Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 23. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4216	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	10 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4217	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	0.1 MOI	7 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4218	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	6 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4219	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	GOTO	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4220	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	GOTO	1.0E+5 cells per well	NA	Luminiscence measurement	0.1 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4221	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Japanese cancer research resource bank	Human neuroblastoma cell line	GOTO	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	2 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4222	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. T. Sugimoto, Japan	Human neuroblastoma cell line	RT-BM-1	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	20 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4223	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. T. Sugimoto, Japan	Human neuroblastoma cell line	RT-BM-1	1.0E+5 cells per well	NA	Luminiscence measurement	0.1 MOI	10 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4224	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. T. Sugimoto, Japan	Human neuroblastoma cell line	RT-BM-1	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	5 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_5126	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5127	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5128	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5129	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	1 MOI	42% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5130	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5131	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5132	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	82% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5133	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.1 MOI	71% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5134	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	1 MOI	44% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5135	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5620	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroblastoma cell line	IMR-32	80% confluency	NA	MTT assay	41 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5630	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroepithelioma cell line	SK-N-MC	80% confluency	NA	MTT assay	20 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5840	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroblastoma cell line	IMR-32	80% confluency	NA	NA	41 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5850	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroepithelia cancer cell line	SK-N-MC	80% confluency	NA	NA	20 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578

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