Hemolytik 2.0 - Browse by Function

Please wait...

Browsing by Function

Browse Results:

Filter by Year
From
Upto

ID	PMID	YEAR	Sequence	MAP	Name	C-ter MOD	N-ter MOD	Linear/Cyclic	Stereo-Chemistry	Modified	Length	Fuction	Activity	RBCs Source	Origin	Experimental structure	Non-Hemolytic
1643	16137634	2005	RQIKIWFQNRRMKWKK	RQIKIWFQNRRMKWKK{ct:Amid}	pAntp(43–58)	Amidation	Free	Linear	L	None	16	CPP	20.0±1.8% hemolysis at 50µM	Bovine	Penetratin (fragment of Antennapedia homeodomain)	NA	NA
1644	16137634	2005	GRKKRRQRRRPPQ	GRKKRRQRRRPPQ{ct:Amid}	pTAT(48–60)	Amidation	Free	Linear	L	None	13	CPP	11.2±1.5% hemolysis at 50µM	Bovine	Fragment of transcription factor coded by theTat protein (HIV virus)	NA	NA
1645	16137634	2005	LLIILRRRIRKQAHAHSK	LLIILRRRIRKQAHAHSK{ct:Amid}	pVEC(615–632)	Amidation	Free	Linear	L	None	18	CPP	18.1±0.3% hemolysis at 50µM	Bovine	Vascular endothelial cadherin protein (Murine)	NA	NA
1646	16137634	2005	KLALKLALKALKAALKLA	KLALKLALKALKAALKLA{ct:Amid}	MAP	Amidation	Free	Linear	L	None	18	CPP	20.9±1.8% hemolysis at 50µM	Bovine	Synthetic peptide	NA	NA
1647	16137634	2005	AGYLLGKINLKALAALAKKIL	AGYLLGKINLKALAALAKKIL{ct:Amid}	Transportan 10	Amidation	Free	Linear	L	None	21	CPP	29.0±4.9% hemolysis at 50µM	Bovine	Galanin and Mastoparan fragments	NA	NA
2700	22328546	2012	GIGAVLKVLTTGLPALISWIKRKRQQ	GIGAVLKVLTTGLPALISWIKRKRQQ	Melittin	Free	Free	Linear	L	None	26	CPP	>80% hemolytic at 25μM at pH 8	Human	Melittin (Apis mellifera)	NA	NA
2701	22328546	2012	GIGAVLKVLTTGLPALISWIKRKRQQ	GIGAVLKVLTTGLPALISWIKRKRQQ	Melittin	Free	Free	Linear	L	None	26	CPP	<60% hemolytic at 25μM at pH 6	Human	Melittin (Apis mellifera)	NA	NA
2702	22328546	2012	GIGAVLKVLTTGLPALISWI	GIGAVLKVLTTGLPALISWI	MT20	Free	Free	Linear	L	None	20	CPP	<80% hemolytic at 25μM at pH 8	Human	Truncated peptides of melittin	NA	NA
2703	22328546	2012	GIGAVLKVLTTGLPALISWI	GIGAVLKVLTTGLPALISWI	MT20	Free	Free	Linear	L	None	20	CPP	40% hemolytic at 25μM at pH 5	Human	Truncated peptides of melittin	NA	NA
2704	22328546	2012	GIGAILKVLATGLPTLISWIKNKRKQ	GIGAILKVLATGLPTLISWIKNKRKQ	Florae	Free	Free	Linear	L	None	26	CPP	<70% hemolytic at 25μM at pH 6	Human	Melittin analog	NA	NA
2705	22328546	2012	GIGAILKVLATGLPTLISWIKNKRKQ	GIGAILKVLATGLPTLISWIKNKRKQ	Florae	Free	Free	Linear	L	None	26	CPP	~80% hemolytic at 25μM at pH 8	Human	Melittin analog	NA	NA
2706	22328546	2012	GIGAILKVLATGLPTLISWI	GIGAILKVLATGLPTLISWI	FL20	Free	Free	Linear	L	None	20	CPP	<60% hemolytic at 25μM at pH 5	Human	Truncated peptides of florae (Apis florae)	NA	NA
2707	22328546	2012	GIGAILKVLATGLPTLISWI	GIGAILKVLATGLPTLISWI	FL20	Free	Free	Linear	L	None	20	CPP	~80% hemolytic at 25μM at pH 8	Human	Truncated peptides of florae (Apis florae)	NA	NA
2968	21956793	2011	LLIILRRRIRKQAHAHSK	LLIILRRRIRKQAHAHSK{ct:Amid}	pVEC	Amidation	Free	Linear	L	None	18	Antimicrobial and CPP	>10% hemolytic at 200μM	Human	Vascular endothelial-cadherin protein derivative analog (Murine)	NA	NA
2969	21956793	2011	LLIILRRRWRKQARARSK	LLIILRRRWRKQARARSK{ct:Amid}	pVEC-a1	Amidation	Free	Linear	L	None	18	Antimicrobial and CPP	>10% hemolytic at 200μM	Human	Vascular endothelial-cadherin protein derivative analog (Murine)	NA	NA
2970	21956793	2011	LLIILRRRWRKQAKAKSK	LLIILRRRWRKQAKAKSK{ct:Amid}	pVEC-a2	Amidation	Free	Linear	L	None	18	Antimicrobial and CPP	>10% hemolytic at 200μM	Human	Vascular endothelial-cadherin protein derivative analog (Murine)	NA	NA
2971	21956793	2011	LLIILRRRWRRQARARSR	LLIILRRRWRRQARARSR{ct:Amid}	pVEC-a3	Amidation	Free	Linear	L	None	18	Antimicrobial and CPP	>10% hemolytic at 94μM	Human	Vascular endothelial-cadherin protein derivative analog (Murine)	NA	NA
2972	21956793	2011	LLIILKKKWKKQAKAKSK	LLIILKKKWKKQAKAKSK{ct:Amid}	pVEC-a4	Amidation	Free	Linear	L	None	18	Antimicrobial and CPP	>10% hemolytic at 200μM	Human	Vascular endothelial-cadherin protein derivative analog (Murine)	NA	NA
3168	22965637	2013	ILGKLLSTAAGLLSNL	ILGKLLSTAAGLLSNL{ct:Amid}	Alyteserin-2a	Amidation	Free	Linear	L	None	16	CPP	LC50 =140μM	Human	Derived from skin secretions of Alytes obstetricans (alyteserin-2a)	α-helical	NA
3169	22965637	2013	ILKKLLSTAAGLLSNL	ILKKLLSTAAGLLSNL{ct:Amid}	G3K	Amidation	Free	Linear	L	None	16	CPP	LC50 =105μM	Human	Alyteserin-2a analog	NA	NA
3170	22965637	2013	ILGKLLKTAAGLLSNL	ILGKLLKTAAGLLSNL{ct:Amid}	S7K	Amidation	Free	Linear	L	None	16	CPP	LC50 =28μM	Human	Alyteserin-2a analog	NA	NA
3171	22965637	2013	ILGKLLkTAAGLLSNL	ILGKLLK{d}TAAGLLSNL{ct:Amid}	S7k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =105μM	Human	Alyteserin-2a analog	NA	NA
3172	22965637	2013	ILGKLLSTAAKLLSNL	ILGKLLSTAAKLLSNL{ct:Amid}	G11K	Amidation	Free	Linear	L	None	16	CPP	LC50 =24μM	Human	Alyteserin-2a analog	NA	NA
3173	22965637	2013	ILGKLLSTAAkLLSNL	ILGKLLSTAAK{d}LLSNL{ct:Amid}	G11k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =42μM	Human	Alyteserin-2a analog	NA	NA
3174	22965637	2013	ILGKLLSTAAGLLKNL	ILGKLLSTAAGLLKNL{ct:Amid}	S14K	Amidation	Free	Linear	L	None	16	CPP	LC50 =55μM	Human	Alyteserin-2a analog	NA	NA
3175	22965637	2013	ILGKLLSTAAGLLSKL	ILGKLLSTAAGLLSKL{ct:Amid}	N15K	Amidation	Free	Linear	L	None	16	CPP	LC50 =50μM	Human	Alyteserin-2a analog	NA	NA
3176	22965637	2013	ILGKLLSTAAGLLSkL	ILGKLLSTAAGLLSK{d}L{ct:Amid}	N15k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =310μM	Human	Alyteserin-2a analog	NA	NA
3177	22965637	2013	ILGKLLKTAAKLLSNL	ILGKLLKTAAKLLSNL{ct:Amid}	S7K,G11K	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =38μM	Human	Alyteserin-2a analog	NA	NA
3178	22965637	2013	ILGKLLkTAAkLLSNL	ILGKLLK{d}TAAK{d}LLSNL{ct:Amid}	S7k,G11k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =185μM	Human	Alyteserin-2a analog	NA	NA
3179	22965637	2013	ILGKLLSTAAKLLSKL	ILGKLLSTAAKLLSKL{ct:Amid}	G11K,N15K	Amidation	Free	Linear	L	None	16	CPP	LC50 =16μM	Human	Alyteserin-2a analog	NA	NA
3180	22965637	2013	ILGKLLSTAAkLLSKL	ILGKLLSTAAK{d}LLSKL{ct:Amid}	G11k,N15K	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =195μM	Human	Alyteserin-2a analog	NA	NA
3181	22965637	2013	ILGKLLSWAAGLLSNL	ILGKLLSWAAGLLSNL{ct:Amid}	T8W	Amidation	Free	Linear	L	None	16	CPP	LC50 =13μM	Human	Alyteserin-2a analog	NA	NA
3182	22965637	2013	ILGKLLSTWAGLLSNL	ILGKLLSTWAGLLSNL{ct:Amid}	A9W	Amidation	Free	Linear	L	None	16	CPP	LC50 =39μM	Human	Alyteserin-2a analog	NA	NA
3183	22965637	2013	ILGKLLSTAWGLLSNL	ILGKLLSTAWGLLSNL{ct:Amid}	A10W	Amidation	Free	Linear	L	None	16	CPP	LC50 =11μM	Human	Alyteserin-2a analog	NA	NA
3184	22965637	2013	ILGKLLSTAWkLLSNL	ILGKLLSTAWK{d}LLSNL{ct:Amid}	A10W,G11k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =21μM	Human	Alyteserin-2a analog	NA	NA
3185	22965637	2013	ILGKLLSTAWGLLSKL	ILGKLLSTAWGLLSKL{ct:Amid}	A10W,N15K	Amidation	Free	Linear	L	None	16	CPP	LC50 =6μM	Human	Alyteserin-2a analog	NA	NA
3186	22965637	2013	ILGKLLSTAWALLSkL	ILGKLLSTAWALLSK{d}L{ct:Amid}	A10W,N15k	Amidation	Free	Linear	Mix	None	16	CPP	LC50 =27μM	Human	Alyteserin-2a analog	NA	NA
3274	23776609	2013	RAGLQFPVGRLLR	RAGLQFPVGRLLR	BR1	Free	Free	Linear	L	None	13	CPP	Inactive	Human	buforin IIb	NA	Non-hemolytic
3275	23776609	2013	RAGLQFPVGRLLRRLLR	RAGLQFPVGRLLRRLLR	BR2	Free	Free	Linear	L	None	17	CPP	Inactive	Human	buforin IIb	NA	Non-hemolytic
3276	23776609	2013	RAGLQFPVGRLLRRLLRRLLR	RAGLQFPVGRLLRRLLRRLLR	BR3	Free	Free	Linear	L	None	21	CPP	5% hemolysis at 25μM	Human	buforin IIb	NA	NA
3277	23776609	2013	RAGLQFPVGRLLRRLLRRLLR	RAGLQFPVGRLLRRLLRRLLR	BR3	Free	Free	Linear	L	None	21	CPP	34.3% hemolysis at 200μM	Human	buforin IIb	NA	NA
3278	23776609	2013	RKKRRQRRR	RKKRRQRRR	Tat (49–57)	Free	Free	Linear	L	None	9	CPP	Inactive	Human	buforin IIb	NA	Non-hemolytic
9139	29411917	2018	aza-β3Lys-K-aza-β3-1Nal-K-aza-β3-1Nal-L	aza-β3Lys-K-{nnr:aza-β3-1Nal}-K-{nnr:aza-β3-1Nal}-L{cyc:N-C}	ACPP20	Free	Free	Cyclic	L	aza-β3-Lys = aza-β3-Lysine, aza-β3-1Nal = aza-β3-1-Naphthylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	1.5 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	Low hemolytic
9140	29411917	2018	aza-β3Lys-K-aza-β3-2Nal-L-aza-β3-2Nal-L	aza-β3Lys-K-{nnr:aza-β3-2Nal}-L-{nnr:aza-β3-2Nal}-L{cyc:N-C}	ACPP21	Free	Free	Cyclic	L	aza-β3-Lys = aza-β3-Lysine, aza-β3-2Nal = aza-β3-2-Naphthylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	8 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	NA
9141	29411917	2018	aza-β3Lys-K-aza-β3-1Nal-L-aza-β3-4Fluo-1Nal-L	aza-β3Lys-K-{nnr:aza-β3-1Nal}-L-{nnr:aza-β3-4Fluo-1Nal}-L{cyc:N-C}	ACPP22	Free	Free	Cyclic	L	aza-β3-Leu = aza-β3-Leucine, aza-β3-1Nal = aza-β3-1-Naphthylalanine, aza-β3-4Fluo-1Nal = aza-β3-4Fluoro-1-Nahphtylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	5 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	Low hemolytic
9142	29411917	2018	K-aza-β3Lys-L-aza-β3-1Nal-aza-β3Leu-aza-β3-1Nal	K-aza-β3Lys-L-{nnr:aza-β3-1Nal}-aza-β3Leu-{nnr:aza-β3-1Nal}{cyc:N-C}	ACPP23	Free	Free	Cyclic	L	aza-β3-Lys = aza-β3-Lysine, aza-β3-1Nal = aza-β3-1-Naphthylalanine, aza-β3-Leu = aza-β3-Leucine, aza-β3-1Nal = aza-β3-1-Naphthylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	6 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	NA
9143	29411917	2018	aza-β3Arg-R-aza-β3-1Nal-L-aza-β3-1Nal-L	aza-β3Arg-R-{nnr:aza-β3-1Nal}-L-{nnr:aza-β3-1Nal}-L{cyc:N-C}	ACPP24	Free	Free	Cyclic	L	aza-β3-Arg = aza-β3-Arginine, aza-β3-1Nal = aza-β3-1-Naphthylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	12 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	NA
9144	29411917	2018	aza-β3Lys-R-aza-β3-2Nal-F-aza-β3-2Nal-F	aza-β3Lys-R-{nnr:aza-β3-2Nal}-F-{nnr:aza-β3-2Nal}-F{cyc:N-C}	ACPP25	Free	Free	Cyclic	L	aza-β3-Lys = aza-β3-Lysine, aza-β3-2Nal = aza-β3-2-Naphthylalanine	6	Antimicrobial cyclic pseudopeptides (ACPPs)	50 % Hemolysis at 100 µM	Sheep	Synthesis Of Mixed Aza-Β3-Pseudopeptides	NA	NA
10940	32024261	2020	KARKKKLNKKGRKMAGRKRGRPKK	KARKKKLNKKGRKMAGRKRGRPKK	Dot1l	Free	Free	Linear	L	None	24	CPPs (Cell-penetrating peptides)	<0.5 % Hemolysis at 10 μM	Human	Human Gene Dot1L	α-Helical	Non-hemolytic
10941	32024261	2020	KARKKKLNKKGRKMAGRKRGRPKK	KARKKKLNKKGRKMAGRKRGRPKK	Dot1l	Free	Free	Linear	L	None	24	CPPs (Cell-penetrating peptides)	<0.5 % Hemolysis at 7.5 μM	Human	Human Gene Dot1L	α-Helical	Non-hemolytic