Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5363Herpes simplex virusHF10DNAHerpesviridaeNoneYesNoNoNCIMurine colon carcinoma cell lineMC264000 cells per wellSlightly toxic to lymphocytesMTT assay0.001 MOI90% cell viability after 6 daysNoNoNA No responseNANAStimulation of cytotoxic CD8 T cellsNA28331843
OV_5364Herpes simplex virusHF10DNAHerpesviridaeNoneYesNoNoNCIMurine colon carcinoma cell lineMC264000 cells per wellSlightly toxic to lymphocytesMTT assay0.01 MOI60% cell viability after 6 daysNoNoNA No responseNANAStimulation of cytotoxic CD8 T cellsNA28331843
OV_5365Herpes simplex virusHF10DNAHerpesviridaeNoneYesNoNoNCIMurine colon carcinoma cell lineMC264000 cells per wellSlightly toxic to lymphocytesMTT assay0.1 MOI40% cell viability after 6 daysNoNoNA No responseNANAStimulation of cytotoxic CD8 T cellsNA28331843
OV_5366Herpes simplex virusHF10DNAHerpesviridaeNoneYesNoNoNCIMurine colon carcinoma cell lineMC264000 cells per wellSlightly toxic to lymphocytesMTT assay1 MOI5% cell viability after 6 daysNoNoNA No responseNANAStimulation of cytotoxic CD8 T cellsNA28331843
OV_5367Herpes simplex virusHF10DNAHerpesviridaeNoneYesNoNoNCIMurine colon carcinoma cell lineMC264000 cells per wellSlightly toxic to lymphocytesMTT assay10 MOI1% cell viability after 6 daysNoNoNA No responseNANAStimulation of cytotoxic CD8 T cellsNA28331843