Detailed description page of Selected OV_ID


OV_5367 details
Primary information
OV_IDOV_5367
Virus Name Herpes simplex virus
StrainHF10
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineMurine colon carcinoma cell line
Cell lineMC26
Concentration of cell line4000
In-vitro toxicitySlightly toxic to lymphocytes
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result1% cell viability after 6 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectStimulation of cytotoxic CD8 T cells
Clinical trialNA
PMID28331843