Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 22. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3063Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI80% cell viabilityNoNoNA No responseNANANANA31011628
OV_3064Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻³ MOI50% cell viabilityNoNoNA No responseNANANANA31011628
OV_3065Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻² MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3093Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI85% cell viabilityNoNoNA No responseNANANANA31011628
OV_3094Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻³ MOI45% cell viabilityNoNoNA No responseNANANANA31011628
OV_3095Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻² MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3669Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3670Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI60% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3671Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3672Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI25% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3685Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3686Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI75% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3687Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3688Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI75% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3701Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI75% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3702Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman eosopahgeal cancer cell lineEC1095000 cells per wellNAMTT assay1 MOI50% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3703Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3704Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman eosopahgeal cancer cell lineKYSE 705000 cells per wellNAMTT assay1 MOI30% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_5580Sindbis virusAR339RNATogaviridaeNoneYesNoNoNAHuman eosophageal cancer cell lineYES-6NANANANANAMice xenografted for eosophageal cancer cell line YES-61.0E+6 pfuNA Complete reduction in tumor volume after 28 weeksIntratumoralInduction of apoptosis by virus infectionNANAUS7270812B2
OV_5581Sindbis virusAR339RNATogaviridaeNoneYesNoNoNAHuman eosophageal cancer cell lineYES-6NANANANANAMice xenografted for eosophageal cancer cell line YES-61.0E+6 pfuNA Complete reduction in tumor volume after 28 weeksIntraperitonealInduction of apoptosis by virus infectionNANAUS7270812B2
OV_5582Sindbis virusAR339RNATogaviridaeNoneYesNoNoNAHuman eosophageal cancer cell lineTTnNANANANANAMice xenografted for eosophageal cancer cell line TTn1.0E+6 pfuNA Tumor volume reduced to below 500mm after 32 weeksIntratumoralInduction of apoptosis by virus infectionNANAUS7270812B2
OV_5583Sindbis virusAR339RNATogaviridaeNoneYesNoNoNAHuman eosophageal cancer cell lineTTnNANANANANAMice xenografted for eosophageal cancer cell line TTn1.0E+6 pfuNA Tumor volume reduced to below 500mm after 32 weeksIntraperitonealInduction of apoptosis by virus infectionNANAUS7270812B2