Primary information |
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OV_ID | OV_1254 |
Virus Name | Vesicular stomatitis virus |
Strain | wild type |
Virus type | RNA |
Virus family | Rhabdoviridae |
Modification in virus genome | Yes |
Virus alone | No |
Virus in combination iwth drug/radiation | VSV in combination with cisplatin (0.1 microgram/ml) |
Immune gene induction in virus genome | Virus expressing IL-12 gene |
Source of cell line | Gibco |
Origin of cell line | Human keratinocyte |
Cell line | HuK |
Concentration of cell line | 5 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 0.01 MOI |
In-vitro result | 20% cancer cell killing after 72 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 18043494 |