNANA1 MOISignificant death of cancer cell line after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS7270812B2
OV_5562Reoviruswild typeRNAReoviridaeNoneYesNoNoNAHuman keratinocytesEN601.0E+5 cells per wellNANA1 MOISignificant death of cancer cell line after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS7270812B2
OV_5567Sindbis virusAR339RNATogaviridaeNoneNoSindbis virus in combination with ReovirusNoNAHuman keratinocytesEN601.0E+5 cells per wellNANA1 MOIEnhancer cytolytic effect in combination after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS7270812B2