Please wait...
| ID | PMID | YEAR | Sequence | MAP | Name | C-ter MOD | N-ter MOD | Linear/Cyclic | Stereo-Chemistry | Modified | Length | Nature | Activity | RBCs Source | Origin | Experimental structure | Non-Hemolytic |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17307975 | 2007 | {nnr:alK}-{nnr:l}K-{nnr:l}K-{nnr:l}K | OAK 1 | Free | Free | Linear | Mix | a = amino, l = lauric acid, alK = aminolauryl-lysine | 4 | Antiplasmodial | 24.6± 1.2% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | {nnr:l}K-{nnr:l}K-{nnr:l}K-{nnr:l}K | OAK 2 | Free | Free | Linear | Mix | l = lauric acid, alK = aminolauryl-lysine | 4 | Antiplasmodial | 26.1±4.5% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | K-{nnr:l}K-{nnr:l}K-{nnr:l}K | OAK 3 | Free | Free | Linear | Mix | l = lauric acid, alK = aminolauryl-lysine | 4 | Antiplasmodial | 2.3±1.5% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | {nnr:a}{nnr:l}K-{nnr:l}K-{nnr:l}K | OAK 4 | Free | Free | Linear | Mix | a = amino, l = lauric acid | 3 | Antiplasmodial | 3.4±0.8% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | {nnr:l}K-{nnr:l}K-{nnr:l}K | OAK 5 | Free | Free | Linear | Mix | l = lauric acid, alK = aminolauryl-lysine | 3 | Antiplasmodial | 13.3±4.3% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | K-{nnr:l}K-{nnr:l}K | OAK 6 | Free | Free | Linear | Mix | l = lauric acid, alK = aminolauryl-lysine | 3 | Antiplasmodial | <0.1% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | {nnr:alK}-{nnr:l}K | OAK 7 | Free | Free | Linear | Mix | a = amino, l = lauric acid, alK = aminolauryl-lysine | 2 | Antiplasmodial | 0.14±0.3% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | {nnr:l}K-{nnr:l}K | OAK 8 | Free | Free | Linear | Mix | l = lauric acid | 2 | Antiplasmodial | 4.9±1.7% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17307975 | 2007 | K-{nnr:l}K | OAK 9 | Free | Free | Linear | Mix | l = lauric acid | 2 | Antiplasmodial | <0.1% hemolysis at 100 μM | Human | Oligoacyllysine analog (Synthetic peptide) | NA | NA | ||
| 17328560 | 2007 | FFHHIFRA{d}IVHVA{d}KTIHRLVTG | Pis-1 aa | Free | Free | Linear | Mix | None | 22 | Cytotoxic | HC50 =8μM | Human | Piscidin 1 analogs (mast cells of hybrid striped bass (Morone saxatilis x M.chrysops ) | α-helix | NA | ||
| 19132829 | 2009 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antimicrobial | HC50=21.1(±2.6)μM | Sheep | Gramicidin S (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:hpa}-PV{nnr:O}L-{nnr:hpa}-P{cyc:N-C} | GS1 | Free | Free | Cyclic | Mix | O = L-Ornithine, Hpa = homophenylalanine | 10 | Antimicrobial | HC50=7.0(±0.3)μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:1-nal}-PV{nnr:O}L-{nnr:1-nal}-P{cyc:N-C} | GS2 | Free | Free | Cyclic | Mix | O = L-Ornithine, 1-Nal = 1-naphthylalanine | 10 | Antimicrobial | HC50=5.0(±0.1)μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:2-nal}-PV{nnr:O}L-{nnr:2-nal}-P{cyc:N-C} | GS3 | Free | Free | Cyclic | Mix | O = L-Ornithine, 2-Nal = 2-naphthylalanine | 10 | Antimicrobial | HC50=7.1(±3.5)μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:dip}-PV{nnr:O}L-{nnr:dip}-P{cyc:N-C} | GS4 | Free | Free | Cyclic | Mix | O = L-Ornithine, Dip = β,β-diphenylalanine | 10 | Antimicrobial | HC50=8.6(±1.1)μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:flg}-PV{nnr:O}L-{nnr:flg}-P{cyc:N-C} | GS5 | Free | Free | Cyclic | Mix | O = L-Ornithine, Flg = fluorenylglycine | 10 | Antimicrobial | HC50=6.2(±0.3)μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19132829 | 2009 | V{nnr:O}L-{nnr:tic}-PV{nnr:O}L-{nnr:tic}-P{cyc:N-C} | GS6 | Free | Free | Cyclic | Mix | O = L-Ornithine, Tic = 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | 10 | Antimicrobial | HC50 >50 μM | Sheep | Gramicidin S analogue (Bacillus brevis) | β-sheet structure | NA | ||
| 19445503 | 2009 | RRGWVLALVL{d}RYGRR | dVAVR | Free | Free | Linear | Mix | None | 15 | Antimicrobial | 5±6 % hemolysis at 15μM | Human | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | RRGWVLALVL{d}RYGRR | dVAVR | Free | Free | Linear | Mix | None | 15 | Antimicrobial | 0 % hemolysis at 15μM | Sheep | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | RRGWVLALYL{d}RYGRR | dVAYR | Free | Free | Linear | Mix | None | 15 | Antimicrobial | 5±3% hemolysis at 15μM | Human | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | RRGWVLALYL{d}RYGRR | dVAYR | Free | Free | Linear | Mix | None | 15 | Antimicrobial | 15±20% hemolysis at 15μM | Sheep | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | RRGWALRLVL{d}AY | dARVA | Free | Free | Linear | Mix | None | 12 | Antimicrobial | 4% hemolysis at 15μM | Human | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | RRGWALRLVL{d}AY | dARVA | Free | Free | Linear | Mix | None | 12 | Antimicrobial | 10±12 % hemolysis at 15μM | Sheep | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | WVLVLRL{d}GY | dVVRG | Free | Free | Linear | Mix | None | 9 | Antimicrobial | 12±13 % hemolysis at 15μM | Human | Synthetic peptide | β-sheet | NA | ||
| 19445503 | 2009 | WVLVLRL{d}GY | dVVRG | Free | Free | Linear | Mix | None | 9 | Antimicrobial | 11±9% hemolysis at 15μM | Sheep | Synthetic peptide | β-sheet | NA | ||
| 19635451 | 2010 | GIGAV{d}LKV{d}LAL{d}ISWIK{d}RKR{ct:Amid} | Mel-dH | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | 5% hemolysis at 0.4μM | Human | Melittin analog (venom of European honey bee) | α-helix | NA | ||
| 19635451 | 2010 | GIGAV{d}LKV{d}LAL{d}ISWIK{d}RKR{ct:Amid} | Mel-dH | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | 12 % hemolysis at 23μM | Human | Melittin analog (venom of European honey bee) | α-helix | NA | ||
| 20449481 | 2010 | V{nnr:O}LLF{d}PV{nnr:O}LF{d}P{cyc:N-C} | 2HBr (1) | Free | Free | Cyclic | Mix | O = L-Ornithine | 11 | Antimicrobial | 100% hemolysis at 100μM | Sheep | Gramacidin S (Bacillus brevis ) | antiparallel β-sheet | NA | ||
| 20449481 | 2010 | V{nnr:O}LAF{d}PV{nnr:O}LF{d}P{cyc:N-C} | 2HBr (2) | Free | Free | Cyclic | Mix | O = L-Ornithine | 11 | Antimicrobial | 50% hemolysis at 100μM | Sheep | Gramacidin S (Bacillus brevis ) | antiparallel β-sheet | NA | ||
| 20449481 | 2010 | V{nnr:O}L{nnr:O}F{d}PV{nnr:O}LF{d}P{cyc:N-C} | 3HBr (3) | Free | Free | Cyclic | Mix | O = L-Ornithine | 11 | Antimicrobial | 10% hemolysis at 100μM | Sheep | Gramacidin S (Bacillus brevis ) | antiparallel β-sheet | NA | ||
| 20449481 | 2010 | V{nnr:O}LKF{d}PV{nnr:O}LF{d}P{cyc:N-C} | 3HBr (4) | Free | Free | Cyclic | Mix | O = L-Ornithine | 11 | Antimicrobial | 10% hemolysis at 100μM | Sheep | Gramacidin S (Bacillus brevis ) | antiparallel β-sheet | NA | ||
| 20449481 | 2010 | V{nnr:O}LRF{d}PV{nnr:O}LF{d}P{cyc:N-C} | 3HCl (5) | Free | Free | Cyclic | Mix | O = L-Ornithine | 11 | Antimicrobial | 15% hemolysis at 100μM | Sheep | Gramacidin S (Bacillus brevis ) | antiparallel β-sheet | NA | ||
| 20665599 | 2010 | KL{d}KK{d}LL{d}KK{d}WL{d}KL{d}LK{d}KL{d}LK{d}{ct:Amid} | D9-K9L8W | Amidation | Free | Linear | Mix | None | 18 | Antifungal | HC50 <800μM | Human | Synthetic peptide | α-helix | NA | ||
| 14709550 | 2004 | K{d}GGGK{d}WGGK{d}GGK{d}{nt:Palmitoylation}{ct:Amid} | PA-D-G | Amidation | Palmitoylation | Linear | Mix | None | 12 | Antifungal and Antibacterial | >75% hemolysis at 100µM | Human | Synthetic peptide | Random coils | NA | ||
| 14709550 | 2004 | KAA{d}A{d}KWAA{d}KA{d}AK{nt:Palmitoylation}{ct:Amid} | PA-D-A | Amidation | Palmitoylation | Linear | Mix | None | 12 | Antifungal and Antibacterial | <25% hemolysis at 100µM | Human | Synthetic peptide | Random coils | NA | ||
| 14709550 | 2004 | KVV{d}V{d}KWVV{d}KV{d}VK{nt:Palmitoylation}{ct:Amid} | PA-D-V | Amidation | Palmitoylation | Linear | Mix | None | 12 | Antifungal and Antibacterial | 100% hemolysis at 100µM | Human | Synthetic peptide | β-aggregates | NA | ||
| 14709550 | 2004 | KLL{d}L{d}KWLL{d}KL{d}LK{nt:Palmitoylation}{ct:Amid} | PA-D-L | Amidation | Palmitoylation | Linear | Mix | None | 12 | Antifungal and Antibacterial | >75% hemolysis at 100µM | Human | Synthetic peptide | α-helical | NA | ||
| 14733952 | 2004 | KWKKLLKKP{d}LKLLKKLLK{ct:Amid} | KLW-L9p | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | <5 % hemolysis at 50µM | Human | Synthetic peptide | α-helical | NA | ||
| 14733952 | 2004 | KWKKLLKKP{d}LKLLKKLLK{ct:Amid} | KLW-L9p | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | ~5% hemolysis at 100µM | Human | Synthetic peptide | α-helical | NA | ||
| 14733952 | 2004 | KWKKLLKKLLP{d}LLKKLLK{ct:Amid} | KLW-K11p | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | <20% hemolysis at 50µM | Human | Synthetic peptide | α-helical | NA | ||
| 14733952 | 2004 | KWKKLLKKLLP{d}LLKKLLK{ct:Amid} | KLW-K11p | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | >30% hemolysis at 100µM | Human | Synthetic peptide | α-helical | NA | ||
| 15009528 | 2004 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14KD4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =125 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLL{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14LD4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =5 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLF{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14FD4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =2 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLY{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14YD4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =5 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLN{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14ND4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =62 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 16730857 | 2006 | KLKF{d}KLKQ{cyc:N-C} | BPC8D | Free | Free | Cyclic | Mix | None | 8 | Hemolytic | 37±5.2% hemolysis at 360µM | Human | Synthetic peptide | NA | NA | ||
| 16730857 | 2006 | KLKLKF{d}KLKQ{cyc:N-C} | BPC10D | Free | Free | Cyclic | Mix | None | 10 | Hemolytic | 42± 6.8% hemolysis at 360µM | Human | Synthetic peptide | NA | NA | ||
| 17176094 | 2006 | RGGRLTYTRP{d}RFTVTVGR{ct:Amid} | TTpTT | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | ~10% hemolysis at above 100µg/ml | Human | Protegrins analog (porcine) | NA | NA | ||
| 17176094 | 2006 | RGGRLVYTR{nnr:p*}RFTVIVGR{ct:Amid} | TTp*TT | Amidation | Free | Linear | Mix | p* = amino-functionalized D-proline | 18 | Antimicrobial | ~20% hemolysis at above 100µg/ml | Human | Protegrins analog (porcine) | NA | NA | ||
| 17176094 | 2006 | RGGRLCYTRP{d}RFTVCVGR{ct:Amid} | CTpTC | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | ~60% hemolysis at above 100µg/ml | Human | Protegrins analog (porcine) | NA | NA | ||
| 17560323 | 2007 | HFLK{d}TLVNLAKKIL{ct:Amid} | D-Lys-4 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 110µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 17560323 | 2007 | HFLLK{d}LVNLAKKIL{ct:Amid} | D-Lys-5 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 500µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 17560323 | 2007 | HFLLTLK{d}NLAKKIL{ct:Amid} | D-Lys-7 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 500µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 17560323 | 2007 | HFLLTLVKLAKKIL{ct:Amid} | D-Lys-8 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 385µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 17560323 | 2007 | HFLLTLVNLAK{d}KIL{ct:Amid} | D-Lys-11 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 210µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 17560323 | 2007 | HFLLTLVNLAKK{d}IL{ct:Amid} | D-Lys-12 | Amidation | Free | Linear | Mix | None | 14 | Antimicrobial | LD50 = 500µM | Human | Analogs of temporin-1DRa | NA | NA | ||
| 16730857 | 2006 | KF{d}KQ{cyc:N-C} | BPC4D | Free | Free | Cyclic | Mix | None | 4 | Antibacterial | 0% hemolysis at 360µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 16730857 | 2006 | KF{d}KLKQ{cyc:N-C} | BPC6D | Free | Free | Cyclic | Mix | None | 6 | Antibacterial | 0% hemolysis at 360µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 18554256 | 2008 | GFKK{d}LLKGAAKALVKTVLF{ct:Amid} | D-Lys-4 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | LD50 = 300µM | Human | Ascaphin-8 analog (Ascaphus truei) | NA | NA | ||
| 18554256 | 2008 | GFKDLLKK{d}AAKALVKTVLF{ct:Amid} | D-Lys-8 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | LD50 = 150µM | Human | Ascaphin-8 analog (Ascaphus truei) | NA | NA | ||
| 18554256 | 2008 | GFKDLLKGAK{d}KALVKTVLF{ct:Amid} | D-Lys-10 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | LD50 >500 µM | Human | Ascaphin-8 analog (Ascaphus truei) | NA | NA | ||
| 18554256 | 2008 | GFKDLLKGAAKALVKTVLF{ct:Amid} | D-Lys-14 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | LD50 >500 µM | Human | Ascaphin-8 analog (Ascaphus truei) | NA | NA | ||
| 18554256 | 2008 | GFKDLLKGAAKALVKTVK{d}F{ct:Amid} | D-Lys-18 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | LD50 >500 µM | Human | Ascaphin-8 analog (Ascaphus truei) | NA | NA | ||
| 11478963 | 2001 | LK{d}LKSIVSWAKKVL{ct:Amid} | [D-Lys2]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 84-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11478963 | 2001 | LK{d}LKSIVSWAKKVL{ct:Amid} | [D-Lys2]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 85-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11478963 | 2001 | LKLK{d}SIVSWAKKVL{ct:Amid} | [D-Lys4]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 86-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11478963 | 2001 | LKLK{d}SIVSWAKKVL{ct:Amid} | [D-Lys4]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 87-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11478963 | 2001 | LKLKSIVSWAK{d}K{d}VL{ct:Amid} | [D-Lys11,12]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 88-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11478963 | 2001 | LKLKSIVSWAK{d}K{d}VL{ct:Amid} | [D-Lys11,12]-MP-B | Amidation | Free | Linear | Mix | None | 14 | Hypotensive | 89-85% hemolysis at 15 µM | Guinea-pig | Synthetic peptide | NA | NA | ||
| 11168889 | 2000 | PKLL{d}KTFL{d}SKWIG | Diastereo SPFK (DSac) | Free | Free | Linear | Mix | None | 13 | Antimicrobial | ~10% hemolsis at 60 µg/mL | Rat | Synthetic peptide | NA | NA | ||
| 11168889 | 2000 | PKLL{d}ETFL{d}SKWIG{ct:Amid} | Diastereo SPFK amide (DSam) | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | ~40 % hemolysis at 60 µg/mL | Rat | Synthetic peptide | NA | NA | ||
| 12110678 | 2002 | LKL{d}LKK{d}LL{d}K{d}KLLK{d}LL{ct:Amid} | Amphipathic-1D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 0% hemolysis at 100µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 12110678 | 2002 | LLK{d}KLL{d}KL{d}L{d}LKLL{d}KK{ct:Amid} | Amphipathic-2D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 0% hemolysis at 100µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 12110678 | 2002 | LLK{d}LLK{d}KL{d}L{d}KKLL{d}KL{ct:Amid} | Amphipathic-3D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 0% hemolysis at 100µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 12110678 | 2002 | KLK{d}LLK{d}LL{d}K{d}LLKL{d}LK{ct:Amid} | Scrambled-4D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 0% hemolysis at 100µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 12110678 | 2002 | KKK{d}LLL{d}LL{d}L{d}LLLK{d}KK{ct:Amid} | Scrambled-5D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 3% hemolysis at 100µM | Human | Synthetic peptide | NA | NA | ||
| 12110678 | 2002 | LLL{d}LLK{d}KK{d}K{d}KKLL{d}LL{ct:Amid} | Scrambled-6D | Amidation | Free | Linear | Mix | None | 15 | Antibacterial | 0% hemolysis at 100µM (non-hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 12712499 | 2003 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | Y{d}PY{d}P{cyc:N-C} | GS4 | Free | Free | Cyclic | Mix | None | 4 | Antibacterial and Antifungal | 100% hemolysis at >150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | KY{d}PKY{d}P{cyc:N-C} | GS6 | Free | Free | Cyclic | Mix | None | 6 | Antibacterial and Antifungal | 100% hemolysis at >150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKY{d}PKLY{d}P{cyc:N-C} | GS8 | Free | Free | Cyclic | Mix | None | 8 | Antibacterial and Antifungal | 100% hemolysis at >150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLY{d}PVKLY{d}P{cyc:N-C} | GS10 | Free | Free | Cyclic | Mix | None | 10 | Antibacterial and Antifungal | 100% hemolysis at 51–100 µg/mL | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKY{d}PKVKLY{d}P{cyc:N-C} | GS12 | Free | Free | Cyclic | Mix | None | 12 | Antibacterial and Antifungal | 100% hemolysis at >150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at <15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | V{d}KLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14V1 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/m | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VK{d}LKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K2 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/m | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKL{d}KVY{d}PLKVKLY{d}P{cyc:N-C} | GS14L3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at <15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at >150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKV{d}Y{d}PLKVKLY{d}P{cyc:N-C} | GS14V5 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 100–150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVYPLKVKLY{d}P{cyc:N-C} | GS14Y6 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/m | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}P{d}L{d}KVKLY{d}P{cyc:N-C} | GS14P7 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at <15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PL{d}KVKLY{d}P{cyc:N-C} | GS14L8 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLK{d}VKLY{d}P{cyc:N-C} | GS14K9 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 51–100 µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKV{d}KLY{d}P{cyc:N-C} | GS14V10 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at <15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKVK{d}LY{d}P{cyc:N-C} | GS14K11 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 100–150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKVKL{d}Y{d}P{cyc:N-C} | GS14L12 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKVKLYP{cyc:N-C} | GS14Y13 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at < 15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLKVY{d}PLKVKLY{d}P{d}{cyc:N-C} | GS14P14 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at < 15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 K3L4 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 100–150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | LKLK{d}LF{d}PLKLKLF{d}P{cyc:N-C} | GS14K4 Y2/F2, V3/L3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at < 15µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | LKLK{d}LY{d}PLKLKLY{d}P{cyc:N-C} | GS14K4 V3/L3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLK{d}VF{d}PLKVKLF{d}P{cyc:N-C} | GS14K4 Y2/F2 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 15-50µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at > 150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | AKLK{d}AY{d}PLKAKLY{d}P{cyc:N-C} | GS14K4 V3/A3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at > 150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | VKAK{d}VY{d}PAKVKAY{d}P{cyc:N-C} | GS14K4 L3/A3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at > 150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 12712499 | 2003 | AKAK{d}AY{d}PAKAKAY{d}P{cyc:N-C} | GS14K4 V3L3/A6 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at > 150µg/ml | Human | Gramicidin S analogs | NA | NA | ||
| 11606214 | 2001 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antimicrobial | Strong hemolysis | Human | Gramicidin S | NA | NA | ||
| 11606214 | 2001 | VKLY{d}PVKLY{d}P{cyc:N-C} | GS10 | Free | Free | Cyclic | Mix | None | 10 | Antimicrobial | Strong hemolysis | Human | Gramicidin S analogs | NA | NA | ||
| 11606214 | 2001 | VKLKY{d}PKVKLY{d}P{cyc:N-C} | GS12 | Free | Free | Cyclic | Mix | None | 12 | Antimicrobial | Weak hemolysis | Human | Gramicidin S analogs | NA | NA | ||
| 11606214 | 2001 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | Very strong hemolysis | Human | Gramicidin S analogs | NA | NA | ||
| 11606214 | 2001 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | [D-Lys]4GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | Weak hemolysis | Human | Gramicidin S analogs | NA | NA | ||
| 11682479 | 2002 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 1.5µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | LKLK{d}LF{d}PLKLKLF{d}P{cyc:N-C} | Y2/F2, V3/L3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 12.5µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | LKLK{d}LY{d}PLKLKLY{d}P{cyc:N-C} | V3/L3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 25µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | VKLK{d}VF{d}PLKVKLF{d}P{cyc:N-C} | Y2/F2 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 40µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at 200µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | AKLK{d}AY{d}PLKAKLY{d}P{cyc:N-C} | V3/A3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at >800µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | VKAK{d}VY{d}PAKVKAY{d}P{cyc:N-C} | L3/A3 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at >800µg/ml | Human | Synthetic peptide | NA | NA | ||
| 11682479 | 2002 | AKAK{d}AY{d}PAKAKAY{d}P{cyc:N-C} | V3L3/A6 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial and Antifungal | 100% hemolysis at >800µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 10µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 100µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 1% hemolysis at 10µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 8% hemolysis at 100µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K3L4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 3% hemolysis at 10µg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K3L4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 37% hemolysis at 100µg/ml | Human | Synthetic peptide | NA | NA | ||
| 12168695 | 2002 | GIGAVLKVLTTGLP{d}ALISWIKRKRQQ{ct:Amid} | Melittin-1 | Amidation | Free | Linear | Mix | None | 26 | Antibacterial | 50% hemolysis at >200µg/ml | Human | Melittin analogs | NA | NA | ||
| 12168695 | 2002 | GIGAVLKVLTTGLP{d}ALISWIKFKRQQ{ct:Amid} | Melittin-2 | Amidation | Free | Linear | Mix | None | 26 | Antibacterial | 50% hemolysis at >80µg/ml | Human | Melittin analogs | NA | NA | ||
| 12168695 | 2002 | GIGAVLKVLTTGLP{d}ALISWIKXXKRQQ{ct:Amid} | Melittin-1P | Amidation | Free | Linear | Mix | None | 27 | Antibacterial | 50% hemolysis at >18µg/ml | Human | Melittin analogs | NA | NA | ||
| 12168695 | 2002 | GIGAVLKVLTTGLP{d}ALISWIKXKRQQ{nt:Acet}{ct:Amid} | Melittin-A1P | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50% hemolysis at >200µg/ml | Human | Melittin analogs | NA | NA | ||
| 12168695 | 2002 | GIGAVLKVLTTGLP{d}ALISWIKRKRQQ{nt:Acet}{ct:Amid} | Melittin-A1 | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50% hemolysis at >200µg/ml | Human | Melittin analogs | NA | NA | ||
| 10799508 | 2000 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 10μg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 100μg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 1% hemolytic at 10μg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 8% hemolytic at 100μg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K3L4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 3% hemolytic at 10μg/ml | Human | Synthetic peptide | NA | NA | ||
| 10799508 | 2000 | VKKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K3L4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 37% hemolytic at 100μg/ml | Human | Synthetic peptide | NA | NA | ||
| 12931994 | 2003 | LRLKKRRWKYRVP{d}{cyc:N-C} | 5 | Free | Free | Cyclic | Mix | None | 13 | Antimicrobial | 1.4% hemolytic at 100μg/ml | Human | Protegrin | NA | NA | ||
| 10224074 | 1999 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antimicrobial and Hemolytic | 100% hemolytic at 12.5 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 1.5 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKV{d}KLY{d}P{cyc:N-C} | GS14V10 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 6.2 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKL{d}KVY{d}PLKVKLY{d}P{cyc:N-C} | GS14L3 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 12.5 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{d}{cyc:N-C} | GS14P14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 6.2 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}P{d}LKVKLY{d}P{cyc:N-C} | GS14P7 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 12.5 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14V1 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 40 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKL{d}Y{d}P{cyc:N-C} | GS14L12 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 25 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKV{d}Y{d}PLKVKLY{d}P{cyc:N-C} | GS14V5 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 150 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLYP{cyc:N-C} | GS14Y13 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 12.5 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PL{d}KVKLY{d}P{cyc:N-C} | GS14L8 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 50 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVYPLKVKLY{d}P{cyc:N-C} | GS14Y6 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 25 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VK{d}LKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K2 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 50 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLK{d}VKLY{d}P{cyc:N-C} | GS14K9 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 100 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 200 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVK{d}LY{d}P{cyc:N-C} | GS14K11 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at 150 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VK{d}LK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K2K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at >200 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 10224074 | 1999 | VK{d}LK{d}VY{d}PLK{d}VK{d}LY{d}P{cyc:N-C} | GS14K2K4K9K11 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial and Hemolytic | 100% hemolytic at >200 μg/ml | Human | Derivative of Gramicidin S | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSLKKTVLHTLLKAISS{nt:Acet}{ct:Amid} | P | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 5.20 ± 0.02μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLK{d}TFKSLKKTVLHTLLKAISS{nt:Acet}{ct:Amid} | K7D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 10.4 ± 0.04μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSLKK{d}TVLHTLLKAISS{nt:Acet}{ct:Amid} | K14D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 5.20 ± 0.02μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSLKKTVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 20.81 ± 0.10 μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLK{d}TFKSLKK{d}TVLHTLLKAISS{nt:Acet}{ct:Amid} | K7D/K14 D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 20.81 ± 0.15μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K14D/K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 20.81 ± 0.06μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLK{d}TFKSLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K7D/K14D/K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 81.31 ± 0.17μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC = 325.20 ± 0.82μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWK{d}SFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K3D/K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC >325.20μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | K{d}WK{d}SFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K1D/K3D/K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC >325.20μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFL{d}KTFKSLKKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L6D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =10.40 ± 0.08μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSL{d}KKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L12D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =20.81 ± 0.03μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSLKKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L20D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =20.81 ± 0.13μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFL{d}KTFKSL{d}KKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L6D/L12D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =20.81 ± 0.10 μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFLKTFKSL{d}KKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L12D/L20D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =81.31 ± 0.43μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFL{d}KTFKSL{d}KKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L6D/L12D/L20D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =162.61 ± 0.19μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFL{d}KTFKSL{d}KKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L6D/L12D/L17D/L20D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC =81.31 ± 1.05μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 22837667 | 2013 | KWKSFL{d}KTFKSL{d}KKTVLHTL{d}L{d}KAISS{nt:Acet}{ct:Amid} | L6D/L12D/L17D/L20D/L21D | Amidation | Acetylation | Linear | Mix | None | 26 | Anticancer | MHC >325.20μmol/L | Human | Synthetic α-helical cationic anticancer peptides | NA | NA | ||
| 23652359 | 2013 | KIGAK-{nnr:D-CF3-Bpg}-KIGAKIKIGAKI{ct:Amid} | KIGAKI-6D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~7% hemolysis at 7.5μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAK-{nnr:D-CF3-Bpg}-KIGAKIKIGAKI{ct:Amid} | KIGAKI-6D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~10% hemolytic at 60μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKIK-{nnr:D-CF3-Bpg}-GAKIKIGAKI{ct:Amid} | KIGAKI-8D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~5% hemolytic at 7.5μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKIK-{nnr:D-CF3-Bpg}-GAKIKIGAKI{ct:Amid} | KIGAKI-8D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~8% hemolytic at 60μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKI-12DKIGAKIKIGAK-{nnr:D-CF3-Bpg}-KIGAKI{ct:Amid} | KIGAKI-12D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~5% hemolysis at 7.5μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKI-12DKIGAKIKIGAK-{nnr:D-CF3-Bpg}-KIGAKI{ct:Amid} | KIGAKI-12D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~7% hemolysis at 60μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKIKIGAKIK-{nnr:D-CF3-Bpg}-GAKI{ct:Amid} | KIGAKI-14D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~6% hemolysis at 7.5μM | Human | KIGAKI analog | NA | NA | ||
| 23652359 | 2013 | KIGAKIKIGAKIK-{nnr:D-CF3-Bpg}-GAKI{ct:Amid} | KIGAKI-14D | Amidation | Free | Linear | Mix | CF3-Bpg = 3-(trifluoromethyl)-bicyclopent-1.1.1-1-ylglycine | 17 | Antimicrobial | ~7% hemolysis at 60μM | Human | KIGAKI analog | NA | NA | ||
| 19635451 | 2010 | GIGA{d}VLK{d}VLA{d}LISWI{d}KRKR{ct:Amid} | Mel-dH | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | 5% hemolysis at 0.4μM | Human | Melittin diastereomeric analog (Honey bee) | NA | NA | ||
| 19635451 | 2010 | GIGA{d}VLK{d}VLA{d}LISWI{d}KRKR{ct:Amid} | Mel-dH | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial | 12% hemolytic at 23μM | Human | Melittin diastereomeric analog (Honey bee) | NA | NA | ||
| 19960443 | 2010 | P{d}S{d}L{d}V{d}S{d}L{d}V{d}VQ{d}LV{d}{nnr:Δ-But}-A{d}L{d}L{d}O{d}T{d}H{d}R{d}-I-{nnr:Hse}-{nnr:dab}-K{nt:β-hydroxyoctanoyl-Δ-But} | Tolaasin | Free | β-hydroxyoctanoyl-Δ-But | Linear | Mix | Δ-But = 2,3-dehydro-2-aminobutyric acid, Hse = L-homoserine, dab = D-2,4-diaminobutyric acid | 18 | Hemolytic | 100% hemolysis at 0.53 μg/mL | Rat | Tolaasin (Pseudomonas tolaasii) | NA | NA | ||
| 20058937 | 2010 | KKL{d}L{d}KLLL{d}KL{d}LK{ct:Amid} | K5L7 | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKL{d}L{d}KLLL{d}KL{d}LK{nt:Acetylation (CH3(CH2)4CO)}{ct:Amid} | C6-K5L7 | Amidation | Acetylation (CH3(CH2)4CO) | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKL{d}L{d}KLLL{d}KL{d}LK{nt:Acetylation (CH3(CH2)6CO)}{ct:Amid} | C8-K5L7 | Amidation | Acetylation (CH3(CH2)6CO) | Linear | Mix | None | 12 | Antimicrobial | 19% hemolytic at 100μM | Human | Synthetic peptides | NA | NA | ||
| 20058937 | 2010 | KKL{d}L{d}KKLK{d}KL{d}LK{ct:Amid} | K7L5 | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKL{d}L{d}KKLK{d}KL{d}LK{nt:Acetylation (CH3(CH2)4CO)}{ct:Amid} | C6-K7L5 | Amidation | Acetylation (CH3(CH2)4CO) | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKL{d}L{d}KKLK{d}KL{d}LK{nt:Acetylation (CH3(CH2)6CO)}{ct:Amid} | C8-K7L5 | Amidation | Acetylation (CH3(CH2)6CO) | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKK{d}L{d}KKLK{d}KK{d}LK{ct:Amid} | K9L3 | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKK{d}L{d}KKLK{d}KK{d}LK{nt:Acetylation (CH3(CH2)4CO)}{ct:Amid} | C6-K9L3 | Amidation | Acetylation (CH3(CH2)4CO) | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20058937 | 2010 | KKK{d}L{d}KKLK{d}KK{d}LK{nt:Acetylation (CH3(CH2)6CO)}{ct:Amid} | C8-K9L3 | Amidation | Acetylation (CH3(CH2)6CO) | Linear | Mix | None | 12 | Antimicrobial | 0% hemolytic at 100μM (non-hemolytic) | Human | Synthetic peptides | NA | Non-hemolytic | ||
| 20848624 | 2010 | F{d}PV{nnr:O}LF{d}PV{nnr:O}L{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antimicrobial | HC50=17.5±1.07μM | Human | Gramicidin S | NA | NA | ||
| 20848624 | 2010 | F{d}PV{nnr:O}LF{d}P-{nnr:Ada}-G{nnr:O}L{cyc:N-C} | GS2 | Free | Free | Cyclic | Mix | O = L-Ornithine, Ada = Adamantylglycine | 10 | Antimicrobial | HC50=10.1±1.11μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}PV{nnr:O}LF{d}PV{nnr:O}-{nnr:Ada}-A{cyc:N-C} | GS4 | Free | Free | Cyclic | Mix | O = L-Ornithine, Ada = Adamantylglycine | 10 | Antimicrobial | HC50 =5.20±1.13μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}PV{nnr:O}-{nnr:Ada}-AF{d}PV{nnr:O}-{nnr:Ada}-A{cyc:N-C} | GS5 | Free | Free | Cyclic | Mix | O = L-Ornithine, Ada = Adamantylglycine | 10 | Antimicrobial | HC50 =10.3±1.07μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}P-{nnr:Ada}-G{nnr:O}-{nnr:Ada}-AF{d}P-{nnr:Ada}-G{nnr:O}-{nnr:Ada}-A{cyc:N-C} | GS6 | Free | Free | Cyclic | Mix | O = L-Ornithine, Ada = Adamantylglycine | 10 | Antimicrobial | HC50 =7.55±1.10μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | FP-{nnr:tBuGly}-{nnr:O}-{nnr:tBuAla}-F{d}P-{nnr:tBuGly}-{nnr:O}-{nnr:tBuAla}{cyc:N-C} | GS7 | Free | Free | Cyclic | Mix | O = L-Ornithine, tBuGly = tert-butylglycine, tBuAla = tert-butylalanine | 10 | Antimicrobial | HC50 =9.30±1.07μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}P-{nnr:Chg}-{nnr:O}-{nnr:Cha}-F{d}P-{nnr:Chg}-{nnr:O}-{nnr:Cha}{cyc:N-C} | GS8 | Free | Free | Cyclic | Mix | O = L-Ornithine, Chg = Cyclohexylglycine, Cha = Cyclohexylalanine | 10 | Antimicrobial | HC50 =9.12±1.13μM | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}P{nnr:O}V{nnr:O}{cyc:N-C} | GS9 | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antimicrobial | Non-hemolytic | Human | Gramicidin S analogue | NA | NA | ||
| 20848624 | 2010 | F{d}P{nnr:O}-{nnr:Ada}Gly-{nnr:O}F{d}P{nnr:O}-{nnr:Ada}-Gly-{nnr:O}{cyc:N-C} | GS10 | Free | Free | Cyclic | Mix | O = L-Ornithine, Ada = Adamantylglycine | 10 | Antimicrobial | HC50=107±1.07μM | Human | Gramicidin S analogue | NA | NA | ||
| 21300831 | 2011 | GKKL{d}L{d}KKL{d}KKL{d}L{d}KKG{nt:Acet}{ct:Amid} | MA-d | Amidation | Acetylation | Linear | Mix | None | 15 | Antimicrobial | 1% hemolytic at 3.4mg/ml | Human | Synthetic peptides | NA | NA | ||
| 21319749 | 2011 | FVPWFSKFLP{d}RIL{ct:Amid} | [Pro3, DPro10]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 0.6% hemolytic at 6μM | Human | Temporin L Analogues | NA | NA | ||
| 21319749 | 2011 | F{d}V{d}Q{d}W{d}F{d}S{d}K{d}F{d}L{d}GR{d}I{d}L{d}{ct:Amid} | D-TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 46% hemolytic at 6μM | Human | Temporin L Analogues | NA | NA | ||
| 21319749 | 2011 | L{d}I{d}R{d}GL{d}F{d}K{d}S{d}F{d}W{d}Q{d}V{d}F{d}{ct:Amid} | RI-TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 15% hemolytic at 6μM | Human | Temporin L Analogues | NA | NA | ||
| 21335383 | 2011 | KKLFKKILKY{d}L{ct:Amid} | BP138 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 7 ±0.1% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKILKYL{d}{ct:Amid} | BP139 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 23 ±0.9% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKILK{d}YL{ct:Amid} | BP140 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 0± 0% hemolytic at 250μM (non-hemolytic) | Human | Synthetic peptide of BP100 | NA | Non-hemolytic | ||
| 21335383 | 2011 | KKLFKKIL{d}KYL{ct:Amid} | BP141 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 4 ±0.3% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFK{d}KILKYL{ct:Amid} | BP142 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 3± 0.6% hemolysis at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLF{d}KKILKYL{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 5± 0.8% hemolysis at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKL{d}FKKILKYL{ct:Amid} | BP144 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 7±0.4% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KK{d}LFKKILKYL{ct:Amid} | BP145 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 51±0.5% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKK{d}ILKYL{ct:Amid} | BP146 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 53 ±1.1% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}KLFKKILKYL{ct:Amid} | BP147 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 71±0.4% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKI{d}LKYL{ct:Amid} | BP148 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 0±0% hemolytic at 250μM (non-hemolytic) | Human | Synthetic peptide of BP100 | NA | Non-hemolytic | ||
| 21335383 | 2011 | KKL{d}FKKILK{d}YL{ct:Amid} | BP149 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 0±0% hemolytic at 250μM (non-hemolytic) | Human | Synthetic peptide of BP100 | NA | Non-hemolytic | ||
| 21335383 | 2011 | KKLFKKIL{d}K{d}YL{ct:Amid} | BP150 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 1±0.1% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KK{d}L{d}FKK{d}ILK{d}YL{ct:Amid} | BP151 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 1±0.3% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKI{d}L{d}K{d}YL{ct:Amid} | BP152 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 5±1.6% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}LF{d}KKILKYL{ct:Amid} | BP154 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 41±6.2% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKIL{d}K{d}Y{d}L{d}{ct:Amid} | BP155 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 3±0.1% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKKL{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP156 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 49±1.2% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFKK{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP157 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 3±1.0% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLFK{d}K{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP158 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 28±2.1% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KKLF{d}K{d}K{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP159 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 58±5.7% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KK{d}L{d}F{d}K{d}K{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP160 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 65±1.9% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | KK{d}L{d}F{d}K{d}K{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP161 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 66±2.9% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}KKILKYL{ct:Amid} | BP162 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 17±0.7% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}KILKYL{ct:Amid} | BP163 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 8±5.0% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}K{d}ILKYL{ct:Amid} | BP164 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 0±0% hemolytic at 250μM (non-hemolytic) | Human | Synthetic peptide of BP100 | NA | Non-hemolytic | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}K{d}I{d}LKYL{ct:Amid} | BP165 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 6 ±0.2% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}K{d}I{d}L{d}KYL{ct:Amid} | BP166 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 1±0.2% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}K{d}I{d}L{d}K{d}YL{ct:Amid} | BP167 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 21±7.4% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21335383 | 2011 | K{d}K{d}L{d}F{d}K{d}K{d}I{d}L{d}K{d}Y{d}L{ct:Amid} | BP168 | Amidation | Free | Linear | Mix | None | 11 | Antimicrobial | 3±2.7% hemolytic at 250μM | Human | Synthetic peptide of BP100 | NA | NA | ||
| 21343499 | 2011 | EEEEAAAK{d}W{d}K{d}L{d}F{d}K{d}K{d}I{d}P{d}K{d}F{d}L{d}H{d}L{d}A{d}K{d}K{d}F{d}{nt:Acet}{ct:Amid} | Ac-E4-A3–D-P18 | Amidation | Acetylation | Linear | Mix | None | 24 | Antimcrobial and Hemolytic | ~3.5% hemolytic upto 500μM | Human | Host defense peptides analog (Rana temporaria) | NA | NA | ||
| 21729875 | 2011 | GR{d}R{d}K{d}R{d}K{d}WLR{d}R{d}IGK{d}GVK{d}IIGGAALDHL{ct:Amid} | NRC-03D | Amidation | Free | Linear | Mix | None | 26 | Anticancer | 50% hemolytic at >256 μg/ml | Human | Pleurocidin variant derived from gut and skin of pleuronectid flatfish | NA | NA | ||
| 21820306 | 2011 | {nnr:tle}-K-{nnr:tle}-A-{nnr:tle}-A-{nnr:tle}-A{cyc:N-C} | A | Free | Free | Cyclic | Mix | tle = D-Tert-leucine | 8 | Antimicrobial | HC50 =17μM | Human | Synthetic peptides | NA | NA | ||
| 21820306 | 2011 | {nnr:Tle}-K{d}-{nnr:Tle}-A{d}-{nnr:Tle}-A{d}-{nnr:Tle}-A{d}{cyc:N-C} | B | Free | Free | Cyclic | Mix | Tle = Tert-leucine | 8 | Antimicrobial | HC50 =17μM | Human | Synthetic peptides | NA | NA | ||
| 21820306 | 2011 | {nnr:tle}-K{d}-{nnr:tle}-A-{nnr:tle}-A-{nnr:tle}-A{cyc:N-C} | C | Free | Free | Cyclic | Mix | tle = D-Tert-leucine | 8 | Antimicrobial | HC50 =316μM | Human | Synthetic peptides | NA | NA | ||
| 21820306 | 2011 | {nnr:Tle}-K-{nnr:Tle}-A{d}-{nnr:Tle}-A{d}-{nnr:Tle}-A{d}{cyc:N-C} | D | Free | Free | Cyclic | Mix | Tle = Tert-leucine | 8 | Antimicrobial | HC50 =316μM | Human | Synthetic peptides | NA | NA | ||
| 20363271 | 2010 | KLKKLL{d}KKWLKL{d}LKKLLK{d}{ct:Amid} | D3-K9L8W-1 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =150μM | Human | Synthetic peptide | Random coil | NA | ||
| 20363271 | 2010 | KLKKL{d}LKKWL{d}KLLKK{d}LLK{ct:Amid} | D3-K9L8W-2 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =116μM | Human | Synthetic peptide | Random coil | NA | ||
| 20363271 | 2010 | KLKK{d}LLKK{d}WLKL{d}LKKL{d}LK{ct:Amid} | D4-K9L8W | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =800μM | Human | Synthetic peptide | Random coil | NA | ||
| 20363271 | 2010 | KL{d}K{d}KLL{d}KKW{d}LKL{d}LKK{d}LLK{d}{ct:Amid} | D6-K9L8W | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =800μM | Human | Synthetic peptide | Random coil | NA | ||
| 20363271 | 2010 | KL{d}KK{d}LL{d}KK{d}WL{d}KL{d}LK{d}KL{d}LK{d}{ct:Amid} | D9-K9L8W-1 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =800μM | Human | Synthetic peptide | Random coil | NA | ||
| 20363271 | 2010 | KLKKLLKKWL{d}K{d}L{d}L{d}K{d}K{d}L{d}L{d}K{d}{ct:Amid} | D9-K9L8W-2 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | HC50 =154μM | Human | Synthetic peptide | Random coil | NA | ||
| 20603168 | 2010 | GLKK{d}IFKAGLGSLVKGIAAHVAS | E4k | Free | Free | Linear | Mix | None | 23 | Antimicrobial | LC50 >400μM | Human | Alyteserin-1c analog | α-helical | NA | ||
| 20603168 | 2010 | GLKK{d}IFKKGLGSLVKGIAAHVAS | E4k,A8K | Free | Free | Linear | Mix | None | 23 | Antimicrobial | LC50 >400μM | Human | Alyteserin-1c analog | α-helical | NA | ||
| 20603168 | 2010 | GLKK{d}IFKAGLGSLKKGIAAHVAS | E4k,V14K | Free | Free | Linear | Mix | None | 23 | Antimicrobial | LC50 >400μM | Human | Alyteserin-1c analog | α-helical | NA | ||
| 20603168 | 2010 | GLKK{d}IFKAGLGSLVKGIKAHVAS | E4k,A18K | Free | Free | Linear | Mix | None | 23 | Antimicrobial | LC50 >400μM | Human | Alyteserin-1c analog | α-helical | NA | ||
| 21497177 | 2011 | GR{d}F{d}KRF{d}RKKF{d}KKLF{d}KKLS{ct:Amid} | BMAP -18-f | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | 10% hemolysis at >400μM | Human | BMAP-27 analog | α-helical | NA | ||
| 21682682 | 2011 | LGRVDIHVWDA{d}VYIRGR | [D-Ala66]-PNT.II | Free | Free | Linear | Mix | None | 17 | Cytotoxic | 3% hemolysis at 100μM | Human | synthetic peptide | NA | NA | ||
| 21682682 | 2011 | VDIHVWA{d}GV | D65A-PIP[59-67] | Free | Free | Linear | Mix | None | 9 | Cytotoxic | 7.5% hemolysis at 100μM | Human | synthetic peptide | NA | NA | ||
| 21682682 | 2011 | VDIHVWS{d}GV | D65S-PIP[59-67] | Free | Free | Linear | Mix | None | 9 | Cytotoxic | 1.03% hemolysis at 100μM | Human | synthetic peptide | NA | NA | ||
| 21682682 | 2011 | VDIHVWE{d}GV | D65E-PIP[59-67] | Free | Free | Linear | Mix | None | 9 | Cytotoxic | 9.9% hemolysis at 100μM | Human | synthetic peptide | NA | NA | ||
| 21682682 | 2011 | VE{d}IHVWE{d}GV | D60,65E-PIP[59-67] | Free | Free | Linear | Mix | None | 9 | Cytotoxic | 2.24% hemolysis at 100μM | Human | synthetic peptide | NA | NA | ||
| 22965637 | 2013 | ILGKLLK{d}TAAGLLSNL{ct:Amid} | S7k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =105μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLSTAAK{d}LLSNL{ct:Amid} | G11k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =42μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLSTAAGLLSK{d}L{ct:Amid} | N15k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =310μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLKTAAKLLSNL{ct:Amid} | S7K,G11K | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =38μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLK{d}TAAK{d}LLSNL{ct:Amid} | S7k,G11k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =185μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLSTAAK{d}LLSKL{ct:Amid} | G11k,N15K | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =195μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLSTAWK{d}LLSNL{ct:Amid} | A10W,G11k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =21μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22965637 | 2013 | ILGKLLSTAWALLSK{d}L{ct:Amid} | A10W,N15k | Amidation | Free | Linear | Mix | None | 16 | CPP | LC50 =27μM | Human | Alyteserin-2a analog | NA | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 18% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 8% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 5% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 7% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 4% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSK{d}FLGRIL{ct:Amid} | [Pro3, DLys7]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 2% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 94% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 19% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 19% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 17% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 5% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKF{d}LGRIL{ct:Amid} | [Pro3, DPhe8]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 4% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 9% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 8% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 7% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 3% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 2% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3, DLeu9]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 2% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 22% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 16% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 8% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 6% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 4% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGR{d}IL{ct:Amid} | [Pro3, DArg11]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 2% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 17% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 14% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 10% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 5% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 4% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFLGRI{d}L{ct:Amid} | [Pro3, DIle12]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 2% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 15% hemolysis at 48μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 17% hemolysis at 24μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 17% hemolysis at 12μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 8% hemolysis at 6μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 6% hemolysis at 3μM | Human | Temporin L analog | α-helical | NA | ||
| 22974815 | 2013 | FVPWFSKFL{d}GRIL{d}{ct:Amid} | [Pro3, DLeu13]TL | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 3% hemolysis at 1.5μM | Human | Temporin L analog | α-helical | NA | ||
| 23328867 | 2013 | THRPPMWSPVWPGGGKLL{d}LKL{d}LK{d}K{d}LLKL{d}LKKK | TfR-lytic hybrid peptide | Free | Free | Linear | Mix | None | 32 | Anticancer | 17% hemolysis at 100μM | Mouse | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | K{d}L{d}ALKLALKALKAALKLA | k1/l2 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 7μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLA{d}L{d}KLALKALKAALKLA | a3/l4 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 33μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALK{d}L{d}ALKALKAALKLA | k5/l6 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 160μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLA{d}L{d}KALKAALKLA | a7/l8 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 180μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLALK{d}A{d}LKAALKLA | k9/a10 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 56μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLALKAL{d}K{d}AALKLA | l11/k12 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 540μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLALKALKA{d}A{d}LKLA | a13/a14 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 260μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLALKALKAAL{d}K{d}LA | l15/k16 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 210μM | Human | Synthetic peptide | NA | NA | ||
| 8823199 | 1996 | KLALKLALKALKAALKL{d}A{d} | l17/a18 | Free | Free | Linear | Mix | None | 18 | Antibacterial | EC50 = 70μM | Human | Synthetic peptide | NA | NA | ||
| 9048567 | 1997 | GIGAV{d}LKV{d}LTTGLPALI{d}SWIK{d}RKRQQ{ct:Amid} | [D]-V5,8,I17,K21-melittin | Amidation | Free | Linear | Mix | None | 26 | Antibacterial | 0% hemolysis at 50μM | Human | Melittin diastereomers ( venom of the honey bee Apis mellifera) | NA | Non-hemolytic | ||
| 9048567 | 1997 | GIGAV{d}LKV{d}LTTGLPALI{d}SWIK{d}RKRQQ | [D]-V5,8,I17,K21-melittin | Free | Free | Linear | Mix | None | 26 | Antibacterial | ~1-2% hemolysis at 50μM | Human | Melittin diastereomers (Apis mellifera) | NA | NA | ||
| 8810288 | 1996 | F{d}PV{nnr:O}LF{d}PV{nnr:O}L{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = L-Ornithine | 10 | Antibacterial | 100% hemolysis at 39µg/ml | Human | Gramicidin S (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PY{d}P{cyc:N-C} | GS4 | Free | Free | Cyclic | Mix | None | 4 | Antibacterial | 100% hemolysis at >800µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PKY{d}PK{cyc:N-C} | GS6 | Free | Free | Cyclic | Mix | None | 6 | Antibacterial | 100% hemolysis at >1600µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PVKY{d}PKL{cyc:N-C} | GS8 | Free | Free | Cyclic | Mix | None | 8 | Antibacterial | 100% hemolysis at >1600µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PVKLY{d}PVKL{cyc:N-C} | GS10 | Free | Free | Cyclic | Mix | None | 10 | Antibacterial | 100% hemolysis at 67µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PVKLKY{d}PKVKL{cyc:N-C} | GS12 | Free | Free | Cyclic | Mix | None | 12 | Antibacterial | 100% hemolysis at 250µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PVKLKVY{d}PLKVKL{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antibacterial | 100% hemolysis at 6µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | Y{d}PLKVKY{d}PKLKV{cyc:N-C} | GS12LV | Free | Free | Cyclic | Mix | None | 12 | Antibacterial | 100% hemolysis at 92µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | F{d}PVKLKF{d}PKVKL{cyc:N-C} | GS12F | Free | Free | Cyclic | Mix | None | 12 | Antibacterial | 100% hemolysis at 400µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | F{d}PV{nnr:O}L{nnr:O}F{d}P{nnr:O}V{nnr:O}L{cyc:N-C} | GS12FO | Free | Free | Cyclic | Mix | O = L-Ornithine | 12 | Antibacterial | 100% hemolysis at 160µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 8810288 | 1996 | F{d}PL{nnr:O}L{nnr:O}F{d}P{nnr:O}L{nnr:O}L{cyc:N-C} | GS12FO/LL | Free | Free | Cyclic | Mix | O = L-Ornithine | 12 | Antibacterial | 100% hemolysis at 170µg/ml | Human | Gramicidin S analog (Bacillus brevis) | NA | NA | ||
| 10606532 | 1999 | KWL{d}L{d}LLKL{d}LL{d}LK{ct:Amid} | [D]L3,4,8,10-K3L8Wn | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 31% hemolysis at 50μM | Human | Synthetic peptide | NA | NA | ||
| 10606532 | 1999 | KLL{d}L{d}LWKL{d}LL{d}LK{ct:Amid} | [D]L3,4,8,10-K3L8Wm | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 39.4% hemolysis at 50μM | Human | Synthetic peptide | NA | NA | ||
| 10606532 | 1999 | KLL{d}L{d}LLKL{d}LL{d}WK{ct:Amid} | [D]L3,4,8,10-K3L8Wc | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 44.2% hemolysis at 50μM | Human | Synthetic peptide | NA | NA | ||
| 10606532 | 1999 | KWL{d}L{d}KLKL{d}KL{d}LK{ct:Amid} | [D]L3,4,8,10-K5L6Wn | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KLL{d}L{d}KWKL{d}KL{d}LK{ct:Amid} | [D]L3,4,8,10-K5L6Wm | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KLL{d}L{d}KLKL{d}KL{d}WK{ct:Amid} | [D]L3,4,8,10-K5L6Wc | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKWL{d}KLKL{d}KL{d}KK{ct:Amid} | [D]L4,8,10-K7L4Wn | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKL{d}L{d}KWKL{d}KL{d}KK{ct:Amid} | [D]L3,4,8,10-K7L4Wm | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKL{d}L{d}KLKL{d}KW{d}KK{ct:Amid} | [D]L3,4,8-K7L4Wc | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM (Non hemolytic) | Human | Synthetic peptide | NA | Non-hemolytic | ||
| 10632060 | 1999 | K{d}{Ψ[CH2NH]}KVVFKVKFKK{d}{ct:Amid} | MP1 | Amidation | Free | Linear | Mix | None | 11 | Antifungal and Antibacterial | 0% hemolysis upto 500 μg/mL (Non hemolytic) | Mouse | Synthetic peptide | NA | Non-hemolytic | ||
| 10632060 | 1999 | K{Ψ[CH2OCONH]}KVVFKVKFKK{d}{ct:Amid} | MP6 | Amidation | Free | Linear | Mix | None | 11 | Antifungal and Antibacterial | 0% hemolysis upto 500 μg/mL (Non hemolytic) | Mouse | Synthetic peptide | NA | Non-hemolytic | ||
| 9914515 | 1999 | GFFALIP{d}KIISSPLFKTL{d}L{d}SAV{ct:NH(CH2)2NH2} | [D]-P7L18,19-Par[1-22] | NH(CH2)2NH2 | Free | Linear | Mix | None | 22 | Antimicrobial | 1% hemolysis at 50μM | Human | Synthetic Peptide | NA | NA | ||
| 9914515 | 1999 | KGFFALIP{d}KIISSPLFKTL{d}L{d}SAV{ct:NH(CH2)2NH2} | K1[D]-P7L18,19-Par[1-22] | NH(CH2)2NH2 | Free | Linear | Mix | None | 23 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10224074 | 1999 | VOLF{d}PVOLF{d}P{cyc:N-C} | GS | Free | Free | Cyclic | Mix | None | 10 | Antimicrobial | 100% hemolysis at 12.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 1.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14V10 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 6.2μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKL{d}KVY{d}PLKVKLY{d}P{cyc:N-C} | GS14L3 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 12.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLY{d}P{d}{cyc:N-C} | GS14P14 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 6.2μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}P{d}LKVKLY{d}P{cyc:N-C} | GS14P7 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 12.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | V{d}KLKVYPLKVKLY{d}P{cyc:N-C} | GS14V1 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 40μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKL{d}Y{d}P{cyc:N-C} | GS14L12 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 25μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKV{d}Y{d}PLKVKLY{d}P{cyc:N-C} | GS14V5 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 150μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVKLYP{cyc:N-C} | GS14Y13 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 12.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PL{d}KVKLY{d}P{cyc:N-C} | GS14L8 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 50μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVYPLKVKLY{d}P{cyc:N-C} | GS14Y6 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 25μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VK{d}LKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14K2 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 50μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLK{d}VKLY{d}P{cyc:N-C} | GS14K9 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 100μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 200μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VKLKVY{d}PLKVK{d}LY{d}P{cyc:N-C} | GS14K11 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at 150μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VK{d}LK{d}VY{d}PLKVKLY{d}P{cyc:N-C} | GS14K2K4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at >200μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10224074 | 1999 | VK{d}LK{d}VY{d}PLK{d}VK{d}LY{d}P{cyc:N-C} | GS14K2K4K9K11 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | 100% hemolysis at >200μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 11318033 | 2001 | QL{d}LVDL{d}I{cyc:N-C} | Lichenysin | Free | Free | Cyclic | Mix | None | 7 | Chelating agent | 100% hemolysis at 15μM | Human | Bacillus licheniformis | NA | NA | ||
| 18568863 | 2008 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P | GS | Free | Free | Linear | Mix | O = L-Ornithine | 10 | Antimicrobial | MHC =12.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 18568863 | 2008 | VKLKVY{d}PLKVKLY{d}P | GS14 | Free | Free | Linear | Mix | None | 14 | Antimicrobial | MHC =1.5μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 18568863 | 2008 | VKLK{d}VY{d}PLKVKLY{d}P | GS14K4 | Free | Free | Linear | Mix | None | 14 | Antimicrobial | MHC =200μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 18568863 | 2008 | AKLK{d}AY{d}PLKAKLY{d}P | GS14K4 V3/A3 | Free | Free | Linear | Mix | None | 14 | Antimicrobial | MHC >800μg/ml | Human | Synthetic Peptide | NA | NA | ||
| 10606532 | 1999 | KWL{d}L{d}LLKL{d}LL{d}LK{ct:Amid} | [D]L3,4,8,10-K3 L8W(n) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 31% hemolysis at 50μM | Human | Synthetic Peptide | NA | NA | ||
| 10606532 | 1999 | KLL{d}L{d}LWKL{d}LL{d}LK{ct:Amid} | [D]L3,4,8,10-K3 L8W(m) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 39.4% hemolysis at 50μM | Human | Synthetic Peptide | NA | NA | ||
| 10606532 | 1999 | KLL{d}L{d}LLKL{d}LL{d}WK{ct:Amid} | [D]L3,4,8,10-K3 L8W(c) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 44.2% hemolysis at 50μM | Human | Synthetic Peptide | NA | NA | ||
| 10606532 | 1999 | KWL{d}L{d}KLKL{d}KL{d}LK{ct:Amid} | [D]L3,4,8,10-K5L6W(n) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KLL{d}L{d}KWKL{d}KL{d}LK{ct:Amid} | [D]L3,4,8,10-K5L6W(m) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KLL{d}L{d}KLKL{d}KL{d}WK{ct:Amid} | [D]L3,4,8,10-K5L6W(c) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKW{d}L{d}KLKL{d}KL{d}KK{ct:Amid} | [D]L4,8,10-K7L4W(n) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKL{d}L{d}KWKL{d}KL{d}KK{ct:Amid} | [D]L3,4,8,10-K7L4W(m) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 10606532 | 1999 | KKL{d}L{d}KLKL{d}KW{d}KK{ct:Amid} | [D]L3,4,8-K7L4W(c) | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial | 0% hemolysis at 50μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 15009528 | 2004 | VKLKVY{d}PLKVKLY{d}P{cyc:N-C} | GS14KL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =2 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14LL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =3 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLVY{d}PLKVKLY{d}P{cyc:N-C} | GS14FL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =3 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLYY{d}YPLKVKLY{d}P{cyc:N-C} | GS14YL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =8 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLNVY{d}PLKVKLY{d}P{cyc:N-C} | GS14NL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =2 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 15009528 | 2004 | VKLNVY{d}PLKVKLY{d}P{cyc:N-C} | GS14GL4 | Free | Free | Cyclic | Mix | None | 14 | Antimicrobial | MHC =3 µg/ml | Human | Gramicidin S analog | NA | NA | ||
| 23933745 | 2013 | {nnr:*}(KK({nnr:x}(CYGRKKRRQRRRCYGRKKRRQRRR))LAQLAQ){ct:Amid} | Tat-G1L | Amidation | Free | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus,x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 29 | Antimicrobial | 5 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(YGRKKRRQRRRYGRKKRRQRRRYGRKKRRQRRRYGRKKRRQRRR){nnr:x}GGGG)(KGKG)KK{d}K{nnr:*}{nt:Acet}{ct:Amid} | Tat-G2a | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus | 59 | Antimicrobial | <0.3b % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(RQIKIWFQNRRMKWKKRQIKIWFQNRRMKWKK){nnr:x}GG)KK{d}K{nnr:*}{nt:Acet}{ct:Amid} | Antp-G1a | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 39 | Antimicrobial | 1 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | {nnr:*}(KK({nnr:x}(CRQIKIWFQNRRMKWKKCRQIKIWFQNRRMKWKK))LAQLAQ){ct:Amid} | Antp-G1L | Amidation | Free | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 42 | Antimicrobial | 1 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(RQIKIWFQNRRMKWKKRQIKIWFQNRRMKWKKRQIKIWFQNRRMKWKKRQIKIWFQNRRMKWKK){nnr:x}GGGG)(KGKG)KK{d}K{nnr:*}{nt:Acet}{ct:Amid} | Antp-G2a | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 79 | Antimicrobial | <0.3b % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(LLIILRRRIRKQAHAHSKLLIILRRRIRKQAHAHSK){nnr:x}PSPS)KPSK{nnr:*}{nt:Acet}{ct:Amid} | pVEC-G1b | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 46 | Antimicrobial | <0.5b % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(AGYLLGKINKLKALAALAKKILAGYLLGKINKLKALAALAKKIL){nnr:x}PSPS)KPSK{nnr:*}{nt:Acet}{ct:Amid} | TP10K-G1b | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 54 | Antimicrobial | <0.5b % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C([VRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPP]){nnr:x}GG)KK{d}K{nnr:*}{nt:Acet}{ct:Amid} | SAP-G1a | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 43 | Antimicrobial | 41 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | {nnr:*}(KK({nnr:x}(CVRLPPPVRLPPPVRLPPPCVRLPPPVRLPPPVRLPPP))LAQLAQ){ct:Amid} | SAP-G1L | Amidation | Free | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 46 | Antimicrobial | 79 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | C([VRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPPVRLPPP]){nnr:x}GGGG)(KGKG)KkK{nnr:*}{nt:Acet}{ct:Amid} | SAP-G2a | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 87 | Antimicrobial | >173c % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | {nnr:*}(KKKK({nnr:x}(CVRLPPPVRLPPPVRLPPPCVRLPPPVRLPPPVRLPPPCVRLPPPVRLPPPVRLPPPCVRLPPPVRLPPPVRLPPP))LAQLAQLAQLAQ)4{ct:Amid} | SAP-G2L | Amidation | Free | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 92 | Antimicrobial | 41 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 23933745 | 2013 | (C(PPPLRVPPPLRVPPPLRV){nnr:x}PSC(PPPLRVPPPLRVPPPLRV){nnr:x}PSKPSK{nnr:*}{nt:Acet}{ct:Amid} | SAPr-G1b | Amidation | Acetylation | Linear | Mix | * = 5(6)-carboxyfluorescein amidated to the N-terminus, x = the S–CH2–CO– bridge between the cysteine side-chain and the N-terminus of the dendrimer or lysine side-chain | 46 | Antimicrobial | 40 % Hemolysis at 10 µM | Human | Natural Translocating Proteins | α-Helix | NA | ||
| 24185042 | 2013 | IKLSPK{d}TKDNLKKVLKGAIKGAIAVAKMV{ct:Amid} | [E6k]-1B | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 29 | Antitumor | 50 % Hemolysis at 188 ± 8 µM | Human | Congo Clawed Frog Hymenochirus Boettgeri | α-Helix | NA | ||
| 24185042 | 2013 | IKLSPETKK{d}NLKKVLKGAIKGAIAVAKMV{ct:Amid} | [D9k]-1B | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 29 | Antitumor | 50 % Hemolysis at >400 µM | Human | Congo Clawed Frog Hymenochirus Boettgeri | α-Helix | NA | ||
| 24185042 | 2013 | IKLSPK{d}TKK{d}NLKKVLKGAIKGAIAVAKMV{ct:Amid} | [E6k,D9k]-1B | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 29 | Antitumor | 50 % Hemolysis at 302 ± 21 µM | Human | Congo Clawed Frog Hymenochirus Boettgeri | α-Helix | NA | ||
| 24147906 | 2013 | A{d}L{d}L{d}L | 0 | Free | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 4 | Antibacterial | 15.6 ± 3.2 % Hemolysis at 142 µM | Human | Synthetic | α-Helical | NA | ||
| 24211081 | 2014 | IRIK{d}IR{d}IK{ct:Amid} | IK8-2D | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 8 | Antimicrobial | 10 % Hemolysis at 1600 mg/L | Rabbit | Synthetic | β-Sheet | NA | ||
| 24211081 | 2014 | II{d}R{d}KII{d}R{d}K{ct:Amid} | Control-4D | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 8 | Antimicrobial | 10 % Hemolysis at >2000 mg/L | Rabbit | Synthetic | β-Sheet | NA | ||
| 24277042 | 2014 | GLLKKI{d}KTLL{ct:Amid} | Lys5 D-Ile6 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 10 | Antimicrobial | 50 % Hemolysis at 7209 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24277042 | 2014 | GLLKKI{d}KKLL{ct:Amid} | Lys5 D-Ile6 Lys8 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 10 | Antimicrobial | 50 % Hemolysis at 1962.4 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24277042 | 2014 | G{nnr:Cha}LKR({nnr:D-2-Nal})KKLL{ct:Amid} | Cha2 D-2Nal6 Lys8 | Amidation | Free | Linear | Mix | Cha = β-cyclohexylalanine, D-2-Nal = D-3-(2-naphthyl)-L-alanine | 10 | Antimicrobial | 50 % Hemolysis at 27 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24277042 | 2014 | GLLKRiKTL{nnr:Cha}{ct:Amid} | Cha2 D-Ile6 Cha10 | Amidation | Free | Linear | Mix | Cha = β-cyclohexylalanine | 10 | Antimicrobial | 50 % Hemolysis at 225.6 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24277042 | 2014 | GLLKR({nnr:D-2-Nal})KTL{nnr:Cha}{ct:Amid} | D-2Nal6 Cha10 | Amidation | Free | Linear | Mix | Cha = β-cyclohexylalanine, D-2-Nal = D-3-(2-naphthyl)-L-alanine | 10 | Antimicrobial | 50 % Hemolysis at 74.3 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24277042 | 2014 | GLLKKI({nnr:D-2-Nal})KKL{nnr:Cha}{ct:Amid} | Lys5 D-2Nal6 Lys8 Cha10 | Amidation | Free | Linear | Mix | Cha = β-cyclohexylalanine, D-2-Nal = D-3-(2-naphthyl)-L-alanine | 10 | Antimicrobial | 50 % Hemolysis at 23.6 µM | Human | Venom Of Spider Wasp (Anoplius Samariensis) | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLK{d}TFKSLKKTVLHTLLKAISS{nt:Acet}{ct:Amid} | K7D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 10.41 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLKTFKSLKK{d}TVLHTLLKAISS{nt:Acet}{ct:Amid} | K14D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 5.2 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLKTFKSLKKTVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLK{d}TFKSLKK{d}TVLHTLLKAISS{nt:Acet}{ct:Amid} | K7D/K14D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLK{d}TFKSLKKTVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K14D/K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLK{d}TFKSLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K7D/K14D/K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 81.31 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 325.2 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWK{d}SFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K3D/K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | >325.2 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | K{d}WK{d}SFLK{d}TFK{d}SLKK{d}TVLHTLLK{d}AISS{nt:Acet}{ct:Amid} | K1D/K3D/K7D/K10D/K14D/K22D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | >325.2 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFL{d}KTFKSLKKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L6D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 10.41 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLKTFKSL{d}KKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L12D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLKTFKSLKKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L20D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFL{d}KTFKSL{d}KKTVLHTLLKAISS{nt:Acet}{ct:Amid} | L6D/L12D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 20.81 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFLKTFKSL{d}KKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L12D/L20D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 81.31 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFL{d}KTFKSL{d}KKTVLHTL{d}LKAISS{nt:Acet}{ct:Amid} | L6D/L12D/L20D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 162.61 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFL{d}KTFKSL{d}KKTVL{d}HTL{d}LKAISS{nt:Acet}{ct:Amid} | L6D/L12D /L17D/L20D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 81.3 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24805306 | 2014 | KWKSFL{d}KTFKSL{d}KKTVL{d}HTL{d}L{d}KAISS{nt:Acet}{ct:Amid} | L6D/L12D /L17D/L20 D /L21D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | >325.2 % Hemolysis at 650.4 μmol/L | Human | Peptide A12L/A20L | α-Helix | NA | ||
| 24796503 | 2014 | KLLKLLL{d}K{d}L{d}LWLKL{d}LLKLLL | Hel 13-5D3 | Free | Free | Linear | Mix | Lowercase letters correspond to D-amino acids | 18 | Pulmonary surfactant | ~100 % Hemolysis at 20 µM | Rat | Synthetic | α-Helix | NA | ||
| 24796503 | 2014 | KLLKLLL{d}K{d}L{d}LWL{d}KL{d}LLKL{d}LL | Hel 13-5D5 | Free | Free | Linear | Mix | Lowercase letters correspond to D-amino acids | 18 | Pulmonary surfactant | 35 % Hemolysis at 30-50 µM | Rat | Synthetic | α-Helix | NA | ||
| 24616110 | 2014 | GF{d}GM{d}A{d}L{d}K{d}L{d}L{d}K{d}K{d}V{d}L{d}{ct:Amid} | MAC-1/1 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 152 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | L{d}V{d}K{d}K{d}L{d}L{d}K{d}L{d}A{d}M{d}GF{d}G{ct:Amid} | MAC-1/8 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALKL{nnr:Aca}KKVL{ct:Amid} | MAC-1/24 | Amidation | Free | Linear | Mix | Aca = 1-aminocyclohexane carboxylic acid | 15 | Antimicrobial | 50 % Hemolysis at 88 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALK{nnr:Aca}LKKVL{ct:Amid} | MAC-1/25 | Amidation | Free | Linear | Mix | Aca = 1-aminocyclohexane carboxylic acid | 15 | Antimicrobial | 50 % Hemolysis at 88 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMA{nnr:Aca}KLLKKVL{ct:Amid} | MAC-1/26 | Amidation | Free | Linear | Mix | Aca = 1-aminocyclohexane carboxylic acid | 15 | Antimicrobial | 50 % Hemolysis at 93 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALKLLKKV{d}L{ct:Amid} | MAC-1/15 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >>200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALKLLKK{d}VL{ct:Amid} | MAC-1/11 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >>200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALKLLK{d}KVL{ct:Amid} | MAC-1/12 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >>200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMALK{d}LLKKVL{ct:Amid} | MAC-1/13 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >>200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGMA{d}LKLLKKVL{ct:Amid} | MAC-1/4 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFGM{d}ALKLLKKVL{ct:Amid} | MAC-1/19 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at >200 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GF{d}GMALKLLKKVL{ct:Amid} | MAC-1/6 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 177 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GFK{d}MALKLLKKVL{ct:Amid} | MAC-1/10 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 476 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | GF{d}K{d}MALKLLKKVL{ct:Amid} | MAC-1/27 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 391 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | A{d}FGMALKLLKKVL{ct:Amid} | MAC-1/28 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 120 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | A{d}FKMALKLLKKVL{ct:Amid} | MAC-1/29 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 131 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 24616110 | 2014 | A{d}FK{d}MALKLLKKVL{ct:Amid} | MAC-1/30 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 13 | Antimicrobial | 50 % Hemolysis at 476 µM | Human | Analog Of Mac-1, Venom Of Solitary Bee Macropis Fulvipes | α-Helix | NA | ||
| 25123582 | 2014 | GMASLW{d}AKVLPHVVKLIK | COD-5 | Free | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 18 | Antimicrobial | 50 % Hemolysis at >>200 µM | Human | Analog Of Cod, Venom Of Wild Bee Colletes Daviesanus | α-Helix | NA | ||
| 25241629 | 2014 | LKLSPKTKK{d}TLKKVLKGAIKGAIAIASMA{ct:Amid} | [D9k]Hymenochirin-1Pa | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 29 | Antimicrobial, Antitumor | 50 % Hemolysis at >400 µM | Human | Analog Of Hymenochirin-1Pa, Skin Secretions Ofthe Frog Pseudhymenochirus Merlini | α-Helix | NA | ||
| 25735802 | 2015 | RFRRLRW{d}KTRW{d}RLKKI{ct:Amid} | PRW4-d | Amidation | Free | Linear | Mix | w = Wd (D-Trp-substituted) | 16 | Antimicrobial, Antibacterial | 5 % Hemolysis at >256 µM | Human | Synthetic Peptide | α-Helix | Low hemolytic | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 1 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at 215 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LK{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 3 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LK{nnr:2-Nal}G{cyc:N-C} | 4 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LK{nnr:2-Nal}LK{nnr:2-Nal}G{cyc:N-C} | 5 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Abu}){cyc:N-C} | 8 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Abu = 4-aminobutyric acid | 4 | Antimicrobial | 50 % Hemolysis at 230 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:6-Ahx}{cyc:N-C} | 9 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 6-Ahx = 6-aminohexanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 115 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:8-Aoc}{cyc:N-C} | 10 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 22 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:10-Adc}{cyc:N-C} | 11 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 10-Adc = 10-aminodecanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 15 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Dab}){cyc:N-C} | 12 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid | 4 | Antimicrobial | 50 % Hemolysis at 265 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:εK}){cyc:N-C} | 13 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, εK = coupling of 2-Nal6 has occurred on lysine’s ε-amino functionality | 4 | Antimicrobial | 50 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Dab}{nnr:Dab}){cyc:N-C} | 14 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid | 4 | Antimicrobial | 50 % Hemolysis at >450 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Abu})({nnr:Dab}){cyc:N-C} | 15 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid, Abu = 4-aminobutyric acid | 4 | Antimicrobial | 50 % Hemolysis at 420 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Dab})({nnr:Abu}){cyc:N-C} | 16 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid, Abu = 4-aminobutyric acid | 4 | Antimicrobial | 50 % Hemolysis at 255 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR({nnr:Bip})LR({nnr:Bip})G{cyc:N-C} | 17 | Free | Free | Cyclic | Mix | Bip = 4,4’-biphenyl-L-alanine | 4 | Antimicrobial | 50 % Hemolysis at 16 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR({nnr:Dip})LR({nnr:Dip})G{cyc:N-C} | 18 | Free | Free | Cyclic | Mix | Dip = 3,3-diphenyl-L-alanine | 4 | Antimicrobial | 50 % Hemolysis at 145 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | {nnr:2-Aoc}R{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 19 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 55 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}G{cyc:N-C} | 20 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 33 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | ({nnr:Cha})R{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 21 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Cha = 3-cyclohexyl-L-alanine | 4 | Antimicrobial | 50 % Hemolysis at 28 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}({nnr:Cha})R{nnr:2-Nal}G{cyc:N-C} | 22 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Cha = 3-cyclohexyl-L-alanine | 4 | Antimicrobial | 50 % Hemolysis at 60 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}({nnr:Nle})R{nnr:2-Nal}G{cyc:N-C} | 23 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Nle = norleucine | 4 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | PR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 24 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 4 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}PR{nnr:2-Nal}G{cyc:N-C} | 25 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LRYG{cyc:N-C} | 26 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 6 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | TR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 27 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}TR{nnr:2-Nal}G{cyc:N-C} | 28 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | QR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 29 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:D-2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}G{cyc:N-C} | 30 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 55 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}(D-2-Aoc)R{nnr:2-Nal}G{cyc:N-C} | 31 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at 55 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR(2NalNal)LR{nnr:D-2-Nal}G{cyc:N-C} | 32 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 5 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | TR{nnr:2-Nal}IR{nnr:2-Nal}{nnr:8-Aoc}{cyc:N-C} | 33 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 4 | Antimicrobial | 50 % Hemolysis at >150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}{nnr:Dab}{nnr:Dab}{cyc:N-C} | 34 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 3 | Antimicrobial | 50 % Hemolysis at 55 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 1 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 27 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LK{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 3 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 14 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR(NalNaI)LK{nnr:2-Nal}G{cyc:N-C} | 4 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 19 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LK{nnr:2-Nal}LK{nnr:2-Nal}G{cyc:N-C} | 5 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | 13 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Abu}){cyc:N-C} | 8 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Abu = 4-aminobutyric acid | 4 | Antimicrobial | 22 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:6-Ahx}{cyc:N-C} | 9 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 6-Ahx = 6-aminohexanoic acid | 4 | Antimicrobial | 75 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:8-Aoc}{cyc:N-C} | 10 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 4 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:10-Adc}{cyc:N-C} | 11 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 10-Adc = 10-aminodecanoic acid | 4 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Dab}){cyc:N-C} | 12 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid | 4 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:εK}){cyc:N-C} | 13 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, εK = coupling of 2-Nal6 has occurred on lysine’s ε-amino functionality | 4 | Antimicrobial | 51 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}{nnr:Dab}{nnr:Dab}{cyc:N-C} | 14 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid | 4 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Abu})({nnr:Dab}){cyc:N-C} | 15 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid, Abu = 4-aminobutyric acid | 4 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:2-Nal}({nnr:Dab})({nnr:Abu}){cyc:N-C} | 16 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Dab = 2,4-diaminobutyric acid, Abu = 4-aminobutyric acid | 4 | Antimicrobial | 12 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR({nnr:Bip})LR({nnr:Bip})G{cyc:N-C} | 17 | Free | Free | Cyclic | Mix | Bip = 4,4’-biphenyl-L-alanine | 5 | Antimicrobial | 96 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR({nnr:Dip})LR({nnr:Dip})G{cyc:N-C} | 18 | Free | Free | Cyclic | Mix | Dip = 3,3-diphenyl-L-alanine | 5 | Antimicrobial | 54 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | {nnr:2-Aoc}R{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 19 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}G{cyc:N-C} | 20 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | ({nnr:Cha})R{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 21 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Cha = 3-cyclohexyl-L-alanine | 4 | Antimicrobial | 99 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}({nnr:Cha})R{nnr:2-Nal}G{cyc:N-C} | 22 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Cha = 3-cyclohexyl-L-alanine | 4 | Antimicrobial | 96 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}({nnr:Nle})R{nnr:2-Nal}G{cyc:N-C} | 23 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, Nle = norleucine | 4 | Antimicrobial | 35 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | PR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 24 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}PR{nnr:2-Nal}G{cyc:N-C} | 25 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LRYG{cyc:N-C} | 26 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 6 | Antimicrobial | 19 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | TR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 27 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}TR{nnr:2-Nal}G{cyc:N-C} | 28 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | QR{nnr:2-Nal}LR{nnr:2-Nal}G{cyc:N-C} | 29 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 5 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:D-2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}G{cyc:N-C} | 30 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 92 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}(D-2-Aoc)R{nnr:2-Nal}G{cyc:N-C} | 31 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 2-Aoc = 2-aminooctanoic acid | 4 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}LR{nnr:D-2-Nal}G{cyc:N-C} | 32 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 4 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | TR{nnr:2-Nal}IR{nnr:2-Nal}{nnr:8-Aoc}{cyc:N-C} | 33 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine, 8-Aoc = 8-aminooctanoic acid | 4 | Antimicrobial | 10 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 26318064 | 2015 | LR{nnr:2-Nal}{nnr:2-Aoc}R{nnr:2-Nal}{nnr:Dab}{nnr:Dab}{cyc:N-C} | 34 | Free | Free | Cyclic | Mix | 2-Nal = 3-(2-naphthyl)-L-alanine | 3 | Antimicrobial | 100 % Hemolysis at 150 µM | Human | Synthetic Peptide | α-Helix | NA | ||
| 25495219 | 2015 | {nnr:dab}-{nnr:Dab}-{nnr:Dab}-L-F{d}-{nnr:Dab}-{nnr:Dab}-L{ct:Amid} | 29 | Amidation | Free | Linear | Mix | Dab = diaminobutyric acid | 3 | Antimicrobial | <2 % Hemolysis at 100 µM | Mouse | Synthetic Analogues Of Battacin | NA | NA | ||
| 25495219 | 2015 | {nnr:F{d}A}-{nnr:dab}-{nnr:Dab}-{nnr:Dab}-L-F{d}-{nnr:Dab}-{nnr:Dab}-L{ct:Amid} | 17 | Amidation | Free | Linear | Mix | FA = fatty acid, Dab = diaminobutyric acid | 3 | Antimicrobial | 1.79 % Hemolysis at 100 µM | Mouse | Synthetic Analogues Of Battacin | Random coil | NA | ||
| 25495219 | 2015 | {nnr:R1}-{nnr:dab}-[{nnr:Dab}-{nnr:Dab}-L-F{d}-{nnr:Dab}-{nnr:Dab}-L] | 13 | Free | Free | Cyclic | Mix | R1 = 4-methylhexanoyl, Dab = diaminobutyric acid | 3 | Antimicrobial | 2.02 % Hemolysis at 100 µM | Mouse | Synthetic Analogues Of Battacin | NA | NA | ||
| 25495219 | 2015 | {nnr:F{d}moc}-{nnr:dab}-[{nnr:Dab}-{nnr:Dab}-L-F{d}-{nnr:Dab}-{nnr:Dab}-L] | 12 | Free | Free | Cyclic | Mix | Dab = diaminobutyric acid, Fmoc = fluorenylmethyloxycarbonyl | 3 | Antimicrobial | 41 % Hemolysis at 100 µM | Mouse | Synthetic Analogues Of Battacin | NA | NA | ||
| 25495219 | 2015 | {nnr:R3}-{nnr:dab}-{nnr:Dab}-{nnr:Dab}-L-F{d}-{nnr:Dab}-{nnr:Dab}-L{ct:Amid} | 19 | Amidation | Free | Linear | Mix | R3 = myristyl, Dab = diaminobutyric acid | 3 | Antimicrobial | 76.9 % Hemolysis at 100 µM | Mouse | Synthetic Analogues Of Battacin | NA | NA | ||
| 26574005 | 2016 | KKLF{d}KKILKYL{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Bp Analogue | NA | NA | ||
| 26574005 | 2016 | KKLFKK{d}I{d}L{d}K{d}Y{d}L{d}{ct:Amid} | BP157 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | 8 % Hemolysis at 150 µM | Human | Bp Analogue | NA | NA | ||
| 26574005 | 2016 | KKLFKKI{d}LKYL{ct:Amid} | BP207 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | Not determined | Human | Bp Analogue | NA | NA | ||
| 26574005 | 2016 | KKLF{d}KKILRYL{ct:Amid} | BP211 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | 43 % Hemolysis at 150 µM | Human | Bp Analogue | NA | NA | ||
| 26574005 | 2016 | KKL({nnr:D2-nal})KKILKYL{ct:Amid} | BP212 | Amidation | Free | Linear | Mix | D2-nal = D-2-nal | 18 | Antimicrobial | 85 % Hemolysis at 150 µM | Human | Bp Analogue | NA | NA | ||
| 26574005 | 2016 | KKLFKK{d}I{d}L{d}R{d}Y{d}L{d}{ct:Amid} | BP213 | Amidation | Free | Linear | Mix | None | 18 | Antimicrobial | <8 % Hemolysis at 150 µM | Human | Bp Analogue | NA | NA | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:iPr})({nnr:Boc}){ct:OH} | gA3K(iPr) | OH | Free | Linear | Mix | K{d} = D-lysine, fmoc = 9-fluorenylmethoxycarbonyl, iPr = Isopropyl group, Boc = ε-amino group of the lysine side chain | 15 | Antibacterial | 0 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | Non-hemolytic | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:Cy})({nnr:Boc}){ct:OH} | gA3K(Cy) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, Cy = Cyclohexyl group, Boc=ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | 55 % Hemolysis at 20 µM | Human | Bacillus Brevis | β-Helix | NA | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:CyMe})({nnr:Boc}){ct:OH} | gA3K(CyMe) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, CyMe = Cyclohexylmethyl group, Boc=ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | <90 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | NA | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:Bn})({nnr:Boc}){ct:OH} | gA3K(Bn) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, Bn = Benzyl group, Boc=ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | <90 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | NA | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:2pyr})({nnr:Boc}){ct:OH} | gA3K(2pyr) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, 2pyr = 2-Pyridyl group, Boc = ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | 0 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | Non-hemolytic | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:3pyr})({nnr:Boc}){ct:OH} | gA3K(3pyr) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, 3pyr = 3-Pyridyl group, Boc = ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | 0 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | Non-hemolytic | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:4pyr})({nnr:Boc}){ct:OH} | gA3K(4pyr) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, 4pyr = 4-Pyridyl group, Boc=ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | 0 % Hemolysis at 10 µM | Human | Bacillus Brevis | β-Helix | Non-hemolytic | ||
| 26918268 | 2016 | {nnr:Fmoc}-K{d}({nnr:4AMBn})({nnr:Boc}){ct:OH} | gA3K(4AMBn) | OH | Free | Linear | Mix | fmoc = 9-fluorenylmethoxycarbonyl, 4AMBn = 4-Aminomethylbenzyl group, Boc=ε-amino group of the lysine side chain, K{d} = D-Lys | 15 | Antibacterial | <25 % Hemolysis at 75 µM | Human | Bacillus Brevis | β-Helix | NA | ||
| 26795535 | 2016 | RGLRRLGRKIAHGVKKYGP{d}T{d}V{d}L{d}R{d}I{d}I{d}R{d}I{d}A{d}{ct:Amid} | SMAP-29-D1 | Amidation | Free | Linear | Mix | i = D-Isoleucine | 28 | Antimicrobial, Anti-MRSA, Anti-inflammatory | 10 % Hemolysis at 110 µM | Human | Smap-29 Diastereomeric Peptides | α-Helix | NA | ||
| 26795535 | 2016 | RGLRRLGRKIAHGVKKYGP{d}T{d}V{d}L{d}R{d}{nnr:i}{nnr:i}R{d}{nnr:i}A{d}{ct:Amid} | SMAP-29-D2 | Amidation | Free | Linear | Mix | i = d-allo-isoleucine | 28 | Antimicrobial, Anti-MRSA, Anti-inflammatory | 10 % Hemolysis at 217.5 µM | Human | Smap-29 Diastereomeric Peptides | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 1 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 2 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 4 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 8 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 16 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 32 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 64 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 128 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 256 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIK{d}AVGVK{d}AK{d}K{d}F{ct:Amid} | PS-PT2a | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <10 % Hemolysis at 512 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 2 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 4 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 8 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 16 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 32 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 64 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 128 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 256 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27918477 | 2016 | FLSLIPK{d}AIKAVGVKAKKF{ct:Amid} | PS-PT2b | Amidation | Free | Linear | Mix | k = D-lysine | 19 | Antimicrobial | <5 % Hemolysis at 512 mg/L | Horse | Ps-Pt Analog | α-Helix | NA | ||
| 27008420 | 2016 | KKLKK{nnr:CO-C3H7}F{d}KKLQ{cyc:N-C} | BPC712 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 30 ± 4 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKKLK-{nnr:CO-C3H7}F{d}KKLQ{cyc:N-C} | BPC726 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 12 | Anti-plant-pathogenic bacteria and fungi | 0 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC624 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 53 ± 5 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-isoC5H11}F{d}KKLQ{cyc:N-C} | BPC626 | Free | Free | Cyclic | Mix | CO-isoC5H11 = 4-methylpentanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 51 ± 7 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKKLK-{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC674 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 12 | Anti-plant-pathogenic bacteria and fungi | 51 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-C7H15}F{d}KKLQ{cyc:N-C} | BPC668 | Free | Free | Cyclic | Mix | CO-C7H15 = octanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 79 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{nnr:CO-C3H7}LKKF{d}KKLQ{cyc:N-C} | BPC714 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 3 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{nnr:CO-nC5H11}LKKF{d}KKLQ{cyc:N-C} | BPC680 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 77 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{nnr:CO-C3H7}KLKKF{d}KKLQ{cyc:N-C} | BPC716 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 2 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{nnr:CO-nC5H11}KLKKF{d}KKLQ{cyc:N-C} | BPC686 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 10 ± 0.2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-C3H7}FKKLQ{cyc:N-C} | BPC702 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 1 ± 0.1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}LK-{nnr:CO-C3H7}FKKLQ{cyc:N-C} | BPC724 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 12 | Anti-plant-pathogenic bacteria and fungi | 3 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-nC5H11}FKKLQ{cyc:N-C} | BPC628 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 19 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-isoC5H11}FKKLQ{cyc:N-C} | BPC630 | Free | Free | Cyclic | Mix | CO-isoC5H11 = 4-methylpentanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 22 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}LK-{nnr:CO-nC5H11}FKKLQ{cyc:N-C} | BPC672 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 12 | Anti-plant-pathogenic bacteria and fungi | 33 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-C7H15}FKKLQ{cyc:N-C} | BPC666 | Free | Free | Cyclic | Mix | CO-C7H15 = octanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 61 ± 2 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{d}{nnr:CO-nC5H11}LKKFKKLQ{cyc:N-C} | BPC678 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 68 ± 3 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{d}{nnr:CO-C3H7}LKKFKKLQ{cyc:N-C} | BPC704 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 9 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{d}{nnr:CO-nC5H11}KLKKFKKLQ{cyc:N-C} | BPC684 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 8 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{d}{nnr:CO-C3H7}KLKKFKKLQ{cyc:N-C} | BPC706 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 35 ± 3 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC632 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 21 ± 13 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-isoC5H11}F{d}KKLQ{cyc:N-C} | BPC634 | Free | Free | Cyclic | Mix | CO-isoC5H11 = 4-methylpentanoyl | 10 | Anti-plant-pathogenic bacteria and fungi | 7 ± 1 % Hemolysis at 150 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-C3H7}F{d}KKLQ{cyc:N-C} | BPC712 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 38 ± 7 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKKLK-{nnr:CO-C3H7}F{d}KKLQ{cyc:N-C} | BPC726 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 12 | Anti-plant-pathogenic bacteria and fungi | 4 ± 2 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC624 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 64 ± 9 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-isoC5H11}F{d}KKLQ{cyc:N-C} | BPC626 | Free | Free | Cyclic | Mix | CO-isoC5H11 = 4-methylpentanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 54 ± 4 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKKLK-{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC674 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 12 | Anti-plant-pathogenic bacteria and fungi | 56 ± 2 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{nnr:CO-C7H15}F{d}KKLQ{cyc:N-C} | BPC668 | Free | Free | Cyclic | Mix | CO-C7H15 = octanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 79 ± 1 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{nnr:CO-C3H7}LKKF{d}KKLQ{cyc:N-C} | BPC714 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 3 ± 0.5 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{nnr:CO-nC5H11}LKKF{d}KKLQ{cyc:N-C} | BPC680 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 81 ± 4 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{nnr:CO-C3H7}KLKKF{d}KKLQ{cyc:N-C} | BPC716 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 4 ± 0.5 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{nnr:CO-nC5H11}KLKKF{d}KKLQ{cyc:N-C} | BPC686 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine | 10 | Anti-plant-pathogenic bacteria and fungi | 14 ± 0.4 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-C3H7}FKKLQ{cyc:N-C} | BPC702 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 2 ± 0.3 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}LK-{nnr:CO-C3H7}FKKLQ{cyc:N-C} | BPC724 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 12 | Anti-plant-pathogenic bacteria and fungi | 3 ± 0.5 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-nC5H11}FKKLQ{cyc:N-C} | BPC628 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 34 ± 3 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-isoC5H11}FKKLQ{cyc:N-C} | BPC630 | Free | Free | Cyclic | Mix | CO-isoC5H11 = 4-methylpentanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 28 ± 3 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}LK-{nnr:CO-nC5H11}FKKLQ{cyc:N-C} | BPC672 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 12 | Anti-plant-pathogenic bacteria and fungi | 33 ± 2 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-C7H15}FKKLQ{cyc:N-C} | BPC666 | Free | Free | Cyclic | Mix | CO-C7H15 = octanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 73 ± 3 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{d}{nnr:CO-nC5H11}LKKFKKLQ{cyc:N-C} | BPC678 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 73 ± 4 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KK{d}{nnr:CO-C3H7}LKKFKKLQ{cyc:N-C} | BPC704 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 16 ± 2 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{d}{nnr:CO-nC5H11}KLKKFKKLQ{cyc:N-C} | BPC684 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 13 ± 1 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | K{d}{nnr:CO-C3H7}KLKKFKKLQ{cyc:N-C} | BPC706 | Free | Free | Cyclic | Mix | CO-C3H7 = butanoyl, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 46 ± 3 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27008420 | 2016 | KKLKK{d}{nnr:CO-nC5H11}F{d}KKLQ{cyc:N-C} | BPC632 | Free | Free | Cyclic | Mix | CO-nC5H11 = hexanoyl, f = D-phenylalanine, k = D-Lys | 10 | Anti-plant-pathogenic bacteria and fungi | 22 ± 10 % Hemolysis at 250 µM | Horse | Synthetic Cyclolipopeptides | NA | Low hemolytic | ||
| 27900727 | 2016 | IDWKKL{d}L{d}DAAKQIL{d}{ct:Amid} | D-lys-MPI | Amidation | Free | Linear | Mix | l = D-Lys lowercase letters correspond to D-amino acids | 15 | Antimicrobial | 0 % Hemolysis at 256 µM | Human | Polybia-Mpi Analogues | α-Helical | Non-hemolytic | ||
| 27992168 | 2017 | {nnr:dab}{nnr:Dab}{nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}L{nt:R1 = 4-methylhexanoyl}{ct:Amid} | GZ3.27 | Amidation | R1 = 4-methylhexanoyl | Linear | Mix | R1 = 4-methylhexanoyl, Dab = 2,4-diaminobutyric acid, dab = D-2,4-diaminobutyric acid | 3 | Antimicrobial | 1.8 ± 0.45 % Hemolysis at 100 µM | Mouse | Lipopeptide | NA | NA | ||
| 27992168 | 2017 | C{nnr:dab}{nnr:Dab}{nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}L{nt:R1 = 4-methylhexanoyl}{ct:Amid} | GZ3.163 | Amidation | R1 = 4-methylhexanoyl | Linear | Mix | R1 = 4-methylhexanoyl, Dab = 2,4-diaminobutyric acid, dab = D-2,4-diaminobutyric acid | 4 | Antimicrobial | 4.3 ± 0.42 % Hemolysis at 100 µM | Mouse | Battacin Lipopeptide Analogue | NA | NA | ||
| 27992168 | 2017 | {nnr:dab}{nnr:Dab}{nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}LC{nt:R1 = 4-methylhexanoyl}{ct:Amid} | GZ3.160 | Amidation | R1 = 4-methylhexanoyl | Linear | Mix | R1 = 4-methylhexanoyl, Dab = 2,4-diaminobutyric acid, dab = D-2,4-diaminobutyric acid | 4 | Antimicrobial | 2.8 ± 0.30 % Hemolysis at 100 µM | Mouse | Battacin Lipopeptide Analogue | NA | NA | ||
| 27992168 | 2017 | {nnr:dab}{nnr:Dab}(C){nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}L{nt:R1 = 4-methylhexanoyl}{ct:Amid} | GZ3.155 | Amidation | R1 = 4-methylhexanoyl | Linear | Mix | R1 = 4-methylhexanoyl, Dab = 2,4-diaminobutyric acid, dab = D-2,4-diaminobutyric acid | 4 | Antimicrobial | 2.2 ± 0.93 % Hemolysis at 100 µM | Mouse | Battacin Lipopeptide Analogue | NA | NA | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 8 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 15.6 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 31.2 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 62.5 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 125 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 250 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | 0 % Hemolysis at 500 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28533236 | 2017 | {nnr:Dap}L{d}WK{d}N{d}R{d}{cyc:N-C} | CLP-4 | Free | Free | Cyclic | Mix | Dap = 2,3-diaminopropionic acid, l = D-leucine, k = D-lysine, n = D-asparagine, r = D-arginine | 5 | Antibacterial, Antibiofilm | <10 % Hemolysis at 1000 μg/ml | Human | Fusaricidin | NA | Non-hemolytic | ||
| 28834399 | 2017 | YA{d}F{nnr:Cyn} | 1 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 0.8±0.1 % Hemolysis at 0 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YA{d}F{nnr:Cyn} | 1 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 2.2±0.0 % Hemolysis at 100 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YA{d}F{nnr:Cyn} | 1 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 2.4±0.1 % Hemolysis at 250 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YA{d}W{cyn} | 2 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 1.1±0.0 % Hemolysis at 0 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YA{d}W{cyn} | 2 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 1.7±0.0 % Hemolysis at 100 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YA{d}W{cyn} | 2 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, a = D-Ala | 3 | Antitumour | 2.4±0.0 % Hemolysis at 250 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}F{nnr:Cyn} | 3 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 1.2±0.1 % Hemolysis at 0 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}F{nnr:Cyn} | 3 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 1.8±0.1 % Hemolysis at 100 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}F{nnr:Cyn} | 3 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 1.8±0.1 % Hemolysis at 250 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}W{nnr:Cyn} | 4 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 0.8±0.1 % Hemolysis at 0 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}W{nnr:Cyn} | 4 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 1.0±0.1 % Hemolysis at 100 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28834399 | 2017 | YT{d}W{nnr:Cyn} | 4 | Free | Free | Linear | Mix | Cyn = trans-1-cinnamilpiperazine, t = D-Thr | 3 | Antitumour | 0.9±0.0 % Hemolysis at 250 µM | Human | Synthetic Peptidomimetics | NA | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}GRIL{ct:Amid} | 1 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 21(±4) % Hemolysis at 50 µM | Human | Amphibian Temporins | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}GRIL{ct:Amid} | 1 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 7(±3) % Hemolysis at 25 µM | Human | Amphibian Temporins | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}GRIL{ct:Amid} | 1 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 6(±3) % Hemolysis at 12.5 µM | Human | Amphibian Temporins | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}GRIL{ct:Amid} | 1 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 3(±2) % Hemolysis at 6.25 µM | Human | Amphibian Temporins | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}GRIL{ct:Amid} | 1 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 1(±1) % Hemolysis at 3.125 µM | Human | Amphibian Temporins | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | 9 | Amidation | Free | Linear | Mix | l = D-Leucine, k = D-Lys | 13 | Antibacterial | 7(±4) % Hemolysis at 50 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | 9 | Amidation | Free | Linear | Mix | l = D-Leucine, k = D-Lys | 13 | Antibacterial | 5(±3) % Hemolysis at 25 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | 9 | Amidation | Free | Linear | Mix | l = D-Leucine, k = D-Lys | 13 | Antibacterial | 5(±2) % Hemolysis at 12.5 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | 9 | Amidation | Free | Linear | Mix | l = D-Leucine, k = D-Lys | 13 | Antibacterial | 1(±2) % Hemolysis at 6.25 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | 9 | Amidation | Free | Linear | Mix | l = D-Leucine, k = D-Lys | 13 | Antibacterial | 0(±1) % Hemolysis at 3.125 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}WRIL{ct:Amid} | 10 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 37(±1) % Hemolysis at 50 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}WRIL{ct:Amid} | 10 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 20(±3) % Hemolysis at 25 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}WRIL{ct:Amid} | 10 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 7(±1) % Hemolysis at 12.5 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}WRIL{ct:Amid} | 10 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 4(±2) % Hemolysis at 6.25 µM | Human | Tl Analogue | α-Helix | NA | ||
| 28863356 | 2017 | FVPWFSKFL{d}WRIL{ct:Amid} | 10 | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial | 2(±1) % Hemolysis at 3.125 µM | Human | Tl Analogue | α-Helix | NA | ||
| 29163899 | 2017 | C{d}WK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH1 | Amidation | Free | Cyclic | Mix | None | 6 | Antimicrobial | MHC at 1000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH2 | Amidation | Free | Cyclic | Mix | None | 7 | Antimicrobial | MHC at 125 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | C{d}WW{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH3 | Amidation | Free | Cyclic | Mix | None | 8 | Antimicrobial | MHC at 500 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WW{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH4 | Amidation | Free | Cyclic | Mix | None | 9 | Antimicrobial | MHC at 125 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WW{d}KK{d}KK{d}KC{cyc:N-C}{ct:Amid} | RH5 | Amidation | Free | Cyclic | Mix | None | 10 | Antimicrobial | MHC at 1000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WW{d}WK{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH6 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 31 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | C{d}WW{d}WW{d}KK{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH7 | Amidation | Free | Cyclic | Mix | None | 12 | Antimicrobial | MHC at 31 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwWwWkKkKkC{cyc:N-C}{ct:Amid} | RH6m | Amidation | Free | Cyclic | Mix | Cyclized with α,α′-dichloro-meta-xylene | 11 | Antimicrobial | MHC at 31 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwWwWkKkKkC{cyc:N-C}{ct:Amid} | RH6o | Amidation | Free | Cyclic | Mix | Cyclized with α,α′-dichloro-ortho-xylene. | 11 | Antimicrobial | MHC at 31 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwWwWkKkKkC{cyc:N-C}{ct:Amid} | RH6ss | Amidation | Free | Cyclic | Mix | Cyclized with disulfide bridge | 11 | Antimicrobial | Minimum Hemolytic Concentration | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CF{d}FF{d}FK{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH8 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 500 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CL{d}LL{d}LK{d}KK{d}KK{d}C{cyc:N-C}{ct:Amid} | RH9 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at >2000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CK{d}KK{d}WW{d}WW{d}KK{d}C{cyc:N-C}{ct:Amid} | RH10 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 250 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WK{d}KK{d}KK{d}WW{d}C{cyc:N-C}{ct:Amid} | RH11 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 125 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | C{d}WW{d}KK{d}KK{d}KW{d}WC{d}{cyc:N-C}{ct:Amid} | dRH11 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | Minimum Hemolytic Concentration | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwWkKkKkWwC{cyc:N-C}{ct:Amid} | RH11m | Amidation | Free | Cyclic | Mix | Cyclized with α,α′-dichloro-meta-xylene | 11 | Antimicrobial | Minimum Hemolytic Concentration | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwWkKkKkWwC{cyc:N-C}{ct:Amid} | RH11o | Amidation | Free | Cyclic | Mix | Cyclized with α,α′-dichloro-ortho-xylene. | 11 | Antimicrobial | Minimum Hemolytic Concentration | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CK{d}WK{d}WK{d}WK{d}WK{d}C{cyc:N-C}{ct:Amid} | RH12 | Amidation | Free | Cyclic | Mix | None | 10 | Antimicrobial | MHC at 1000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CWW{d}KK{d}KK{d}KW{d}WW{d}C{cyc:N-C}{ct:Amid} | RH13 | Amidation | Free | Cyclic | Mix | None | 12 | Antimicrobial | MHC at 125 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | C{d}W{d}WK{d}KK{d}KK{d}WW{d}WC{d}{cyc:N-C}{ct:Amid} | dRH13 | Amidation | Free | Cyclic | Mix | None | 12 | Antimicrobial | Minimum Hemolytic Concentration | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}WK{d}KK{d}KW{d}WW{d}C{cyc:N-C}{ct:Amid} | RH14 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 8 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CW{d}KK{d}KK{d}KK{d}WW{d}C{cyc:N-C}{ct:Amid} | RH15 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 250 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CL{d}LK{d}KK{d}KK{d}LL{d}C{cyc:N-C}{ct:Amid} | RH16 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at >2000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CWWKKKKKWWC{cyc:N-C}{ct:Amid} | RH17 | Amidation | Free | Cyclic | Mix | None | 11 | Antimicrobial | MHC at 250 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | C({nnr:Me})wWkKkKkW({nnr:Me})wC{cyc:N-C}{ct:Amid} | RH18 | Amidation | Free | Cyclic | Mix | Me = N-methylation of the peptide bond. | 11 | Antimicrobial | MHC at 8 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | Cw({nnr:Me})WkKkKkW({nnr:Me})wC{cyc:N-C}{ct:Amid} | RH19 | Amidation | Free | Cyclic | Mix | Me = N-methylation of the peptide bond. | 11 | Antimicrobial | MHC at 1000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 29163899 | 2017 | CwW({nnr:Me})kKkK({nnr:Me})kWwC{cyc:N-C}{ct:Amid} | RH20 | Amidation | Free | Cyclic | Mix | Me = N-methylation of the peptide bond. | 11 | Antimicrobial | MHC at 1000 µg/mL | Human | Camp | β-Sheet | NA | ||
| 28833783 | 2017 | IDWKKLLKAAK{nnr:Pra}IL{cyc:N-C}{nt:Acet}{ct:Amid} | C-MPI-1 | Amidation | Acetylation | Cyclic | Mix | Pra = L-propargylglycine | 16 | Antimicrobial | 30 % Hemolysis at 50 µM | Human | Mpi Analogs | α-Helical | NA | ||
| 28833783 | 2017 | IDWKKLLKAAK{nnr:Pra}IL{cyc:N-C}{nt:Acet}{ct:Amid} | C-MPI-1 | Amidation | Acetylation | Cyclic | Mix | Pra = L-propargylglycine | 16 | Antimicrobial | 35 % Hemolysis at 150 µM | Human | Mpi Analogs | α-Helical | NA | ||
| 28981608 | 2017 | ILGTILGLLK{d}SL{ct:Amid} | D-lys-CP | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 12 | Antimicrobial | 0 % Hemolysis at <20 µM | Human | D-Lysine Substituted Derivative | α-Helical | Non-hemolytic | ||
| 28981608 | 2017 | ILGTILGLLK{d}SL{ct:Amid} | D-lys-CP | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 12 | Antimicrobial | 0 % Hemolysis at >30 µM | Human | D-Lysine Substituted Derivative | α-Helical | Non-hemolytic | ||
| 28981608 | 2017 | ILGTILGLLK{d}SL{ct:Amid} | D-lys-CP | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 12 | Antimicrobial | 0 % Hemolysis at <70 µM | Human | D-Lysine Substituted Derivative | α-Helical | Non-hemolytic | ||
| 28981608 | 2017 | ILGTILGLLK{d}SL{ct:Amid} | D-lys-CP | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 12 | Antimicrobial | 0.2 % Hemolysis at 130 µM | Human | D-Lysine Substituted Derivative | α-Helical | NA | ||
| 38062792 | 2023 | K{d}K{d}LLK{d}LLK{d}LLL | ln69 | Free | Free | Linear | Mix | k = D-lysine | 11 | Antimicrobial | MHC at 1000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | {nnr:Nlys}KLLKLLK{d}LL{nnr:Nleu} | EB2 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at >2000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | KKLLK{nnr:Nleu}{nnr:Nleu}{nnr:Nlys}{nnr:Nleu}{nnr:Nleu}{nnr:Nleu} | EB4 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at >2000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | {nnr:Nlys}{nnr:Nlys}{nnr:Nleu}{nnr:Nleu}{nnr:Nlys}LLKLLL | EB5 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at 1000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | {nnr:Nlys}{nnr:Nlys}LL{nnr:Nlys}LLKLLL | EB6 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at 250 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | {nnr:Nlys}{nnr:Nlys}LL{nnr:Nlys}LL{nnr:Nlys}LLL | EB7 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at >2000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | K{nnr:Nlys}L{nnr:Nleu}K{nnr:Nleu}L{nnr:Nlys}L{nnr:Nleu}L | EB9 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at >2000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 38062792 | 2023 | {nnr:Nlys}K{nnr:Nleu}L{nnr:Nlys}L{nnr:Nleu}K{nnr:Nleu}L{nnr:Nleu} | EB10 | Free | Free | Linear | Mix | NLys = (lysine-like residue), NLeu = (leucine-like residue) | 11 | Antimicrobial | MHC at >2000 μg/mL | Human | Peptide−Peptoid Hybrids | α-Helical | NA | ||
| 37797458 | 2023 | VDKPPYLPRPRPPRR{d}IYNR{d}{ct:Amid} | Oncocin112(8) | Amidation | Free | Linear | Mix | None | 21 | Antimicrobial | 3.3 % Hemolysis at 800 μg/mL | Human | Analogues Of Oncocin | NA | NA | ||
| 37797458 | 2023 | VDK({nnr:Hyp})({nnr:Hyp})YLPRPR({nnr:Hyp})PRR{d}IYNR{d}{ct:Amid} | 9 | Amidation | Free | Linear | Mix | Hyp = trans-4-Hydroxy-l-proline | 17 | Antimicrobial | 1.2 % Hemolysis at 800 μg/mL | Human | Analogues Of Oncocin | NA | NA | ||
| 37797458 | 2023 | VDK({nnr:Dfp})({nnr:Dfp})YLPRPR({nnr:Dfp})PRR{d}IYNR{d}{ct:Amid} | 10 | Amidation | Free | Linear | Mix | Dfp = 4,4-Difluoro-l-proline | 17 | Antimicrobial | 0.2 % Hemolysis at 800 μg/mL | Human | Analogues Of Oncocin | NA | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 0.19 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 0.39 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 0.78 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 1.56 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 3.12 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 6.25 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 12.5 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 25 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 50 µM | Human | Synthetic | α-Helical | NA | ||
| 38657271 | 2024 | P{d}KSRLHKWAND{nnr:Aic}EDRTYQ{nt:Acet}{ct:Amid} | SR16 | Amidation | Acetylation | Linear | Mix | p = D-Proline, Aic = α-aminoisobutyric acid | 18 | Antiviral | <5 % Hemolysis at 100 µM | Human | Synthetic | α-Helical | NA | ||
| 29077406 | 2017 | F{d}PV{nnr:O}L-F{d}PV{nnr:O}L{cyc:N-C} | GS | Free | Free | Cyclic | Mix | O = Ornithine, f = D-Phenylalanine | 10 | Antimicrobial | 90 % Hemolysis at 12 μg/mL | Human | Aneurinibacillus Migulanus | C2-symmetric antiparallel β-Sheet | NA | ||
| 29077406 | 2017 | F{d}({nnr:Dyp})V{nnr:O}LF{d}PV{nnr:O}L{cyc:N-C} | GS mimetic 15 | Free | Free | Cyclic | Mix | O = Ornithine, Dyp = cis-dihydroxyproline, f = D-Phenylalanine | 10 | Antimicrobial | 90 % Hemolysis at 85 μg/mL | Human | Gs Derivative Synthesized | β-Turn | NA | ||
| 29077406 | 2017 | {nnr:D-Hot═Tap}-V-{nnr:O}-L-F{d}-P-V-{nnr:O}-L{cyc:N-C} | dimethylketal modified GS analogue | Free | Free | Cyclic | Mix | O = Ornithine, Dyp = cis-dihydroxyproline, D-Hot═Tap = D-Hot═Tap, f = D-Phenylalanine | 9 | Antimicrobial | 90 % Hemolysis at >200 μg/mL | Human | Dihydroxylated Dipeptide D-Hot═Tap (D-Hydroxythreonine═Thiaproline With The “═” Representing The Two Covalent Ring Connections) | twisted β-Sheet structure | NA | ||
| 29077406 | 2017 | {nnr:D-Hot[(7S,8S)-{nnr:O}-(2(S)-decyliden)]═Tap}-V-{nnr:O}-L-F{d}-P-V-{nnr:O}-L{cyc:N-C} | GS mimetic 17 | Free | Free | Cyclic | Mix | O = Ornithine, Dyp = cis-dihydroxyproline, D-Hot═Tap = D-Hot═Tap, f = D-Phenylalanine | 10 | Antimicrobial | 90 % Hemolysis at 38 μg/mL | Human | Gs Analogue Modified With A C8- Alkyl Chain | twisted β-Sheet structure | NA | ||
| 29077406 | 2017 | {nnr:D-Hot[(7S,8S)-{nnr:O}-(2(S)-pentadecyliden)]═Tap}-V-{nnr:O}-L- F{d}-P-V-{nnr:O}-L{cyc:N-C} | GS mimetic 18 | Free | Free | Cyclic | Mix | O = Ornithine, Dyp = cis-dihydroxyproline, D-Hot═Tap = D-Hot═Tap, f = D-Phenylalanine | 10 | Antimicrobial | 90 % Hemolysis at 6 μg/mL | Human | Gs Analogue 18 Modified With A C13-Alkyl Chain | twisted β-Sheet structure | NA | ||
| 29077406 | 2017 | {nnr:D-Hot[(7S,8S)-{nnr:O}-(2(S)-8-pentadecyliden)]═Tap}-V-{nnr:O}L-F{d}-P-V-{nnr:O}-L{cyc:N-C} | GS mimetic 19 | Free | Free | Cyclic | Mix | O = Ornithine, Dyp = cis-dihydroxyproline, D-Hot═Tap = D-Hot═Tap, f = D-Phenylalanine | 10 | Antimicrobial | 90 % Hemolysis at 5 μg/mL | Human | Gs Analogue Modified With Two C7-Alkyl Chains | twisted β-Sheet structure | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R1}{ct:Amid} | C6-Pat | Amidation | R1 = hexanoyl | Linear | Mix | R1 = hexanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.61 ± 0.25 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}V{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2}{ct:Amid} | C7Val2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.95 ± 0.45 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2}{ct:Amid} | C7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 1.77 ± 0.81 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2}{ct:Amid} | C7Phe2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 1.28 ± 1.65 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2}{ct:Amid} | C7DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 26.5 ± 4.45 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2}{ct:Amid} | C7Phe2DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 8.34 ± 1.80 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R2}{ct:Amid} | C7Phe2DLeu7Phe8-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 64.2 ± 3.28 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R3}{ct:Amid} | C8-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 25.3 ± 4.15 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3}{ct:Amid} | Dab9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 2.25 ± 2.18 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}{nnr:Dab}{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3}{ct:Amid} | Dab2,9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.80 ± 0.40 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:O}I{nnr:O}F{d}L{nnr:O}V{d}LS{nt:R3}{ct:Amid} | Orn-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Orn = Ornithine | 9 | ND = not detected | 1.12 ± 0.47 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R4}{ct:Amid} | C10-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 93.9 ± 7.57 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}ITL{d}L{nnr:Dab}V{d}LS{nt:R4}{ct:Amid} | C10Thr3Leu4-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 24.9 ± 2.71 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R5}{ct:Amid} | Benzoyl-Pat | Amidation | R5 = benzoyl | Linear | Mix | R5 = benzoyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.70 ± 0.34 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R6}{ct:Amid} | Cbz-Pat | Amidation | R6 = benzyloxycarbonyl | Linear | Mix | R6 = benzyloxycarbonyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.65 ± 0.29 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R7}{ct:Amid} | Cha-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 1.63 ± 0.40 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R7}{ct:Amid} | ChaPhe2DLeu7Phe8-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 34.6 ± 0.91 % Hemolysis at 128 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R1 = hexanoyl}{ct:{nt:R4}{ct:Amid}} | C6-Pat | Amidation | R1 = hexanoyl | Linear | Mix | R1 = hexanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.08 ± 0.85 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}V{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Val2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.79 ± 0.63 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 1.18 ± 0.68 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.60 ± 1.35 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 4.86 ± 1.05 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 2.03 ± 0.44 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7Phe8-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 18.8 ± 2.44 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R3 = octanoyl}{ct:Amid} | C8-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 6.18 ± 2.48 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.73 ± 0.50 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}{nnr:Dab}{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab2,9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.41 ± 0.53 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:O}I{nnr:O}F{d}L{nnr:O}V{d}LS{nt:R3}{ct:Amid}{nt:R3 = octanoyl}{ct:Amid} | Orn-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Orn = Ornithine | 9 | ND = not detected | 0.69 ± 0.64 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 73.4 ± 7.59 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}ITL{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10Thr3Leu4-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 10.0 ± 1.03 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R5 = benzoyl}{ct:Amid} | Benzoyl-Pat | Amidation | R5 = benzoyl | Linear | Mix | R5 = benzoyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 1.14 ± 1.05 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R6 = benzyloxycarbonyl}{ct:Amid} | Cbz-Pat | Amidation | R6 = benzyloxycarbonyl | Linear | Mix | R6 = benzyloxycarbonyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.54 ± 0.70 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | Cha-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.65 ± 0.62 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | ChaPhe2DLeu7Phe8-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 11.02 ± 0.99 % Hemolysis at 64 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R1 = hexanoyl}{ct:Amid} | C6-Pat | Amidation | R1 = hexanoyl | Linear | Mix | R1 = hexanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.41 ± 0.58 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}V{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Val2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.32 ± 0.74 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.78 ± 0.30 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.49 ± 1.22 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 1.39 ± 0.55 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.39 ± 0.30 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7Phe8-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 5.10 ± 1.26 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R3 = octanoyl}{ct:Amid} | C8-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 1.91 ± 0.25 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.80 ± 0.68 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}{nnr:Dab}{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab2,9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.38 ± 0.62 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:O}I{nnr:O}F{d}L{nnr:O}V{d}LS{nt:R3}{ct:Amid}{nt:R3 = octanoyl}{ct:Amid} | Orn-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Orn = Ornithine | 9 | ND = not detected | 0.44 ± 0.30 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | broad Antibacterial activity | 37.2 ± 8.62 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}ITL{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10Thr3Leu4-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 5.06 ± 1.14 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R5 = benzoyl}{ct:Amid} | Benzoyl-Pat | Amidation | R5 = benzoyl | Linear | Mix | R5 = benzoyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.71 ± 0.82 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R6 = benzyloxycarbonyl}{ct:Amid} | Cbz-Pat | Amidation | R6 = benzyloxycarbonyl | Linear | Mix | R6 = benzyloxycarbonyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.41 ± 0.67 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | Cha-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.33 ± 0.83 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | ChaPhe2DLeu7Phe8-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 2.46 ± 0.34 % Hemolysis at 32 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R1 = hexanoyl}{ct:Amid} | C6-Pat | Amidation | R1 = hexanoyl | Linear | Mix | R1 = hexanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.48 ± 0.64 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}V{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Val2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | −0.17 ± 0.19 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.18 ± 0.54 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.28 ± 1.11 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.96 ± 0.59 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}LS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.14 ± 0.20 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R2 = heptanoyl}{ct:Amid} | C7Phe2DLeu7Phe8-Pat | Amidation | R2 = heptanoyl | Linear | Mix | R2 = heptanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.99 ± 0.31 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R3 = octanoyl}{ct:Amid} | C8-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 0.93 ± 0.45 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.52 ± 0.58 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}{nnr:Dab}{nnr:Dab}F{d}L{nnr:Dab}V{d}L{nnr:Dab}{nt:R3 = octanoyl}{ct:Amid} | Dab2,9-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 0.37 ± 0.62 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:O}I{nnr:O}F{d}L{nnr:O}V{d}LS{nt:R3}{ct:Amid}{nt:R3 = octanoyl}{ct:Amid} | Orn-Pat | Amidation | R3 = octanoyl | Linear | Mix | R3 = octanoyl, Orn = Ornithine | 9 | ND = not detected | 0.86 ± 0.72 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | Antibacterial | 14.3 ± 4.25 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}ITL{d}L{nnr:Dab}V{d}LS{nt:R4 = decanoyl}{ct:Amid} | C10Thr3Leu4-Pat | Amidation | R4 = decanoyl | Linear | Mix | R4 = decanoyl, Dab = 2,4-diaminobutyric acid | 9 | ND = not detected | 1.25 ± 0.71 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | NA | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R5 = benzoyl}{ct:Amid} | Benzoyl-Pat | Amidation | R5 = benzoyl | Linear | Mix | R5 = benzoyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.22 ± 0.17 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R6 = benzyloxycarbonyl}{ct:Amid} | Cbz-Pat | Amidation | R6 = benzyloxycarbonyl | Linear | Mix | R6 = benzyloxycarbonyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.77 ± 0.15 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}I{nnr:Dab}F{d}L{nnr:Dab}V{d}LS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | Cha-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.55 ± 0.75 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29136469 | 2017 | {nnr:Dab}F{nnr:Dab}F{d}L{nnr:Dab}L{d}FS{nt:R7 = 3-cyclohexylalanyl}{ct:Amid} | ChaPhe2DLeu7Phe8-Pat | Amidation | R7 = 3-cyclohexylalanyl | Linear | Mix | R7 = 3-cyclohexylalanyl, Dab = 2,4-diaminobutyric acid | 9 | Antimicrobial | 0.60 ± 0.18 % Hemolysis at 16 μg/ml | Rabbit | Synthetic Paenipeptins Analogues | NA | Low hemolytic | ||
| 29140694 | 2017 | F{d}PFF{d}NQYV{nnr:O}L{cyc:N-C} | Tyrocidine A | Free | Free | Cyclic | Mix | BE2 = 2-AMINOBENZOIC ACID, f = D-Phenylalanine, O = L-Ornithine | 10 | Antimicrobial | 100 % Hemolysis at 5 μg/ml | Mouse | Bacillus Brevis | β-Hairpin | NA | ||
| 29140694 | 2017 | F{d}{nnr:BE2}FF{d}NQYV{nnr:O}L{cyc:N-C} | Tyrocidine A analogue AC3.27 | Free | Free | Cyclic | Mix | BE2 = 2-AMINOBENZOIC ACID, f = D-Phenylalanine, O = L-Ornithine | 10 | Antifungal | ~60 % Hemolysis at 38 μg/ml | Mouse | Synthetic Analogue Of Tyrocidine A | β-Hairpin | NA | ||
| 29140694 | 2017 | F{d}{nnr:BE2}FF{d}NKYV{nnr:O}L{cyc:N-C} | Tyrocidine A analogue AC3.28 | Free | Free | Cyclic | Mix | BE2 = 2-AMINOBENZOIC ACID, f = D-Phenylalanine, O = L-Ornithine | 10 | Antifungal | ~60 % Hemolysis at 38 μg/ml | Mouse | Synthetic Analogue Of Tyrocidine A | β-Hairpin | NA | ||
| 29188836 | 2017 | F{d}PVRLF{d}PVRL{cyc:N-C} | GS-2 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 10.03±0.49 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | A{d}PVRLF{d}PVRL{cyc:N-C} | MGR-1 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 67.18±2.94 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}AVRLF{d}PVRL{cyc:N-C} | MGR-2 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 55.03±1.77 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PARLF{d}PVRL{cyc:N-C} | MGR-3 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 30.56±1.80 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PVALF{d}PVRL{cyc:N-C} | MGR-4 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 14.41±0.51 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PVRAF{d}PVRL{cyc:N-C} | MGR-5 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 36.33±1.98 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | A{d}PVRLA{d}PVRL{cyc:N-C} | DGR-1 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 137.40±6.20 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}AVRLF{d}AVRL{cyc:N-C} | DGR-2 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 199.90±9.80 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PARLF{d}PARL{cyc:N-C} | DGR-3 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at 88.95±7.51 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PVALF{d}PVAL{cyc:N-C} | DGR-4 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at >200 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29188836 | 2017 | F{d}PVRAF{d}PVRA{cyc:N-C} | DGR-5 | Free | Free | Cyclic | Mix | None | 10 | Antibiotic | 50 % Hemolysis at >200 (mean±SD, μM) | Human | Bacillus Brevis (Gramicidin S (Gs)) | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKSAKK{d}TVLHTALKAISS{nt:Acet}{ct:Amid} | K14D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 125 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKS{d}AKK{d}TVLHTALKAISS{nt:Acet}{ct:Amid} | S11D/K14D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 125 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKSAKK{d}T{d}VLHTALKAISS{nt:Acet}{ct:Amid} | K14D/T15D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 250 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKS{d}AKK{d}T{d}VLHTALKAISS{nt:Acet}{ct:Amid} | S11D/K14D/T15D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 250 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKSA{d}KKTVLHTALKAISS{nt:Acet}{ct:Amid} | A12D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 125 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKSA{d}KKTVLHTALKAISS{nt:Acet}{ct:Amid} | F9D/A12D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | <20 % Hemolysis at 250 μM | Human | V13K Analogs | NA | Low hemolytic | ||
| 29280948 | 2017 | KWKSFLKTFKSA{d}KKTVLHTALKAISS{nt:Acet}{ct:Amid} | A12D/V16D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 0 % Hemolysis at >500 μM | Human | V13K Analogs | NA | Non-hemolytic | ||
| 29280948 | 2017 | KWKSFLKTF{d}KSA{d}KKTV{d}LHTALKAISS{nt:Acet}{ct:Amid} | F9D/A12D/V16D | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acids | 26 | Antimicrobial | 0 % Hemolysis at >500 μM | Human | V13K Analogs | NA | Non-hemolytic | ||
| 29310083 | 2018 | K{d}W{d}LK{d}K{d}W{d}LK{d}W{d}LK{d}K{d}{ct:Amid} | DA-12 | Amidation | Free | Linear | Mix | None | 12 | Antibacterial | 0 % Hemolysis at 250 μg/ml | Human | Analogues Of Α/Β Diastereomeric Peptide | α-Helical | Non-hemolytic | ||
| 29310083 | 2018 | K{d}W{d}{nnr:L}K{d}K{d}W{d}{nnr:L}K{d}W{d}{nnr:L}K{d}K{d}{ct:Amid} | UNA-12 | Amidation | Free | Linear | Mix | L = β-amino acid | 12 | Antibacterial | 0 % Hemolysis at 250 μg/ml | Human | Analogues Of Α/Β Diastereomeric Peptide | α-Helical | Non-hemolytic | ||
| 29407961 | 2018 | {nnr:dab}{nnr:Dab}{nnr:Dab}L{nnr:dab}{nnr:Dab}{nnr:Dab}L{nnr:dab}{nnr:Dab}{nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}L{nnr:dab}{nnr:Dab}{nnr:Dab}LF{d}{nnr:Dab}{nnr:Dab}L{nt:R6 = 4-methyl-hexanoyl}{ct:Amid} | Lipopeptide-13 | Amidation | R6 = 4-methyl-hexanoyl | Linear | Mix | Dab = 2,4-diaminobutanoic acid, dab = D-2,4-diaminobutanoic acid, f = D-phenylalanine | 24 | Antifungal, Antibiofilm | 21 % Hemolysis at 1 mM | Mouse | Linear Battacin Analogue | NA | NA | ||
| 29501941 | 2018 | VGAL{d}AV{d}VV{d}WL{d}WL{d}WL{d}W{nt:Formyl}{ct:NHCH2CH2OH}{nt:Formyl}{ct:NHCH2CH2OH} | 24(Gramicidin A) | NHCH2CH2OH | Formyl | Linear | Mix | N-Terminal = Formyl | 15 | Antibacterial | 50 % Hemolysis at 5 µM | Human | Gramicidin A Amp | β 6.3-Helical | NA | ||
| 29738954 | 2018 | FG{nnr:r}KKR{nnr:r}Q{nnr:r}R{nnr:r}-{nnr:βA}{nt:Acet}{ct:Amid} | γTatM4 | Amidation | Acetylation | Linear | Mix | r = (2S,4S)-4-amino-N-(3-guanidinopropyl)-proline, βA = βAla(β-Alanine){nnr:Bala} – β-Alanine | 11 | Antibacterial and Anti-TB | 10 % Hemolysis at 1 µM | Human | Tat Peptide Analogues | NA | NA | ||
| 29738954 | 2018 | FG{nnr:r}KKR{nnr:r}Q{nnr:r}R{nnr:r}-{nnr:βA}{nt:Acet}{ct:Amid} | γTatM4 | Amidation | Acetylation | Linear | Mix | r = (2S,4S)-4-amino-N-(3-guanidinopropyl)-proline, βA = βAla(β-Alanine){nnr:Bala} – β-Alanine | 11 | Antibacterial and Anti-TB | 12 % Hemolysis at 40 µM | Human | Tat Peptide Analogues | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{cyc:N-C} | C1 | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Npm = N-(1-phenylmethyl)glycine | 6 | Antibacterial | 10 % Hemolysis at 250 μg/mL | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Ndmb}{nnr:Nap}{nnr:Ndmb}{nnr:Nap}{nnr:Ndmb}{cyc:N-C} | C2 | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Ndmb = N-(3,5-dimethylbenzyl)glycine | 6 | Antibacterial | 10 % Hemolysis at 125 μg/mL | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Nsne}{nnr:Nap}{nnr:Nsne}{nnr:Nap}{nnr:Nsne}{cyc:N-C} | C3 | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Nsne = (S)-N-(1-naphthylethyl)glycine | 6 | Antibacterial | 10 % Hemolysis | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Ndp}{nnr:Nap}{nnr:Ndp}{nnr:Nap}{nnr:Ndp}{cyc:N-C} | C4 | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Ndp = N-(2,2-diphenylethyl)glycine | 6 | Antibacterial | 10 % Hemolysis at 31.3 μg/mL | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Nbtfmb}{nnr:Nap}{nnr:Nbtfmb}{nnr:Nap}{nnr:Nbtfmb}{cyc:N-C} | C5 | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Nbtfmb = N-(3,5-bis-trifluoromethylbenzyl)glycine | 6 | Antibacterial | 10 % Hemolysis at 31.3 μg/mL | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | {nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{nnr:Nap}{nnr:Npm}{cyc:N-C} | C1dec | Free | Free | Cyclic | Mix | Nap = N-(3-aminopropyl)glycine, Npm = N-(1-phenylmethyl)glycine | 10 | Antibacterial | 10 % Hemolysis at 250 μg/mL | Human | Synthetic Peptoids Mimic Antimicrobial Peptides | NA | NA | ||
| 29621496 | 2018 | V{nnr:O}LF{d}PV{nnr:O}LF{d}P{cyc:N-C} | CGS (gramicidin S) | Free | Free | Cyclic | Mix | O = L-Ornithine, f = D-phenylalanine | 10 | Antibacterial | 10 % Hemolysis at >15.6 μg/mL | Human | Gram-Positive Bacterium Brevibacillus Brevis | NA | NA | ||
| 29799150 | 2018 | AAGK{d}W{d}K{d}L{d}F{d}K{d}K{d}L{d}P{d}K{d}F{d}L{d}H{d}L{d}A{d}K{d}K{d}F{d}{ct:Amid} | AAG‐P18 | Amidation | Free | Linear | Mix | None | 18 | Antibacterial | 75 % Hemolysis at 250 μM | Human | Cecropin/Magainin Hybrid | NA | NA | ||
| 29799150 | 2018 | EEEEAAAGK{d}W{d}K{d}L{d}F{d}K{d}K{d}L{d}P{d}K{d}F{d}L{d}H{d}L{d}A{d}K{d}K{d}F{d}{nt:Acet}{ct:Amid} | Pro‐P18 | Amidation | Acetylation | Linear | Mix | None | 26 | ND | 0 % Hemolysis at 10 μM | Human | Cecropin/Magainin Hybrid | NA | Non-hemolytic | ||
| 29799150 | 2018 | AAGW{d}G{d}L{d}R{d}R{d}L{d}L{d}K{d}Y{d}G{d}K{d}R{d}S{d}{ct:Amid} | AAG‐WMR | Amidation | Free | Linear | Mix | None | 13 | Antibacterial | 5 % Hemolysis at 10 μM | Human | Myxinidin Analogue From Hagfish | NA | NA | ||
| 29799150 | 2018 | EEEEAAAGW{d}G{d}L{d}R{d}R{d}L{d}L{d}K{d}Y{d}G{d}K{d}R{d}S{d}{nt:Acet}{ct:Amid} | Pro‐WMR | Amidation | Acetylation | Linear | Mix | None | 21 | ND | 0 % Hemolysis at 10 μM | Human | Myxinidin Analogue From Hagfish | NA | Non-hemolytic | ||
| 29750913 | 2018 | C{d}ILC-KKLFKKILKYL{cyc:1‑4} | Cyclo (1‑4)‑cILC-BP100 | Free | Free | Cyclic | Mix | disulfide bond between D-Cys1 and Cys4 at N-Terminal | 11 | Antimicrobial | 50 % Hemolysis at 8.7 μM | Human | Synthesized Analog Of Bp100 | membrane =Partly α-Helical and partly β-Turn | NA | ||
| 29900628 | 2018 | RVRWRlF{d}-{nnr:2-Abz}-A{d}RWRVR | Peptide 2 | Free | Free | Linear | Mix | 2-Abz = 2-aminobenzoic acid, f = D-Phenylalanine | 13 | Antibacterial, Antifungal | <3 % Hemolysis at 200 μM | Mouse | Synthetic Amphipathic Antimicrobial Peptide | aqueous = β‐Hairpin | Low hemolytic | ||
| 29900628 | 2018 | RIKWRlF{d}-{nnr:2-Abz}-A{d}RWKIR | Peptide 3 | Free | Free | Linear | Mix | 2-Abz = 2-aminobenzoic acid, f = D-Phenylalanine | 13 | Antibacterial | <3 % Hemolysis at 600 μM | Mouse | Synthetic Amphipathic Antimicrobial Peptide | aqueous = β‐Hairpin | Non-hemolytic | ||
| 30105347 | 2018 | ADLPFE{d}F | PapR7-dE | Free | Free | Linear | Mix | e = D-glutamic acid | 7 | NA | 50 % Hemolysis at 1 μM | Human | Synthetic Peptide | NA | NA | ||
| 29760411 | 2018 | L/I-A-L/I-L/I-L/I-R-L/I -L/I-V-K-L/I-(K-K-S-L/I-T-L/I-K-V-L/I-L/I-R-I/L){cyc:N-C} | Paenialvin-A | Free | Free | Bicyclic | Mix | None | 23 | Antibacterial,Antitumor | 3.61 % Hemolysis at 50 μg/ml | Rabbit | Bacteria Paenibacillus Alvei Dsm 29 | NA | Non-hemolytic | ||
| 29760411 | 2018 | L/I-A-L/I-L/I-I/L-R-L/I -L/I-V-K-L/I-(K-K-A-L/I-T-L/I-K-V-L/I-L/I-R-I/L){cyc:N-C} | Paenialvin-B | Free | Free | Bicyclic | Mix | None | 23 | Antibacterial | 1.93 % Hemolysis at 50 μg/ml | Rabbit | Bacteria Paenibacillus Alvei Dsm 29 | NA | Non-hemolytic | ||
| 29760411 | 2018 | FVPAILCSILKTC | Paenialvin-D | Free | Free | Linear | Mix | None | 16 | Antibacterial | 0.64 % Hemolysis at 50 μg/ml | Rabbit | Bacteria Paenibacillus Alvei Dsm 29 | NA | Non-hemolytic | ||
| 30192822 | 2018 | KLLKFVTKVGKAIFKALIKAI{d} | Ocellatin4-analogue | Free | Free | Linear | Mix | None | 21 | Antimicrobial | 88 % Hemolysis at 25 mM | Human | Leptodatylus Ocellatus Analogue Of Ocellatin 4 | amphipathic α-Helix | NA | ||
| 30192822 | 2018 | KLLKFVTKVGKAIFKALIKAI{d} | Ocellatin4-analogue | Free | Free | Linear | Mix | None | 21 | Antimicrobial | 100 % Hemolysis at 50 mM | Human | Leptodatylus Ocellatus Analogue Of Ocellatin 4 | amphipathic α-Helix | NA | ||
| 30192822 | 2018 | KLLKFVTKVGKAIFKALIKAI{d} | Ocellatin4-analogue | Free | Free | Linear | Mix | None | 21 | Antimicrobial | 100 % Hemolysis at 75 mM | Human | Leptodatylus Ocellatus Analogue Of Ocellatin 4 | amphipathic α-Helix | NA | ||
| 30192822 | 2018 | KLLKFVTKVGKAIFKALIKAI{d} | Ocellatin4-analogue | Free | Free | Linear | Mix | None | 21 | Antimicrobial | 100 % Hemolysis at 100 mM | Human | Leptodatylus Ocellatus Analogue Of Ocellatin 4 | amphipathic α-Helix | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:cf}KK{cyc:N-C} | 5a | Free | Free | Cyclic | Mix | β = lipophilic β2,2‐amino acid, cf = 4-CF3 (β-phenylalanine derivative has a trifluoromethyl CF3 ) | 4 | Antibacterial | 50 % Hemolysis at >500 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:cf}GK{cyc:N-C} | 5b | Free | Free | Cyclic | Mix | β = lipophilic β2,2‐amino acid, cf = 4-CF3 (β-phenylalanine derivative has a trifluoromethyl CF3 ) | 4 | Antibacterial | 50 % Hemolysis at >500 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:cf}AK{cyc:N-C} | 5c | Free | Free | Cyclic | Mix | β = lipophilic β2,2‐amino acid, cf = 4-CF3 (β-phenylalanine derivative has a trifluoromethyl CF3 ) | 4 | Antibacterial | 50 % Hemolysis at >500 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:cf}FK{cyc:N-C} | 5d | Free | Free | Cyclic | Mix | β = lipophilic β2,2‐amino acid, cf = 4-CF3 (β-phenylalanine derivative has a trifluoromethyl CF3 ) | 4 | Antibacterial | 50 % Hemolysis at 88 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:dicf}KK{cyc:N-C} | 6a | Free | Free | Cyclic | Mix | β = β^(2,2), dicf = 3,5diCF3(β-phenylalanine derivative has trifluoromethyl CF3 groups) | 4 | Antibacterial | 50 % Hemolysis at 216 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:dicf}GK{cyc:N-C} | 6b | Free | Free | Cyclic | Mix | β = β^(2,2), dicf = 3,5diCF3(β-phenylalanine derivative has trifluoromethyl CF3 groups) | 4 | Antibacterial | 50 % Hemolysis at 100 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:dicf}AK{cyc:N-C} | 6c | Free | Free | Cyclic | Mix | β = β^(2,2), dicf = 3,5diCF3(β-phenylalanine derivative has trifluoromethyl CF3 groups) | 4 | Antibacterial | 50 % Hemolysis at 67 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30112781 | 2018 | K{nnr:β}{nnr:dicf}FK{cyc:N-C} | 6d | Free | Free | Cyclic | Mix | β = β^(2,2), dicf = 3,5diCF3(β-phenylalanine derivative has trifluoromethyl CF3 groups) | 4 | Antibacterial | 50 % Hemolysis at 84 μg/mL | Human | Synthetic Cyclic Amps | NA | NA | ||
| 30135470 | 2018 | {nnr:R}-{nnr:dab}V{nnr:dab}FL{nnr:dab}VLS{cyc:N-C} | PGP-E | Free | Free | Cyclic | Mix | Dab = Diaminobutyric acid, R = CH2CH2CH3(propyl group) | 9 | Antimicrobial | <50 % Hemolysis at 200 µM | Human | Bacteria Paenibacillus Elgii Bc34-6 | NA | NA | ||
| 30325566 | 2018 | ELL{d}VDL{d}L{cyc:N-C}{nt:Amid} | surfactin | Free | Amidation | Cyclic | Mix | l = D-Leucine | 7 | Antimicrobial | high % Hemolysis at 100 µM | Human | Bacteria Bacillus Subtilis | NA | NA | ||
| 30361948 | 2018 | K{nnr:*}WK{nnr:Nle}{nnr:*}K{ct:Amid} | KKK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 3 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WK{nnr:Nle}{nnr:*}K{ct:Amid} | RKK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 4.3 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | K{nnr:*}WR{nnr:Nle}{nnr:*}K{ct:Amid} | KRK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 2 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | K{nnr:*}WK{nnr:Nle}{nnr:*}R{ct:Amid} | KKR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 5.4 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | R{nnr:*}WR{nnr:Nle}{nnr:*}K{ct:Amid} | RRK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | <1 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Non-hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WK{nnr:Nle}{nnr:*}R{ct:Amid} | RKR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 17 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | K{nnr:*}WR{nnr:Nle}{nnr:*}R{ct:Amid} | KRR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 5.6 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | R{nnr:*}WR{nnr:Nle}{nnr:*}R{ct:Amid} | RRR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 3.2 % Hemolysis at 50 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | K{nnr:*}WK{nnr:Nle}{nnr:*}K{ct:Amid} | KKK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 1.5 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WK{nnr:Nle}{nnr:*}K{ct:Amid} | RKK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 1.5 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | K{nnr:*}WR{nnr:Nle}{nnr:*}K{ct:Amid} | KRK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | < 1 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Non-hemolytic | ||
| 30361948 | 2018 | K{nnr:*}WK{nnr:Nle}{nnr:*}R{ct:Amid} | KKR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 1.4 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WR{nnr:Nle}{nnr:*}K{ct:Amid} | RRK | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | < 1 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Non-hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WK{nnr:Nle}{nnr:*}R{ct:Amid} | RKR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 8.2 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | NA | ||
| 30361948 | 2018 | K{nnr:*}WR{nnr:Nle}{nnr:*}R{ct:Amid} | KRR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | 1.8 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Low hemolytic | ||
| 30361948 | 2018 | R{nnr:*}WR{nnr:Nle}{nnr:*}R{ct:Amid} | RRR | Amidation | Free | Linear | Mix | Nle = Norleucine, oct4-enyl = hydrocarbon staple, * = shows the staple site | 7 | Antibacterial | < 1 % Hemolysis at 25 µM | Human | Synthetic Stapled Heptapeptides | ɑ-Helix | Non-hemolytic | ||
| 34377965 | 2019 | K{d}L{d}LS{d}L{d}L{d}LT{d}L{d}S{d}LA{d}K{d}A{d}A{d}K{d}L{d}LT{d}L{d}L{d}LA{d}L{d}S{d}L{nt:Acet}{ct:Amid} | D84 (Lys1-6 Lys-1) | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50 % Hemolysis at 54.3 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}{nnr:Dab}A{d}K{d}A{d}A{d}K{d}L{d}{nnr:Dab}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}{nnr:Dab}{nt:Acet}{ct:Amid} | D86 (Lys1-6 Dab-1) | Amidation | Acetylation | Linear | Mix | L-Dab = (2,4-diaminobutyric acid) | 26 | Antibacterial | 50 % Hemolysis at >742 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}{nnr:Dap}S{d}L{d}L{d}{nnr:Dap}T{d}L{d}S{d}{nnr:Dap}A{d}K{d}A{d}A{d}K{d}L{d}{nnr:Dap}T{d}L{d}L{d}{nnr:Dap}A{d}L{d}S{d}{nnr:Dap}{nt:Acet}{ct:Amid} | D105 (Lys1-6 Dap-1) | Amidation | Acetylation | Linear | Mix | L-Dap = (2,3-diaminopropionic acid) | 26 | Antibacterial | 50 % Hemolysis at >1148 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}LS{d}L{d}L{d}LT{d}L{d}S{d}LA{d}K{d}A{d}A{d}K{d}L{d}LT{d}L{d}L{d}LA{d}L{d}S{d}S{nt:Acet}{ct:Amid} | D101 (Lys1Ser26-5 Lys-1) | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50 % Hemolysis at 103.9 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}{nnr:Dab}A{d}K{d}A{d}A{d}K{d}L{d}{nnr:Dab}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}S{nt:Acet}{ct:Amid} | D102 (Lys1Ser26-5 Dab-1) | Amidation | Acetylation | Linear | Mix | L-Dab = (2,4-diaminobutyric acid) | 26 | Antibacterial | 50 % Hemolysis at >708 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}LS{d}L{d}L{d}LT{d}L{d}S{d}A{d}A{d}K{d}LLK{d}L{d}A{d}T{d}L{d}L{d}LA{d}L{d}S{d}L{nt:Acet}{ct:Amid} | D88 (Lys1-6 Lys-2) | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50 % Hemolysis at 80.6 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | AKR{nnr:bip}{nnr:bip}GYKRKF{nnr:bip}{nt:Acet}{ct:Amid} | D89 (Lys1-6 Dab-2) | Amidation | Acetylation | Linear | Mix | L-Dab = (2,4-diaminobutyric acid) | 26 | Antibacterial | 50 % Hemolysis at >1112 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}{nnr:Dap}S{d}L{d}L{d}{nnr:Dap}T{d}L{d}S{d}A{d}A{d}K{d}{nnr:Dap}{nnr:Dap}K{d}L{d}A{d}T{d}L{d}L{d}{nnr:Dap}A{d}L{d}S{d}{nnr:Dap}{nt:Acet}{ct:Amid} | D106 (Lys1-6 Dap-2) | Amidation | Acetylation | Linear | Mix | L-Dap = (2,3-diaminopropionic acid) | 26 | Antibacterial | 50 % Hemolysis at 340.2 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}LS{d}L{d}L{d}LT{d}L{d}S{d}A{d}A{d}K{d}LLK{d}L{d}A{d}T{d}L{d}L{d}LA{d}L{d}S{d}S{nt:Acet}{ct:Amid} | D103 (Lys1Ser26-5 Lys-2) | Amidation | Acetylation | Linear | Mix | None | 26 | Antibacterial | 50 % Hemolysis at 134.9 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 34377965 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}A{d}A{d}K{d}{nnr:Dab}{nnr:Dab}K{d}L{d}A{d}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}S{nt:Acet}{ct:Amid} | D104 (Lys1Ser26-5 Dab-2) | Amidation | Acetylation | Linear | Mix | L-Dab = (2,4-diaminobutyric acid) | 26 | Antibacterial | 50 % Hemolysis at >1490 µM | Human | Synthetic Cationic Antimicrobial Peptides | aqueous = α-Helix, 50%TFE = α-Helix | NA | ||
| 30702120 | 2019 | RRWV{d}RRV{d}RRWV{d}RRV{d}V{d}RV{d}V{d}RRWV{d}RR | D8 | Free | Free | Linear | Mix | None | 24 | Antibacterial | 0 ± 1 % Hemolysis at 50 μM | Human | Synthetic Peptide | NA | Non-hemolytic | ||
| 30842436 | 2019 | K-K-L-K-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 14 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 58 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 15 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 88 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala} | 16 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | 60 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-L{d}-K-{nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala} | 17 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | 40 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | {nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala}-K-L{d}-K-K | 18 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | Low hemolytic | ||
| 30842436 | 2019 | {nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala}-L{d}-K-K-K | 19 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | Low hemolytic | ||
| 30842436 | 2019 | {nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala}-K-L{d}-K-K | 20 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | Low hemolytic | ||
| 30842436 | 2019 | {nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala}-L{d}-K-K-K | 21 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | Low hemolytic | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-Y{d}-{nnr:(1-Nal)ala} | 25 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 53 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-{nnr:nle}-(1-Nal)ala-F{d}-(1-Nal)ala | 26 | Free | Free | Linear | Mix | nle = D-Norleucine, (1-Nal)Ala = 1-Naphthylalanine | 7 | Antimicrobial | 56 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-(2-Nal)ala-Y{d}-(2-Nal)ala | 28 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 64 % Hemolysis at 150 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-L-K-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 14 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 28 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 15 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 8 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala} | 16 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 18 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-L{d}-K-{nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala} | 17 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 8 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-Y{d}-{nnr:(1-Nal)ala} | 25 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 38 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(2-Nal)ala}-Y{d}-{nnr:(2-Nal)ala} | 28 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 10 % Hemolysis at 6 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-L-K-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 14 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 50 % Hemolysis at 128 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 15 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 50 % Hemolysis at 40 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(2-Nal)ala}-F{d}-{nnr:(2-Nal)ala} | 16 | Free | Free | Linear | Mix | (2-Nal)ala = D-2-Naphthylalanine | 7 | Antibacterial | 50 % Hemolysis at 118 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(1-Nal)ala}-Y{d}-{nnr:(1-Nal)ala} | 25 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 50 % Hemolysis at 138 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-{nnr:nle}-{nnr:(1-Nal)ala}-F{d}-{nnr:(1-Nal)ala} | 26 | Free | Free | Linear | Mix | nle = D-Norleucine, (1-Nal)Ala = 1-Naphthylalanine | 7 | Antimicrobial | 50 % Hemolysis at 63 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30842436 | 2019 | K-K-K-L{d}-{nnr:(2-Nal)ala}-Y{d}-{nnr:(2-Nal)ala} | 28 | Free | Free | Linear | Mix | (1-Nal)ala = D-1-Naphthylalanine | 7 | Antibacterial | 50 % Hemolysis at 50 µM | Human | Synthetic Peptide-Peptoid Hybrid | Random coil | NA | ||
| 30848594 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}{nnr:Dab}A{d}K{d}A{d}A{d}K{d}L{d}{nnr:Dab}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}{nnr:Dab} | D86(Lys¹-6 Dab-1) | Amidation | Acetylation | Linear | Mix | Dab = diaminobutyric acid | 26 | Antimicrobial | 50 % Hemolysis at >2000 μg/mL | Human | Synthetic Peptide | α-Helix | Low hemolytic | ||
| 30848594 | 2019 | K{d}L{d}{nnr:Dap}S{d}L{d}L{d}{nnr:Dap}T{d}L{d}S{d}{nnr:Dap}aK{d}A{d}A{d}K{d}L{d}{nnr:Dap}T{d}L{d}L{d}{nnr:Dap}A{d}L{d}S{d}{nnr:Dap} | D105(Lys¹-6 Dap-1) | Amidation | Acetylation | Linear | Mix | Dap = diaminopropionic acid | 26 | Antimicrobial | 50 % Hemolysis at >3000 μg/mL | Human | Synthetic Peptide | α-Helix | Low hemolytic | ||
| 30848594 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}{nnr:Dab}A{d}K{d}A{d}A{d}K{d}L{d}{nnr:Dab}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}S{d} | D102(Lys Ser26-5 Dab-1) | Amidation | Acetylation | Linear | Mix | Dab = diaminobutyric acid | 26 | Antimicrobial | 50 % Hemolysis at >2000 μg/mL | Human | Synthetic Peptide | α-Helix | Low hemolytic | ||
| 30848594 | 2019 | K{d}L{d}{nnr:Dab}S{d}L{d}L{d}{nnr:Dab}T{d}L{d}S{d}{nnr:Dab}A{d}A{d}A{d}A{d}A{d}L{d}{nnr:Dab}T{d}L{d}L{d}{nnr:Dab}A{d}L{d}S{d}{nnr:Dab} | D86(K13A/K16A) -(Lys¹-6 Dab-1) | Amidation | Acetylation | Linear | Mix | Dab = diaminobutyric acid | 26 | Antimicrobial | 50 % Hemolysis at 20 μg/mL | Human | Synthetic Peptide | α-Helix | NA | ||
| 30848594 | 2019 | K{d}L{d}{nnr:Dap}S{d}L{d}L{d}{nnr:Dap}T{d}L{d}S{d}{nnr:Dap}A{d}A{d}A{d}A{d}A{d}L{d}{nnr:Dap}T{d}L{d}L{d}{nnr:Dap}A{d}L{d}S{d}{nnr:Dap} | D105(K13A/K16A) -(Lys'-6 Dap-1) | Amidation | Acetylation | Linear | Mix | Dap = diaminopropionic acid | 26 | Antimicrobial | 50 % Hemolysis at 7.2 μg/mL | Human | Synthetic Peptide | α-Helix | NA | ||
| 30973929 | 2019 | EVL{d}ADL{d}V{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP1 | Amidation | Palmityl | Cyclic | Mix | None | 7 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 40 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EVL{d}DL{d}V{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP2 | Amidation | Palmityl | Cyclic | Mix | None | 6 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 100 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EVL{d}DL{d}{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP3 | Amidation | Palmityl | Cyclic | Mix | None | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 80 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EVL{d}L{d}{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP4 | Amidation | Palmityl | Cyclic | Mix | None | 4 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 5 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | Low hemolytic | ||
| 30973929 | 2019 | EVL{d}DL{d}{nt:Palmityl}{ct:Amid} | SLP5 | Amidation | Palmityl | Linear | Mix | None | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 25 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | KVL{d}KL{d}{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP6 | Amidation | Palmityl | Cyclic | Mix | None | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 90 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EVL{d}L{d}D{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP8 | Amidation | Palmityl | Cyclic | Mix | None | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 100 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EDVL{d}L{d}{cyc:N-C}{nt:Palmityl}{ct:Amid} | SLP9 | Amidation | Palmityl | Cyclic | Mix | None | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 50 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30973929 | 2019 | EVlDl{cyc:N-C}{nt:Heptaalkyl-biphenyl-acid}{ct:Amid} | SLP10 | Amidation | Heptaalkyl-biphenyl-acid | Cyclic | Mix | Heptaalkyl-biphenyl-acid | 5 | Anti-viral, Anti-PEDV(Porcine epidemic diarrhea virus) | 55 % Hemolysis at 10 μg/mL | Porcine | Synthetic Surfactin Lipopeptide Analogues | NA | NA | ||
| 30753486 | 2019 | VNWKKILGK{d}IIKVVK{ct:Amid} | LL-III/43 | Amidation | Free | Linear | Mix | None | 15 | Antibiofilm, Antifungal | 50 % Hemolysis at 400 µM | Human | Derived From Ll-Iii But With D-Leu | 30% TFE = α-Helix | NA | ||
| 30753486 | 2019 | GKWMKLL{d}KKILK{ct:Amid} | peptide VIII | Amidation | Free | Linear | Mix | None | 12 | Antibiofilm, Antifungal | 50 % Hemolysis at 400 µM | Human | Modified Hal-2 | 30% TFE = α-Helix | NA | ||
| 32641937 | 2019 | CGAGHVPC-YY{d}({nnr:GABA})F{d}YG{cyc:1-8} | MccJ25-derived peptide | Free | Free | Cyclic | Mix | GABA = gamma amino butyric acid | 14 | Antibacterial | 0.26 ± 0.01 % Hemolysis at 200 μM | Human | Bacteria Enterobacteriacea Mccj25- Derived Peptide | β-Sheet | Non-hemolytic | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17tF-W | Amidation | Free | Linear | Mix | X1 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 12.1 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17mF-W | Amidation | Free | Linear | Mix | X1 = 4-methylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 7.1 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | Low hemolytic | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17W2 | Amidation | Free | Linear | Mix | X1 = 4-methylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 8 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | Low hemolytic | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17tF2 | Amidation | Free | Linear | Mix | X1 = 4-t-butylphenylalanine, X2 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 32.5 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17B-tF | Amidation | Free | Linear | Mix | X1 = biphenylalanine, X2 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 30.2 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KD {nnr:X2}L{d}RKLV{ct:Amid} | 17BIPHE2 | Amidation | Free | Linear | Mix | X1 = biphenylalanine, X2 = biphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 61.5 % Hemolysis at 220 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17tF-W | Amidation | Free | Linear | Mix | X1 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at > 440 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17mF-W | Amidation | Free | Linear | Mix | X1 = 4-methylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at > 440 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17W2 | Amidation | Free | Linear | Mix | X1 = 4-methylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at > 440 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17tF2 | Amidation | Free | Linear | Mix | X1 = 4-t-butylphenylalanine, X2 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at > 440 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KDWL{d}RKLV{ct:Amid} | 17B-tF | Amidation | Free | Linear | Mix | X1 = biphenylalanine, X2 = 4-t-butylphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at > 440 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31319057 | 2019 | G{nnr:X1}KRL{d}VQRL{d}KD {nnr:X2}L{d}RKLV{ct:Amid} | 17BIPHE2 | Amidation | Free | Linear | Mix | X1 = biphenylalanine, X2 = biphenylalanine, l = D amino acid | 17 | Antimicrobial, Antibiofilm | 50 % Hemolysis at 180 μM | Human | Synthetic Ll-37 Derived Peptides | NA | NA | ||
| 31775224 | 2019 | IRP{d}IRP{d} | DIR1 | Free | Free | Linear | Mix | p = D-Proline | 6 | Antibacterial | ≥5 % Hemolysis at >128 µM | Human | Synthetic D-Proline Amps | 50% TFE = β-Sheet | Low hemolytic | ||
| 31775224 | 2019 | IRIRP{d}IRIRP{d} | DIR2 | Free | Free | Linear | Mix | p = D-Proline | 10 | Antibacterial | ≥5 % Hemolysis at >128 µM | Human | Synthetic D-Proline Amps | aqueous = unordered, 50% TFE = β-Sheet | Low hemolytic | ||
| 31775224 | 2019 | IRIRIRP{d}IRIRIRP{d} | DIR3 | Free | Free | Linear | Mix | p = D-Proline | 14 | Antibacterial, Anti-Inflammatory | ≥5 % Hemolysis at >128 µM | Human | Synthetic D-Proline Amps | aqueous = unordered, 50% TFE = β-Hairpin | Low hemolytic | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}W{d}S-{nnr:Dab}-{nnr:dab}-IEI-{nnr:aIle}-S | M1 (or M) | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), aile = D-aIle, Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | 10 % Hemolysis at 128 µg/ml | Rabbit | Tridecaptin M A Mud Bacterium, Paenibacillus Sp. M-152 | NA | Low hemolytic | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}W{d}S-{nnr:Dab}-{nnr:dab}-IEVV{d}S | M2 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | 2 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | Non-hemolytic | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}DFS-{nnr:Dab}-{nnr:dab}-IEIV{d}S | M5 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | 0 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | Non-hemolytic | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}W{d}S-{nnr:Dab}-{nnr:dab}-IEIV{d}S | M6 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | >15 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | NA | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}W{d}S-{nnr:Dab}-{nnr:dab}-VEI-{nnr:aIle}-S | M7 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), aile = D-aIle, Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | 1 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | Non-hemolytic | ||
| 31827113 | 2019 | G-{nnr:dab}-GS{d}DFS-{nnr:Dab}-{nnr:dab}-IEI-{nnr:aIle}-S | M8 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), aile = D-aIle, Dab = 2,4-diaminobutyric acid | 13 | Antibacterial | >9 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | Low hemolytic | ||
| 31827113 | 2019 | {nnr:dab}-FEI-{nnr:aIle}-S | M11 | Free | Free | Linear | Mix | dab = D-2,4-diaminobutyric acid (D-Dab), aile = D-aIle, Dab = 2,4-diaminobutyric acid | 6 | Antibacterial | 50 % Hemolysis at 128 µg/ml | Rabbit | Variants Of Tridecaptin M | NA | NA | ||
| 31676352 | 2019 | GLLK{d}{conj:C4}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C4 | Amidation | Free | Linear | Mix | C4 = C4 | 10 | Antibacterial, | 10 % Hemolysis at >256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}{conj:C6}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C6 | Amidation | Free | Linear | Mix | C6 = C6 | 10 | Antibacterial | 10 % Hemolysis at >256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}{conj:C8}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C8 | Amidation | Free | Linear | Mix | C8 = C8 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at >256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}{conj:C10}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C10 | Amidation | Free | Linear | Mix | C10 = C10 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at 256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}{conj:C12}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C12 | Amidation | Free | Linear | Mix | C12 = C12 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at 32 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 31676352 | 2019 | GLLK{d}{conj:C14}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C14 | Amidation | Free | Linear | Mix | C14 = C14 | 10 | Antibacterial | 10 % Hemolysis at 32 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 31676352 | 2019 | GLLK{d}{conj:C16}RIK{d}TLL{ct:Amid} | Ano-D4,7-4C16 | Amidation | Free | Linear | Mix | C16 = C16 | 10 | Antibacterial | 10 % Hemolysis at 16 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C4}TLL{ct:Amid} | Ano-D4,7-7C4 | Amidation | Free | Linear | Mix | C4 = C4 | 10 | Antibacterial | 10 % Hemolysis at >256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C6}TLL{ct:Amid} | Ano-D4,7-7C6 | Amidation | Free | Linear | Mix | C6 = C6 | 10 | Antibacterial | 10 % Hemolysis at >256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C8}TLL{ct:Amid} | Ano-D4,7-7C8 | Amidation | Free | Linear | Mix | C8 = C8 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at 256 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C10}TLL{ct:Amid} | Ano-D4,7-7C10 | Amidation | Free | Linear | Mix | C10 = C10 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at 128 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | Low hemolytic | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C12}TLL{ct:Amid} | Ano-D4,7-7C12 | Amidation | Free | Linear | Mix | C12 = C12 | 10 | Antibacterial, Antibiofilm | 10 % Hemolysis at 32 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C14}TLL{ct:Amid} | Ano-D4,7-7C14 | Amidation | Free | Linear | Mix | C14 = C14 | 10 | Antibacterial | 10 % Hemolysis at 16 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 31676352 | 2019 | GLLK{d}RIK{d}{conj:C16}TLL{ct:Amid} | Ano-D4,7-7C16 | Amidation | Free | Linear | Mix | C16 = C16 | 10 | Antibacterial | 10 % Hemolysis at 16 µM | mouse | Synthestic Amps With Conjugate Fatty Acid | 10 mM PBS (pH 7.4) = unordered, 30 mM SDS = α-helica | NA | ||
| 33479615 | 2020 | GHR{d}KPAQP | P1 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 50 % Hemolysis at >50 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | E{d}R{d}R{d}KPAQP | P2 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 0 % Hemolysis at 100 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | E{d}E{d}EKPAQP | P4 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 50 % Hemolysis at >50 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | E{d}F{d}R{d}TMVHPK | P5 | Free | Free | Linear | Mix | None | 9 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 0 % Hemolysis at 100 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | E{d}D{d}RKHAQA | P8 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 50 % Hemolysis at >40 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | K{d}EFHKTAQP | P9 | Free | Free | Linear | Mix | None | 9 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 50 % Hemolysis at >60 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | F{d}R{d}R{d}RPLRA | P13 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 0 % Hemolysis at 100 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | DD{d}H{d}KTAHQ | P14 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 50 % Hemolysis at >40 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | GW{d}RKPAQP | P16 | Free | Free | Linear | Mix | None | 8 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 0 % Hemolysis at 100 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 33479615 | 2020 | W{d}KR{d}LHHKPA | P18 | Free | Free | Linear | Mix | None | 9 | Neuraminidase inhibitor, Anti-influenza (H1N1 influenza virus), Antiviral | 0 % Hemolysis at 100 µM | Rabbit | Synthetic Peptide | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-K-L{d}-K-K | 3 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-L{d}-K-K-K | 4 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | <8 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-K-L{d}-K-K | 8 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 34.3 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-L{d}-K-K-K | 9 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 30.8 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-L{d}-K-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 10 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 11 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | 33.3 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala} | 12 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 43.5 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-l--{nnr:(1-nal)ala}-Y{d}-{nnr:(1-nal)ala} | 21 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, y = D-Tyr | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-Y{d}-{nnr:(2-nal)ala} | 24 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanine, y = D-Tyr, l = D-Leu | 7 | Antibacterial | 23.4 % Hemolysis at 150 µM | Human | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-K-L{d}-K-K | 3 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 10.5 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-L{d}-K-K-K | 4 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | <8 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-K-L{d}-K-K | 8 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 25.8 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-L{d}-K-K-K | 9 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 25.5 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-L{d}-K-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 10 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 36.3 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 11 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | 40.7 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala} | 12 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 50.2 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-l--{nnr:(1-nal)ala}-Y{d}-{nnr:(1-nal)ala} | 21 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, y = D-Tyr | 7 | Antibacterial | 19.9 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-Y{d}-{nnr:(2-nal)ala} | 24 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanine, y = D-Tyr, l = D-Leu | 7 | Antibacterial | 38.5 % Hemolysis at 150 µM | Canine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-K-L{d}-K-K | 3 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-L{d}-K-K-K | 4 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-K-L{d}-K-K | 8 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-L{d}-K-K-K | 9 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-L{d}-K-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 10 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 11 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | 11.3 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala} | 12 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | 17.9 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-l--{nnr:(1-nal)ala}-Y{d}-{nnr:(1-nal)ala} | 21 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, y = D-Tyr | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-Y{d}-{nnr:(2-nal)ala} | 24 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanine, y = D-Tyr, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Rat | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-K-L{d}-K-K | 3 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala}-L{d}-K-K-K | 4 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-K-L{d}-K-K | 8 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | {nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala}-L{d}-K-K-K | 9 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-L{d}-K-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 10 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(1-nal)ala}-F{d}-{nnr:(1-nal)ala} | 11 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial, Anticancer | 17.4 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-F{d}-{nnr:(2-nal)ala} | 12 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanin, f = D-phenylalanine, l = D-Leu | 7 | Antibacterial | <8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | Low hemolytic | ||
| 32764602 | 2020 | K-K-K-l--{nnr:(1-nal)ala}-Y{d}-{nnr:(1-nal)ala} | 21 | Free | Free | Linear | Mix | (1-nal)ala = D-1-napthylalanine, y = D-Tyr | 7 | Antibacterial | 16 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | NA | ||
| 32764602 | 2020 | K-K-K-L{d}-{nnr:(2-nal)ala}-Y{d}-{nnr:(2-nal)ala} | 24 | Free | Free | Linear | Mix | (2-nal)ala = D-2-napthylalanine, y = D-Tyr, l = D-Leu | 7 | Antibacterial | 29.8 % Hemolysis at 150 µM | Bovine | Synthetic Amps | NA | NA | ||
| 32590058 | 2020 | K{d}FW{d}SLLK{d}KALRLW{d}ANVL{ct:Amid} | CPF-2 | Amidation | Free | Linear | Mix | None | 17 | Antibiofilm, Antibacterial | 100 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = Random coil | NA | ||
| 32590058 | 2020 | K{d}F{d}W{d}S{d}L{d}L{d}K{d}K{d}A{d}L{d}R{d}L{d}W{d}A{d}N{d}V{d}L{d}{ct:Amid} | DCPF-2 | Amidation | Free | Linear | Mix | None | 17 | Antibacterial | 100 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = α-Helical (reverse Helical) | NA | ||
| 32590058 | 2020 | K{d}FW{d}SLLK{d}KAL{d}R{d}LW{d}KK{d}VL{ct:Amid} | CPF-2-1 | Amidation | Free | Linear | Mix | None | 17 | Antibacterial | 0 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = Random coil | Non-hemolytic | ||
| 32590058 | 2020 | K{d}FW{d}SLLK{d}KAL{d}R{d}LW{d}AK{d}VL{ct:Amid} | CPF-2-2 | Amidation | Free | Linear | Mix | None | 17 | Antibacterial | 0 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = Random coil | Non-hemolytic | ||
| 32590058 | 2020 | GFGSLLGKALRLW{d}KK{d}VL{ct:Amid} | CPF-14 | Amidation | Free | Linear | Mix | None | 17 | Antibacterial | ≥10 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = α-Helical | NA | ||
| 32590058 | 2020 | GFGSLLGKAL{d}R{d}LW{d}KK{d}VL{ct:Amid} | CPF-15 | Amidation | Free | Linear | Mix | None | 17 | Antibacterial | ≥75 % Hemolysis at 128 μg/mL | Mouse | Cpf-C1 Analogs (Tetraploid Frog Xenopus Clivii Peracca (Pipidae) ) | 50% TFE = Random coil | NA | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR | rR8 | Free | Free | Linear | Mix | None | 8 | Antimalarial | 0 % Hemolysis at 5 μM | Human | Derived From A Cell-Penetrating Peptide | Random coil | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR | rR8 | Free | Free | Linear | Mix | None | 8 | Antimalarial | 0 % Hemolysis at 10 μM | Human | Derived From A Cell-Penetrating Peptide | Random coil | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR | rR8 | Free | Free | Linear | Mix | None | 8 | Antimalarial | 0.8 % Hemolysis at 20 μM | Human | Derived From A Cell-Penetrating Peptide | Random coil | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR | rR8 | Free | Free | Linear | Mix | None | 8 | Antimalarial | 1.3 % Hemolysis at 40 μM | Human | Derived From A Cell-Penetrating Peptide | Random coil | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR-KKKKKKKKKYYKYKKKEKEKK | rR8-JR21 | Free | Free | Linear | Mix | None | 29 | Antimalarial | 0 % Hemolysis at 5 μM | Human | Combination Of Rr8 And Jr21 Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR-KKKKKKKKKYYKYKKKEKEKK | rR8-JR21 | Free | Free | Linear | Mix | None | 29 | Antimalarial | 0 % Hemolysis at 10 μM | Human | Combination Of Rr8 And Jr21 Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR-KKKKKKKKKYYKYKKKEKEKK | rR8-JR21 | Free | Free | Linear | Mix | None | 29 | Antimalarial | 0.8 % Hemolysis at 20 μM | Human | Combination Of Rr8 And Jr21 Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR-KKKKKKKKKYYKYKKKEKEKK | rR8-JR21 | Free | Free | Linear | Mix | None | 29 | Antimalarial | 1.3 % Hemolysis at 40 μM | Human | Combination Of Rr8 And Jr21 Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR- DDDDEEEDDFVYFNFNKEKEE | rR8-JR helix | Free | Free | Linear | Mix | None | 29 | NA | 0 % Hemolysis at 5 μM | Human | Combination Of Rr8 And Jr Helix Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR- DDDDEEEDDFVYFNFNKEKEE | rR8-JR helix | Free | Free | Linear | Mix | None | 29 | NA | 0 % Hemolysis at 10 μM | Human | Combination Of Rr8 And Jr Helix Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR- DDDDEEEDDFVYFNFNKEKEE | rR8-JR helix | Free | Free | Linear | Mix | None | 29 | NA | 0.8 % Hemolysis at 20 μM | Human | Combination Of Rr8 And Jr Helix Sequences | Random coil and Helical | Non-hemolytic | ||
| 32673701 | 2020 | R{d}RR{d}RR{d}RRR- DDDDEEEDDFVYFNFNKEKEE | rR8-JR helix | Free | Free | Linear | Mix | None | 29 | NA | 1.1 % Hemolysis at 40 μM | Human | Combination Of Rr8 And Jr Helix Sequences | Random coil and Helical | Non-hemolytic | ||
| 32786271 | 2020 | K{d}FFK{d}R{d}LLK{d}SVR{d}R{d}AVK{d}K{d}FR{d}K{d}{ct:Amid} | HC1-D1 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial, Anti-inflammatory, Antibiofilm | 28 % Hemolysis at 50 μM | Mouse | Hc-Cath Derivatives | water = Random coil, 60 mM SDS solution = Random coil | NA | ||
| 32786271 | 2020 | KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL | Hc-CATH | Free | Free | Linear | Mix | None | 30 | Antimicrobial, Anti-inflammatory, Antibiofilm | 37 % Hemolysis at 50 μM | Mouse | Hc-Cath Derivatives | amphipathic α-Helical | NA | ||
| 32786271 | 2020 | K{d}FFK{d}R{d}LLK{d}SVR{d}R{d}AVK{d}K{d}FR{d}K{d}{ct:Amid} | HC1-D1 | Amidation | Free | Linear | Mix | None | 19 | Antimicrobial, Anti-inflammatory, Antibiofilm | 9 % Hemolysis at 50 μM | Human | Hc-Cath Derivatives | water = Random coil, 60 mM SDS solution = Random coil | NA | ||
| 32786271 | 2020 | KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL | Hc-CATH | Free | Free | Linear | Mix | None | 30 | Antimicrobial, Anti-inflammatory, Antibiofilm | 16 % Hemolysis at 50 μM | Human | Hc-Cath Derivatives | amphipathic α-Helical | NA | ||
| 32967333 | 2020 | AL{d}WK{d}K{d}L{d}L{d}K{d}K{d}-{nnr:Cha}{ct:Amid} | DMPC-10B | Amidation | Free | Linear | Mix | Cha = Cyclohexanylalanine | 10 | Antibacterial, Antibiofilm | 0 % Hemolysis at 128 μM | Horse | Modificaiton Of Dmpc-10A | TFE = α-Helix | Non-hemolytic | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}L{nt:C16} | C16-fXXL | Free | C16 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine | 4 | Antibacterial | ~10 % Hemolysis at 5 μg/mL | Horse | Synthetic Lipopeptide | NA | NA | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}L{nt:C14} | C14-fXXL | Free | C14 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine | 4 | Antibacterial | ~10 % Hemolysis at 5 μg/mL | Horse | Synthetic Lipopeptide | NA | NA | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}{nnr:L}{nt:C12} | C12-fXXL | Free | C12 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine, L = L-leucine | 4 | Antibacterial | <5 % Hemolysis at 5 μg/mL | Horse | Synthetic Lipopeptide | NA | NA | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}L{nt:C16} | C16-fXXL | Free | C16 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine | 4 | Antibacterial | <5 % Hemolysis at 5 μg/mL | Sheep | Synthetic Lipopeptide | NA | NA | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}L{nt:C14} | C14-fXXL | Free | C14 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine | 4 | Antibacterial | ~10 % Hemolysis at 5 μg/mL | Sheep | Synthetic Lipopeptide | NA | NA | ||
| 33085895 | 2020 | F{d}{nnr:X}{nnr:X}{nnr:L}{nt:C12} | C12-fXXL | Free | C12 | Linear | Mix | X = L-2,4-diaminobutyric acid, f = D-phenylalanine, L = L-leucine | 4 | Antibacterial | 0 % Hemolysis at 5 μg/mL | Sheep | Synthetic Lipopeptide | NA | Non-hemolytic | ||
| 33296183 | 2021 | FLK{nnr:D-2-NaI}LKKLL{ct:Amid} | Feleucin-K56 | Amidation | Free | Linear | Mix | D-2-nal = D-2-nal | 9 | Antibacterial | ≥10 % Hemolysis at 128 μg/mL | Mouse | Feleucin-K3 Analogues (Frog Bombina Orientalis) | TFE = α-Helix | Low hemolytic | ||
| 33469079 | 2021 | RK{d}RW{d}WV{d}VK{d}RK{d}WW{d}V{ct:Amid} | AS01 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 7.24 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | NA | ||
| 33469079 | 2021 | RK{d}RW{d}LW{d}LK{d}RK{d}WL{d}W{ct:Amid} | AS02 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 0 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | Non-hemolytic | ||
| 33469079 | 2021 | KK{d}KW{d}WV{d}KK{d}KW{d}WV{d}V{ct:Amid} | AS03 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 0 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | Non-hemolytic | ||
| 33469079 | 2021 | WW{d}KK{d}KV{d}WV{d}KK{d}KW{d}W{ct:Amid} | AS04 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 0.25 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | Non-hemolytic | ||
| 33469079 | 2021 | KK{d}KV{d}VV{d}KK{d}KV{d}VW{d}K{ct:Amid} | AS06 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial | 0 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | Non-hemolytic | ||
| 33469079 | 2021 | WL{d}WL{d}WL{d}WV{d}KK{d}AK{d}AK{d}K{ct:Amid} | AS08 | Amidation | Free | Linear | Mix | None | 15 | Antimicrobial | 1.46 % Hemolysis at 8 µM | Human | Synthetic Syndiotactic Polypeptides | Helical | NA | ||
| 34220763 | 2021 | WK{d}K{d}L{d}K{d}K{d}L{d}L{d}K{d}K{d}L{d}K{d}K{d}L{d}{nt:Acet}{ct:Amid} | pepdD2 | Amidation | Acetylation | Linear | Mix | None | 14 | Antibacterial, Antibiofilm | 2.9 % Hemolysis at 256 μg/mL | Rat | De Novo Designed Peptide | NA | Low hemolytic | ||
| 34205705 | 2021 | KKLF{d}KKILKYL{nt:C5H11CO}{ct:Amid} | BP472 | Amidation | C5H11CO | Linear | Mix | None | 11 | Antifungal, Antibacterial | 78 ± 5 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KK({nnr:COC3H7})IL{d}KYL{d}{nt:Acet}{ct:Amid} | BP473 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 84 ± 11 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KKIK({nnr:COC3H7})KYL{d}{nt:Acet}{ct:Amid} | BP474 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 0 ± 0 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}KK({nnr:COC3H7})L{d}{nt:Acet}{ct:Amid} | BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 0 ± 0 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | α-Helical | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}KYK({nnr:COC11H23}){nt:Acet}{ct:Amid} | BP476 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 94 ± 10 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}k({nnr:COC5H11})KKIL{d}KYL{d}{nt:Acet}{ct:Amid} | BP484 | Amidation | Acetylation | Linear | Mix | COC5H11 = hexanoyl | 11 | Antifungal, Antibacterial | 10 ± 2 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}{d}KKIL{d}KYL{d}{nt:C3H7CO}{ct:Amid} | BP485 | Amidation | C3H7CO | Linear | Mix | None | 11 | Antifungal, Antibacterial | 24 ± 9 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KK({nnr:COC3H7})L{d}F{d}KKIL{d}KYL{d}{nt:Acet}{ct:Amid} | BP486 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 14 ± 5 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}k({nnr:COC11H23})KKIL{d}KYL{d}{nt:Acet}{ct:Amid} | BP488 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 86 ± 14 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KKK({nnr:COC11H23})L{d}KYL{d}{nt:Acet}{ct:Amid} | BP489 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 100 ± 6 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KKIK({nnr:COC11H23})KYL{d}{nt:Acet}{ct:Amid} | BP490 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 100 ± 6 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KKK({nnr:COC5H11})L{d}KYL{d}{nt:Acet}{ct:Amid} | BP494 | Amidation | Acetylation | Linear | Mix | COC5H11 = hexanoyl | 11 | Antifungal, Antibacterial | 0.2 ± 0.2 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}KYK({nnr:COC5H11}){nt:Acet}{ct:Amid} | BP495 | Amidation | Acetylation | Linear | Mix | COC5H11 = hexanoyl | 11 | Antifungal, Antibacterial | 0.6 ± 1 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}KYK({nnr:COC3H7}){nt:Acet}{ct:Amid} | BP496 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 1 ± 1 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | Non-hemolytic | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}K({nnr:COC11H23})YL{d}{nt:Acet}{ct:Amid} | BP497 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 100 ± 2 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}K({nnr:COC3H7})KIL{d}KYL{d}{nt:Acet}{ct:Amid} | BP498 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 21 ± 3 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKL{d}F{d}KKIL{d}K({nnr:COC3H7})YL{d}{nt:Acet}{ct:Amid} | BP499 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antifungal, Antibacterial | 11 ± 1 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34205705 | 2021 | KKK({nnr:COC11H23})F{d}KKIL{d}KYL{d}{nt:Acet}{ct:Amid} | BP500 | Amidation | Acetylation | Linear | Mix | COC11H23 = lauroyl | 11 | Antifungal, Antibacterial | 71 ± 8 % Hemolysis at 256 μM | Horse | Synthetic Lipopeptides | NA | NA | ||
| 34342438 | 2021 | {nnr:O}P{d}FT{nnr:O}AQWFAIQHISP{nnr:O}TIAM{nnr:O}AINNY{nnr:O}W{nnr:O} | [Orn,1D-Pro2] analog | Free | Free | Linear | Mix | O = L-Ornithine, p = D-Proline | 30 | Antibacterial | 1.1 ± 0.9 % Hemolysis at 250 μM | Horse | Hecp30 Analogs | aqueous = Random coil, SDS micelles (1 mM) = α-Helical | Low hemolytic | ||
| 34342438 | 2021 | {nnr:o}P{d}FT{nnr:O}AQWFAIQHISP{nnr:O}TIAM{nnr:O}AINNY{nnr:O}W{nnr:O} | [D-Orn,1D-Pro2] analog | Free | Free | Linear | Mix | o = D-Ornithine, p = D-Proline | 30 | Antibacterial | 3.6 ± 0.7 % Hemolysis at 250 μM | Horse | Hecp30 Analogs | aqueous = Random coil, SDS micelles (1 mM) = α-Helical | Low hemolytic | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKSI{ct:Amid} | HP1404 T1-D | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial, Antibiofilm | 0.3 ± 0.3 % Hemolysis at 150 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKK{d}I{d}{ct:Amid} | HP1404 T1-E | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 0.8 ± 0.4 % Hemolysis at 150 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{ct:Amid} | BP525 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 3.1 ± 1.0 % Hemolysis at 150 μM | Horse | Synthetic Peptide | NA | Low hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C3H7CO}{ct:Amid} | BP526 | Amidation | C3H7CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 8.3 ± 0.7 % Hemolysis at 150 μM | Horse | Synthetic Peptide | NA | Low hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C5H11CO}{ct:Amid} | BP527 | Amidation | C5H11CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 62.2 ± 4.4 % Hemolysis at 150 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C11H23CO}{ct:Amid} | BP528 | Amidation | C11H23CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 92.1 ± 5.7 % Hemolysis at 150 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:HOC11H22CO}{ct:Amid} | BP529 | Amidation | HOC11H22CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 7.2 ± 0.3 % Hemolysis at 150 μM | Horse | Synthetic Peptide | NA | Low hemolytic | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKSI{ct:Amid} | HP1404 T1-D | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial, Antibiofilm | 0.8 ± 1.1 % Hemolysis at 250 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKK{d}I{d}{ct:Amid} | HP1404 T1-E | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 0.7 ± 0.4 % Hemolysis at 250 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{ct:Amid} | BP525 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 3.8 ± 0.8 % Hemolysis at 250 μM | Horse | Synthetic Peptide | NA | Low hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C3H7CO}{ct:Amid} | BP526 | Amidation | C3H7CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 20.4 ± 0.7 % Hemolysis at 250 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C5H11CO}{ct:Amid} | BP527 | Amidation | C5H11CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 73.6 ± 1.1 % Hemolysis at 250 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C11H23CO}{ct:Amid} | BP528 | Amidation | C11H23CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 96.6 ± 3.1 % Hemolysis at 250 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:HOC11H22CO}{ct:Amid} | BP529 | Amidation | HOC11H22CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 12.5 ± 0.6 % Hemolysis at 250 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKSI{ct:Amid} | HP1404 T1-D | Amidation | Free | Linear | Mix | None | 12 | Antimicrobial, Antibiofilm | 1.3 ± 0.2 % Hemolysis at 375 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILK{d}KLL{d}K{d}K{d}VKK{d}I{d}{ct:Amid} | HP1404 T1-E | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 1.5 ± 0.3 % Hemolysis at 375 μM | Horse | Synthetic Peptides | NA | Non-hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{ct:Amid} | BP525 | Amidation | Free | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 10.0 ± 5.9 % Hemolysis at 375 μM | Horse | Synthetic Peptide | NA | Low hemolytic | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C3H7CO}{ct:Amid} | BP526 | Amidation | C3H7CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 46.8 ± 3.3 % Hemolysis at 375 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C5H11CO}{ct:Amid} | BP527 | Amidation | C5H11CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 100.0 ± 2.6 % Hemolysis at 375 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:C11H23CO}{ct:Amid} | BP528 | Amidation | C11H23CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 99.1 ± 8.0 % Hemolysis at 375 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34819923 | 2021 | ILPF{d}KF{d}PF{d}F{d}PF{d}RR{nt:HOC11H22CO}{ct:Amid} | BP529 | Amidation | HOC11H22CO | Linear | Mix | None | 13 | Antimicrobial, Antibiofilm | 39.0 ± 1.1 % Hemolysis at 375 μM | Horse | Synthetic Peptide | NA | NA | ||
| 34959645 | 2021 | G{nnr:X}KRlVQRlKD{nnr:X}LRNLV{ct:Amid} | 17BIPHE2 | Amidation | Free | Linear | Mix | X = biphenylalanines | 17 | Antibacterial, Antibiofilm | 50 % Hemolysis at ~200 μM | Human | Ll-37 Derived Peptide | PBS = distorted, 60mMSDS = Helical | NA | ||
| 34977576 | 2021 | {nnr:B}K{d}KL{d}LK{d}CL{d}KC{d}LL{d}{cyc:7-10} | bp67 | Free | Free | Bicyclic | Mix | B = 3,5-bis(methylene)toluoyl | 12 | Antibacterial | MHC at >2000 μg/ml | Human | Synthetic Peptide | 5 mM DPC = α-Helical | Low hemolytic | ||
| 34977576 | 2021 | {nnr:B}KKLLKC{d}LKC{d}LL{cyc:7-10} | bp68 | Free | Free | Bicyclic | Mix | B = 3,5-bis(methylene)toluoyl | 12 | Antibacterial | MHC at 16.6 μg/ml | Human | Synthetic Peptide | 5 mM DPC = α-Helical | NA | ||
| 34977576 | 2021 | {nnr:B}K{d}K{d}LLK{d}CLK{d}CLL{cyc:7-10} | bp69 | Free | Free | Bicyclic | Mix | B = 3,5-bis(methylene)toluoyl | 12 | Antibacterial | MHC at 16.6 μg/ml | Human | Synthetic Peptide | 5 mM DPC = α-Helical | NA | ||
| 34977576 | 2021 | K{d}K{d}LLK{d}LLK{d}LLL | ln69 | Free | Free | Linear | Mix | None | 12 | Antibacterial | MHC at 1000 μg/ml | Human | Synthetic Peptide | 5 mM DPC = α-Helical | Low hemolytic | ||
| 34977576 | 2021 | {nnr:Tol}-K{d}K{d}LLK{d}-{nnr:Cm}-LK{d}-{nnr:Cm}-LL | ln69b | Free | Free | Linear | Mix | Tol = toluoyl group, Cm = S-methyl cysteine | 12 | Antibacterial | MHC at 1000 μg/ml | Human | Synthetic Peptide | 5 mM DPC = α-Helical | Low hemolytic | ||
| 35145500 | 2022 | R{d}RLFRRILRWL{ct:Amid} | RW-BP100-1D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 4.61 ± 0.47 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RR{d}LFRRILRWL{ct:Amid} | RW-BP100-2D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 4.83 ± 1.08 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRL{d}FRRILRWL{ct:Amid} | RW-BP100-3D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 3.49 ± 0.76 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLF{d}RRILRWL{ct:Amid} | RW-BP100-4D* | Amidation | Free | Linear | Mix | None | 11 | Antibacterial, Antifungal, Antibiofilm | 0.11 ± 0.19 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFR{d}RILRWL{ct:Amid} | RW-BP100-5D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.26 ± 0.54 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRR{d}ILRWL{ct:Amid} | RW-BP100-6D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 2.33 ± 1.51 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRI{d}LRWL{ct:Amid} | RW-BP100-7D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 0.53 ± 1.12 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRIL{d}RWL{ct:Amid} | RW-BP100-8D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 0.91 ± 0.38 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILR{d}WL{ct:Amid} | RW-BP100-9D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 0.63 ± 0.24 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILRW{d}L{ct:Amid} | RW-BP100-10D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 0.31 ± 0.37 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILRWL{d}{ct:Amid} | RW-BP100-11D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 0.65 ± 0.60 % Hemolysis at 50 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | R{d}RLFRRILRWL{ct:Amid} | RW-BP100-1D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 5.49 ± 0.23 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RR{d}LFRRILRWL{ct:Amid} | RW-BP100-2D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 5.99 ± 0.79 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRL{d}FRRILRWL{ct:Amid} | RW-BP100-3D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 4.04 ± 0.20 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLF{d}RRILRWL{ct:Amid} | RW-BP100-4D* | Amidation | Free | Linear | Mix | None | 11 | Antibacterial, Antifungal, Antibiofilm | 3.69 ± 0.01 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFR{d}RILRWL{ct:Amid} | RW-BP100-5D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 2.49 ± 0.72 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRR{d}ILRWL{ct:Amid} | RW-BP100-6D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 3.25 ± 0.23 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRI{d}LRWL{ct:Amid} | RW-BP100-7D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.11 ± 0.19 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRIL{d}RWL{ct:Amid} | RW-BP100-8D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.38 ± 0.58 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILR{d}WL{ct:Amid} | RW-BP100-9D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.53 ± 0.09 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILRW{d}L{ct:Amid} | RW-BP100-10D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.28 ± 0.19 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | RRLFRRILRWL{d}{ct:Amid} | RW-BP100-11D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 1.42 ± 0.15 % Hemolysis at 100 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | Low hemolytic | ||
| 35145500 | 2022 | R{d}RLFRRILRWL{ct:Amid} | RW-BP100-1D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 39.81 ± 0.20 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RR{d}LFRRILRWL{ct:Amid} | RW-BP100-2D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 39.16 ± 1.75 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRL{d}FRRILRWL{ct:Amid} | RW-BP100-3D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 38.13 ± 3.12 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLF{d}RRILRWL{ct:Amid} | RW-BP100-4D* | Amidation | Free | Linear | Mix | None | 11 | Antibacterial, Antifungal, Antibiofilm | 18.75 ± 0.42 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFR{d}RILRWL{ct:Amid} | RW-BP100-5D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 29.72 ± 0.94 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRR{d}ILRWL{ct:Amid} | RW-BP100-6D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 32.57 ± 1.20 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRI{d}LRWL{ct:Amid} | RW-BP100-7D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 16.17 ± 3.36 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRIL{d}RWL{ct:Amid} | RW-BP100-8D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 26.19 ± 0.10 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILR{d}WL{ct:Amid} | RW-BP100-9D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 18.14 ± 0.20 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILRW{d}L{ct:Amid} | RW-BP100-10D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 19.20 ± 2.16 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILRWL{d}{ct:Amid} | RW-BP100-11D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 17.36 ± 1.92 % Hemolysis at 150 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | R{d}RLFRRILRWL{ct:Amid} | RW-BP100-1D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 52.88 ± 3.06 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RR{d}LFRRILRWL{ct:Amid} | RW-BP100-2D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 62.12 ± 6.27 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRL{d}FRRILRWL{ct:Amid} | RW-BP100-3D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 55.73 ± 5.27 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLF{d}RRILRWL{ct:Amid} | RW-BP100-4D* | Amidation | Free | Linear | Mix | None | 11 | Antibacterial, Antifungal, Antibiofilm | 48.55 ± 2.53 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFR{d}RILRWL{ct:Amid} | RW-BP100-5D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 51.41 ± 4.64 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRR{d}ILRWL{ct:Amid} | RW-BP100-6D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 55.81 ± 2.87 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRI{d}LRWL{ct:Amid} | RW-BP100-7D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 45.65 ± 5.13 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRIL{d}RWL{ct:Amid} | RW-BP100-8D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 50.11 ± 3.17 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILR{d}WL{ct:Amid} | RW-BP100-9D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 45.18 ± 2.41 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILRW{d}L{ct:Amid} | RW-BP100-10D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 45.08 ± 4.70 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 35145500 | 2022 | RRLFRRILRWL{d}{ct:Amid} | RW-BP100-11D | Amidation | Free | Linear | Mix | None | 11 | Antibacterial | 46.97 ± 6.45 % Hemolysis at 300 μg/mL | Sheep | Rw-Bp-100 Analogue | NA | NA | ||
| 36350889 | 2022 | GRKSAKIGKRAKRIVQRIKDF{d}LR{nt:Acet}{ct:Amid} | DLL37-1 | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acid | 23 | Antibacterial, Antibiofilm | ≤5 % Hemolysis at 1.5 μM | Human | Ll37 Analogous | α-Helical | NA | ||
| 36350889 | 2022 | GRKSAKIGKRAKRIVQRIKDF{d}LR{nt:Acet}{ct:Amid} | DLL37-1 | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acid | 23 | Antibacterial, Antibiofilm | ≤5 % Hemolysis at 2.5 μM | Human | Ll37 Analogous | α-Helical | NA | ||
| 36350889 | 2022 | GRKSAKIGKRAKRIVQRIKDF{d}LR{nt:Acet}{ct:Amid} | DLL37-1 | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acid | 23 | Antibacterial, Antibiofilm | ≤5 % Hemolysis at 5 μM | Human | Ll37 Analogous | α-Helical | NA | ||
| 36350889 | 2022 | GRKSAKIGKRAKRIVQRIKDF{d}LR{nt:Acet}{ct:Amid} | DLL37-1 | Amidation | Acetylation | Linear | Mix | lowercase letters correspond to D-amino acid | 23 | Antibacterial, Antibiofilm | ≤20 % Hemolysis at 10 μM | Human | Ll37 Analogous | α-Helical | NA | ||
| 36442155 | 2022 | R{d}R{d}R{d}R{d}WWWW{cyc:N-C} | 4a | Free | Free | Cyclic | Mix | r = D-Arginine | 8 | Antibacterial | 50 % Hemolysis at 110 μg/mL | Human | Synthetic Cyclic Peptide | NA | NA | ||
| 36555393 | 2022 | GIGAVLKVLTTGLPALISWIKRKRQQGGGGSK{d}L{d}A{d}K{d}L{d}A{d}K{d}K{d}L{d}A{d}K{d}L{d}A{d}K{d}{nt:(FITC)-Ahx = Fluorescein isothiocyanate} | melittin-dKLA | Free | (FITC)-Ahx = Fluorescein isothiocyanate | Linear | Mix | None | 45 | NA | 100 % Hemolysis at 40 μM | Mouse | Modified Melittin | NA | NA | ||
| 36555393 | 2022 | VLTTGLPALISWIKRKRQQGGGGSK{d}L{d}A{d}K{d}L{d}A{d}K{d}K{d}L{d}A{d}K{d}L{d}A{d}K{d}{nt:(FITC)-Ahx = Fluorescein isothiocyanate} | melittin-dKLA 8-26 | Free | (FITC)-Ahx = Fluorescein isothiocyanate | Linear | Mix | None | 38 | Anticancer | <5 % Hemolysis at 40 μM | Mouse | Modified Melittin | NA | Non-hemolytic | ||
| 37251186 | 2023 | KKKKKGIGF{d}LAF{d}GAFVILKKKK{ct:Amid} | MSI-Seg-F2F | Amidation | Free | Linear | Mix | None | 22 | Antibacterial | 8.1 ± 3.2 % Hemolysis at 100 µM | Pig | Msi-78 Analogues | LPC and LPS = β-Sheet | NA | ||
| 37446618 | 2023 | YA{d}FGYPSGHFM | LENART01 | Free | Free | Linear | Mix | a = D-alanine | 11 | Antibacterial | 4.8 % Hemolysis at 200 µM (1 hour) | Human | Opioid–Ranatensin Hybrid Peptide | NA | Low hemolytic | ||
| 37446618 | 2023 | YA{d}FGYPSGHFM | LENART01 | Free | Free | Linear | Mix | a = D-alanine | 11 | Antibacterial | 8.3 % Hemolysis at 200 µM (2 hour) | Human | Opioid–Ranatensin Hybrid Peptide | NA | Low hemolytic | ||
| 37446618 | 2023 | YA{d}FGYPSGHFM | LENART01 | Free | Free | Linear | Mix | a = D-alanine | 11 | Antibacterial | 16.4 % Hemolysis at 200 µM (4 hour) | Human | Opioid–Ranatensin Hybrid Peptide | NA | Low hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C2} | PE-2C-C2-DH | Free | C2 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C3} | PE-2C-C3-DH | Free | C3 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C4} | PE-2C-C4-DH | Free | C4 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C5} | PE-2C-C5-DH | Free | C5 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C6} | PE-2C-C6-DH | Free | C6 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C7} | PE-2C-C7-DH | Free | C7 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:C8} | PE-2C-C8-DH | Free | C8 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:6-MC7} | PE-2C-6-MC7-DH | Free | 6-MC7 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:6-MC8} | PE-2C-6-MC8-DH | Free | 6-MC8 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at >1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 36941353 | 2023 | {nnr:Dab}-T-{nnr:Dab}-[C-{nnr:Dab}-L{d}-L-{nnr:Dab}-{nnr:Dab}-C]{cyc:4-10}{nt:LB-8} | PE-2C-LB-8-DH) | Free | LB-8 | Cyclic | Mix | Dab = L-2,4-diaminobutyric acid | 10 | Antibacterial | 0 % Hemolysis at 1500 μg/mL | Rabbit | Synthetic Cyclic Peptide | NA | Non-hemolytic | ||
| 35216177 | 2022 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3 , DLeu9 ] TL | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial, Antibiofilm | ∼50 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3 , DLeu9 ] TL | Amidation | Free | Linear | Mix | l = D-Leucine | 13 | Antibacterial, Antibiofilm | ∼25 % Hemolysis at 50 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}GRIL{ct:Amid} | [Pro3,DLeu9] TL (TL1) | Amidation | Free | Linear | Mix | l=D-Leu | 13 | Antibacterial, Antibiofilm | 60 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}PRIL{ct:Amid} | [Pro3,DLeu9,Pro10] TL (TL2) | Amidation | Free | Linear | Mix | l=D-Leu | 14 | Antibacterial, Antibiofilm | 60 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}P{d}RIL{ct:Amid} | [Pro3,DLeu9,DPro10] TL (TL3) | Amidation | Free | Linear | Mix | l=D-Leu, p = D-Pro | 14 | Antibacterial, Antibiofilm | 20 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}{nnr:O}RIL{ct:Amid} | [Pro3,DLeu9,Hyp10] TL (TL4) | Amidation | Free | Linear | Mix | l=D-Leu, O = Hyp = hydroxyproline | 14 | Antibacterial, Antibiofilm | 80 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}{nnr:o}RIL{ct:Amid} | [Pro3,DLeu9,DHyp10] TL (TL5) | Amidation | Free | Linear | Mix | l=D-Leu, o = D-Hyp = hydroxyproline | 14 | Antibacterial, Antibiofilm | 20 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}{nnr:N=Nle}RIL{ct:Amid} | [Pro3,DLeu9,Nle10] TL (TL6) | Amidation | Free | Linear | Mix | l=D-Leu, N = Nle | 14 | Antibacterial, Antibiofilm | 60 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}{nnr:n=D-Nle}RIL{ct:Amid} | [Pro3,DLeu9,DNle10] TL (TL7) | Amidation | Free | Linear | Mix | l=D-Leu, n = D-Nle | 14 | Antibacterial, Antibiofilm | 40 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}KRIL{ct:Amid} | [Pro3,DLeu9,Lys10] TL (TL8) | Amidation | Free | Linear | Mix | l=D-Leu | 14 | Antibacterial, Antibiofilm | 80 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}K{d}RIL{ct:Amid} | [Pro3,DLeu9,DLys10] TL (TL9) | Amidation | Free | Linear | Mix | l=D-Leu, k = D-Lys | 14 | Antibacterial, Antibiofilm | 40 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}WRIL{ct:Amid} | [Pro3,DLeu9,Trp10] TL (TL10) | Amidation | Free | Linear | Mix | l=D-Leu | 14 | Antibacterial, Antibiofilm | 60 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFL{d}W{d}RIL{ct:Amid} | [Pro3,DLeu9,DTrp10] TL (TL11) | Amidation | Free | Linear | Mix | l=D-Leu, w = D-Trp | 14 | Antibacterial, Antibiofilm | 80 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35216177 | 2022 | FVPWFSKFl{nnr:Aic}RIL{ct:Amid} | [Pro3,DLeu9,Aic10] TL (TL12) | Amidation | Free | Linear | Mix | Aic = 2-aminoindane-2-carboxylic acid | 14 | Antibacterial, Antibiofilm | 100 % Hemolysis at 100 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 2.812 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 2.812 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 2.812 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 1±0.62 % Hemolysis at 5.625 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 5.625 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 5.625 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 7±0.55 % Hemolysis at 11.25 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | <1 % Hemolysis at 11.25 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 1.8±0.9 % Hemolysis at 11.25 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 52.74 ± 5.94 % Hemolysis at 22.5 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 2.88 ± 1.24 % Hemolysis at 22.5 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 2 ± 0.94 % Hemolysis at 22.5 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 55.07 ± 5.23 % Hemolysis at 45 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 18.18 ± 7.65 % Hemolysis at 45 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 7.49 ± 1.20 % Hemolysis at 45 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 58.93 ± 6.02 % Hemolysis at 90 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 42.93 ± 4.75 % Hemolysis at 90 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 44.69 ± 3.73 % Hemolysis at 90 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 61.64 ± 13.83 % Hemolysis at 180 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 47.60 ± 7.88 % Hemolysis at 180 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 57.01 ± 8.50 % Hemolysis at 180 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 64.71 ± 11.34 % Hemolysis at 360 µM | Human | Synthetic | α-Helix | NA | ||
| 35092568 | 2022 | FLSA{d}IVGMLGKLF{ct:Amid} | [G4a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 51.15 ± 10.41 % Hemolysis at 360 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35092568 | 2022 | FLSGIVA{d}MLGKLF{ct:Amid} | [G7a]-SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antibacterial, Antibiofilm | 58.97 ± 5.51 % Hemolysis at 360 µM | Human | Synthetic | α-Helix | Low hemolytic | ||
| 35740884 | 2022 | FLPLIIGALSSLLPKI{d}F{ct:Amid} | Temporin-PKE-i | Amidation | Free | Linear | Mix | i = D-Isoleucine | 17 | Antimicrobial, Cytotoxic | 50 % Hemolysis at 68.37 µM | Horse | Synthetic Analogues Of Temporin-Pke | α-Helix | Low hemolytic | ||
| 35740884 | 2022 | FLPLI{d}I{d}GALSSLLPKI{d}F{ct:Amid} | Temporin-PKE-3i | Amidation | Free | Linear | Mix | i = D-Isoleucine | 17 | Antimicrobial, Cytotoxic | 50 % Hemolysis at 64 µM | Horse | Synthetic Analogues Of Temporin-Pke | α-Helix | Low hemolytic | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a] SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antimicrobial, Antiproliferative | 50 % Hemolysis at 43.66 ± 1.01 µM | Human | Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLFK-FLSGIVGMLDAKLF{ct:Amid} | [G10a]2 SHa | Amidation | Free | Linear | Mix | a = D-alanine, Linked b/w Phe26 and Lys40 and Lys41 and Phe39 | 27 | Antimicrobial, Antiproliferative | 50 % Hemolysis at 11.55 ± 0.38 µM | Human | Dendrimeric Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLFKK-FLSGIVGMLDAKLF-FLSGIVGMLDAKLF{ct:Amid} | [G10a]3 SHa | Amidation | Free | Branched | Mix | a = D-alanine, Linked b/w Lys27 and Phe27 | 41 | Antimicrobial, Antiproliferative | 50 % Hemolysis at 10.46 ± 0.36 µM | Human | Dendrimeric Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLF-FLSGIVGMLDAKLF{ct:Amid} | Jeff-[G10a2 SHa conjugate | Amidation | Free | Linear | Mix | Jeffamine linker b/w Phe13 and Phe26 | 26 | Antimicrobial, Antiproliferative | 50 % Hemolysis at 1926 ± 242 µM | Human | Dendrimeric Analog Of Temporin-Sha | Triple Helical | Non-hemolytic | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLF{ct:Amid} | [G10a] SHa | Amidation | Free | Linear | Mix | a = D-alanine | 13 | Antimicrobial, Antiproliferative | 102.03 ± 6.18 % Hemolysis at 100 µM | Human | Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLFK-FLSGIVGMLDAKLF{ct:Amid} | [G10a]2 SHa | Amidation | Free | Linear | Mix | a = D-alanine, Linked b/w Phe26 and Lys40 and Lys41 and Phe39 | 27 | Antimicrobial, Antiproliferative | 100 % Hemolysis at 100 µM | Human | Dendrimeric Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLFKK-FLSGIVGMLDAKLF-FLSGIVGMLDAKLF{ct:Amid} | [G10a]3 SHa | Amidation | Free | Branched | Mix | a = D-alanine, Linked b/w Lys27 and Phe27 | 41 | Antimicrobial, Antiproliferative | 100 % Hemolysis at 100 µM | Human | Dendrimeric Analog Of Temporin-Sha | α-Helix | NA | ||
| 35740895 | 2022 | FLSGIVGMLA{d}KLF-FLSGIVGMLDAKLF{ct:Amid} | Jeff-[G10a2 SHa conjugate | Amidation | Free | Linear | Mix | a = D-alanine, Jeffamine linker b/w Phe13 and Phe26 | 26 | Antimicrobial, Antiproliferative | 24.01 ± 5.06 % Hemolysis at 100 µM | Human | Dendrimeric Analog Of Temporin-Sha | Triple Helical | Non-hemolytic | ||
| 35638842 | 2022 | KKLF{d}KKILKYL{ct:Amid}{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 11 | Antimicrobial | 3 ± 0.6 % Hemolysis at 50 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK({nnr:COC3H7})L{nt:Acet}{ct:Amid} | BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antimicrobial | 0 ± 0 % Hemolysis at 50 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | RINSAKDDAAGLQIAKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | flg15-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 7 ± 0.6 % Hemolysis at 50 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LRINSAKDDAAGLQIA{nt:Acet}{ct:OH} | BP475-flg15 | OH | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 1 ± 1.0 % Hemolysis at 50 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | FKLFKKILKVLKKLF{d}KKILKYL{ct:Amid} | BP13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 0.6 % Hemolysis at 50 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLFKLFKKILKVL{ct:Amid} | BP143-BP13 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 6.1 % Hemolysis at 50 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | VWNQPVRGFKVYEKKLF{d}KKILKYL{ct:Amid} | Pep13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 5 ± 0.5 % Hemolysis at 50 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLVWNQPVRGFKVYE{ct:OH} | BP143-Pep13 | OH | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 5 ± 1.9 % Hemolysis at 50 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | YGIHTHKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | PIP1-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 4 ± 0.4 % Hemolysis at 50 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LYGIHTH{nt:Acet}{ct:Amid} | BP475-PIP1 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 9 ± 1.0 % Hemolysis at 50 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYL{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 11 | Antimicrobial | 7 ± 2 % Hemolysis at 150 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{nnr:COC3H7}L{ct:Acet}{ct:Acet} | BP475 | Acetylation | Free | Linear | Mix | COC3H7 = butanoyl | 11 | Antimicrobial | 11 ± 5 % Hemolysis at 150 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | RINSAKDDAAGLQIAKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | flg15-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 28 ± 2.3 % Hemolysis at 150 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LRINSAKDDAAGLQIA{nt:Acet}{ct:OH} | BP475-flg15 | OH | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 0 ± 0.2 % Hemolysis at 150 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | FKLFKKILKVLKKLF{d}KKILKYL{ct:Amid} | BP13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 3.7 % Hemolysis at 150 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLFKLFKKILKVL{ct:Amid} | BP143-BP13 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 3.6 % Hemolysis at 150 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | VWNQPVRGFKVYEKKLF{d}KKILKYL{ct:Amid} | Pep13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 8 ± 0.3 % Hemolysis at 150 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLVWNQPVRGFKVYE{ct:OH} | BP143-Pep13 | OH | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 9 ± 0.4 % Hemolysis at 150 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | YGIHTHKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | PIP1-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 11 ± 0.5 % Hemolysis at 150 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LYGIHTH{nt:Acet}{ct:Amid} | BP475-PIP1 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 18 ± 1.4 % Hemolysis at 150 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYL{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 11 | Antimicrobial | 6 ± 0.3 % Hemolysis at 250 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antimicrobial | 0 ± 0 % Hemolysis at 250 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | RINSAKDDAAGLQIAKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | flg15-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 43 ± 2.7 % Hemolysis at 250 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LRINSAKDDAAGLQIA{nt:Acet}{ct:OH} | BP475-flg15 | OH | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 1 ± 0.3 % Hemolysis at 250 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | FKLFKKILKVLKKLF{d}KKILKYL{ct:Amid} | BP13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 3.2 % Hemolysis at 250 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLFKLFKKILKVL{ct:Amid} | BP143-BP13 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 7.1 % Hemolysis at 250 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | VWNQPVRGFKVYEKKLF{d}KKILKYL{ct:Amid} | Pep13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 10 ± 0.6 % Hemolysis at 250 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLVWNQPVRGFKVYE{ct:OH} | BP143-Pep13 | OH | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 16 ± 1.9 % Hemolysis at 250 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | YGIHTHKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | PIP1-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 18 ± 0.1 % Hemolysis at 250 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LYGIHTH{nt:Acet}{ct:Amid} | BP475-PIP1 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 26 ± 2.8 % Hemolysis at 250 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYL{ct:Amid} | BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 11 | Antimicrobial | 7 ± 0.3 % Hemolysis at 375 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 11 | Antimicrobial | 0 ± 0 % Hemolysis at 375 µM | Horse | Synthetic | NA | NA | ||
| 35638842 | 2022 | RINSAKDDAAGLQIAKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | flg15-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 46 ± 3.6 % Hemolysis at 375 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LRINSAKDDAAGLQIA{nt:Acet}{ct:OH} | BP475-flg15 | OH | Acetylation | Linear | Mix | COC3H7 = butanoyl | 26 | Antimicrobial | 1 ± 0.3 % Hemolysis at 375 µM | Horse | Synthetic; Flg15 Conjugates | NA | NA | ||
| 35638842 | 2022 | FKLFKKILKVLKKLF{d}KKILKYL{ct:Amid} | BP13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 10.6 % Hemolysis at 375 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLFKLFKKILKVL{ct:Amid} | BP143-BP13 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 22 | Antimicrobial | 100 ± 7.0 % Hemolysis at 375 µM | Horse | Synthetic; Bp13 Conjugates | NA | NA | ||
| 35638842 | 2022 | VWNQPVRGFKVYEKKLF{d}KKILKYL{ct:Amid} | Pep13-BP143 | Amidation | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 17 ± 0.4 % Hemolysis at 375 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKYLVWNQPVRGFKVYE{ct:OH} | BP143-Pep13 | OH | Free | Linear | Mix | lowercase letters correspond to D-amino acids | 24 | Antimicrobial | 29 ± 0.9 % Hemolysis at 375 µM | Horse | Synthetic; Pep13 Conjugates | NA | NA | ||
| 35638842 | 2022 | YGIHTHKKLF{d}KKILKK{conj:COC3H7}L{nt:Acet}{ct:Amid} | PIP1-BP475 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 24 ± 0.5 % Hemolysis at 375 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35638842 | 2022 | KKLF{d}KKILKK{conj:COC3H7}LYGIHTH{nt:Acet}{ct:Amid} | BP475-PIP1 | Amidation | Acetylation | Linear | Mix | COC3H7 = butanoyl | 17 | Antimicrobial | 39 ± 2.0 % Hemolysis at 375 µM | Horse | Synthetic; Pip1 Conjugates | NA | NA | ||
| 35847280 | 2022 | QR{d}W{d}GL{d}SL{d}APYK{d}NFR{d}R{d}L{d}S | ASU2056 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <1 % Hemolysis at 32 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35847280 | 2022 | QR{d}W{d}GL{d}SL{d}APYK{d}NFR{d}R{d}L{d}S | ASU2056 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <1 % Hemolysis at 64 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35847280 | 2022 | QR{d}W{d}GL{d}SL{d}APYK{d}NFR{d}R{d}L{d}S | ASU2056 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <1 % Hemolysis at 128 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35847280 | 2022 | VGR{d}W{d}SAR{d}YNFR{d}W{d}R{d}K{d}SGL{d} | ASU2060 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <0.1 % Hemolysis at 8 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35847280 | 2022 | VGR{d}W{d}SAR{d}YNFR{d}W{d}R{d}K{d}SGL{d} | ASU2060 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <0.1 % Hemolysis at 16 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35847280 | 2022 | VGR{d}W{d}SAR{d}YNFR{d}W{d}R{d}K{d}SGL{d} | ASU2060 | Free | Free | Linear | Mix | Lower-case letters signify D-amino acids | 17 | Antimicrobial | <0.1 % Hemolysis at 32 µM | Human | Synthetic | NA | Low hemolytic | ||
| 35700987 | 2022 | {nnr:DG}-K-W-W-{nnr:Orn}-N-{nnr:Nva}-{nnr:Aib}-R-W-W | DG-K-oLBF127 | Free | Free | Linear | Mix | Tyr(OMe) = Tyrosine (O-Methylated), Orn = Ornithine, Nva = Norvaline, Dpr = Dap (2,3-Diaminopropionic acid), Aib = Alpha-Amino isobutyric acid | 10 | Antifungal | Hemolysis at 25 µM | mouse | Synthetic; K-Olbf127 Analogs | α-Helix | NA | ||
| 35700987 | 2022 | K{d}-W{d}-W{d}-{nnr:orn}-N{d}-{nnr:nva}-{nnr:Aib}-R{d}-W{d}-W{d} | ki-oLBF127 | Free | Free | Linear | Mix | Tyr(OMe) = Tyrosine (O-Methylated), Orn = Ornithine, Nva = Norvaline, Dpr = Dap (2,3-Diaminopropionic acid), Aib = Alpha-Amino isobutyric acid, Lower-case letters signify D-amino acids | 10 | Antifungal | Hemolysis at 20 µM | mouse | Synthetic; K-Olbf127 Analogs | α-Helix | NA | ||
| 35700987 | 2022 | K{d}-W{d}-W{d}-R{d}-{nnr:Aib}-{nnr:nva}-N{d}-{nnr:orn}-W{d}-W{d} | kri-oLBF127 | Free | Free | Linear | Mix | Tyr(OMe) = Tyrosine (O-Methylated), Orn = Ornithine, Nva = Norvaline, Dpr = Dap (2,3-Diaminopropionic acid), Aib = Alpha-Amino isobutyric acid, Lower-case letters signify D-amino acids | 10 | Antifungal | Hemolysis at >200 µM | mouse | Synthetic; K-Olbf127 Analogs | α-Helix | NA | ||
| 35700987 | 2022 | K-W{d}-W{d}-{nnr:Orn}-N-{nnr:Nva}-{nnr:Aib}-R-W{d}-W{d} | kw-oLBF127 | Free | Free | Linear | Mix | Tyr(OMe) = Tyrosine (O-Methylated), Orn = Ornithine, Nva = Norvaline, Dpr = Dap (2,3-Diaminopropionic acid), Aib = Alpha-Amino isobutyric acid, Lower-case letters signify D-amino acids | 10 | Antifungal | Hemolysis at 80 µM | mouse | Synthetic; K-Olbf127 Analogs | α-Helix | NA | ||
| 35972429 | 2022 | RRRLCFVRP{d}KFVVCVRRP{d} | PLP-3 | Free | Free | Linear | Mix | None | 18 | Antimicrobial | 50 % Hemolysis at 48.5 mg/L | Human | Protegrin-1 (Pg-1) Analog | β-Hairpin | Non-hemolytic | ||
| 25561178 | 2015 | {nnr:x}ISQ{d}I{d}IST{d}A{nnr:X}I | Teixobactin | Free | Free | Linear | Mix | x = NmPhe(N-methylated phenylalanine), X = End (Enduracididine) | 11 | Anticancer, Antibacterial | No Hemolysis | Human | Eleftheria Terrae | NA | Non-hemolytic | ||
| 25485686 | 2015 | TR{d}SG{nnr:x}LR{d}EQ{d}W{d}IT | Lysocin E | Free | Free | Linear | Mix | x = D-N-Methylphenylalanine | 12 | Antibacterial, Antifungal | <1 % Hemolysis at 100μg/mL | Sheep | Lysobacter | NA | Non-hemolytic | ||
| 25485686 | 2015 | TR{d}SG{nnr:x}LR{d}EQ{d}W{d}IT | Lysocin E | Free | Free | Linear | Mix | x = D-N-Methylphenylalanine | 12 | Antibacterial, Antifungal | <1 % Hemolysis at 100μg/mL | Horse | Lysobacter | NA | Non-hemolytic | ||
| 8223491 | 1993 | I{nnr:l}GPVLGLVGSALGGLLKKI | Bombinin H4 | Free | Free | Linear | Mix | l = D-aILe(D-alloisoleucine) | 20 | Antibacterial, hemolytic, Antifungal, candidacidal, Antiparasitic | Hemolysis at 14.6μM | Human | Yellow-Bellied Toad, Bombina Variegata L, Europe | Helix | NA | ||
| 9022710 | 1993 | I{nnr:l}GPVLGMVGSALGGLLKKI | Bombinin H3 | Free | Free | Linear | Mix | l = D-alloisoleucine | 20 | Antibacterial, Hemolytic | Hemolytic at 15.7µM | Human | Toad, Bombina Variegata, Europe | NA | NA |