| Primary information |
|---|
| OV_ID | OV_4220 |
| Virus Name | Sindbis virus |
| Strain | AR339 |
| Virus type | RNA |
| Virus family | Togaviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Japanese cancer research resource bank |
| Origin of cell line | Human neuroblastoma cell line |
| Cell line | GOTO |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | Luminiscence measurement |
| In-vitro virus concentration | 0.1 MOI |
| In-vitro result | 2 % cell viability after 72 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induce apoptosis process leads to cancer cell death |
| Immunogenic effect | Increased expression of Bcl-2 and Bcl-xL expression |
| Clinical trial | NA |
| PMID | 26298056 |