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| ID | PMID | YEAR | Sequence | MAP | Name | C-ter MOD | N-ter MOD | Linear/Cyclic | Stereo-Chemistry | Modified | Length | Nature | Activity | RBCs Source | Origin | Experimental structure | Non-Hemolytic |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 1 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 100 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 2 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 9 | Antibacterial | 38.7 ± 5.4 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl){nt:H}{ct:Amid} | Peptoid - 3 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 100 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3){nt:H}{ct:Amid} | Peptoid - 4 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 100 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF){nt:H}{ct:Amid} | Peptoid - 5 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 100 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 6 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 13 | Antibacterial | 48.1 ± 3 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 7 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 10 | Antibacterial | 9.8 ± 0.8 % Hemolysis at 200 mM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 1 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 10 % Hemolysis at 9.1 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 2 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 9 | Antibacterial | 10 % Hemolysis at 119.5 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl){nt:H}{ct:Amid} | Peptoid - 3 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 10 % Hemolysis at <6.25 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3){nt:H}{ct:Amid} | Peptoid - 4 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 10 % Hemolysis at <6.25 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF){nt:H}{ct:Amid} | Peptoid - 5 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 10 % Hemolysis at <6.25 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 6 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 13 | Antibacterial | 10 % Hemolysis at 19.5 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 7 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 10 | Antibacterial | 10 % Hemolysis at >200 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 1 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 50 % Hemolysis at 63.4 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}{nt:H}{ct:Amid} | Peptoid - 2 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 9 | Antibacterial | 50 % Hemolysis at 1>200 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl)-{nnr:Nlys}-{nnr:Nspe}(pCl)-{nnr:Nspe}(pCl){nt:H}{ct:Amid} | Peptoid - 3 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 50 % Hemolysis at 10.4 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3)-{nnr:Nlys}-{nnr:Nspe}(pCH3)-{nnr:Nspe}(pCH3){nt:H}{ct:Amid} | Peptoid - 4 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 50 % Hemolysis at 8.3 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF)-{nnr:Nlys}-{nnr:Nspe}(pF)-{nnr:Nspe}(pF){nt:H}{ct:Amid} | Peptoid - 5 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 12 | Antibacterial | 50 % Hemolysis at <6.25 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 6 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 13 | Antibacterial | 50 % Hemolysis at >200 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 29198866 | 2018 | {nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}-{nnr:Nspe}-{nnr:Nspe}-{nnr:Nlys}{nt:H}{ct:Amid} | Peptoid - 7 | Amidation | H | Linear | NA | Nlys = N-(4-aminobutyl)glycine, Nspe = N-(S)-(1-phenylethyl)glycine | 10 | Antibacterial | 50 % Hemolysis at >200 μM | Rat | Synthetic Peptoid | α-Helical | NA | ||
| 34070683 | 2021 | {nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}{nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}-{nnr:hArg}-{nnr:βNPhe}{nt:Acet}{ct:Amid} | Subclass I-1 | Amidation | Acetylation | Linear | NA | hArg = homoarginine, βNPhe = N-benzyl-β-alanine | 16 | Antibacterial | 6.1 % Hemolysis at 400 µg/mL | Human | Synthetic Peptide/Β-Peptoid Hybrids | NA | Low hemolytic | ||
| 34070683 | 2021 | {nnr:hArg}-{nnr:βNsce}-{nnr:hArg}-{nnr:βNsce}-{nnr:hArg}-{nnr:βNsce}-{nnr:hArg}-{nnr:βNsce}-{nnr:hArg}-{nnr:βNsce}-{nnr:hArg}-{nnr:βNsce}{nt:Acet}{ct:Amid} | Subclass I-2 | Amidation | Acetylation | Linear | NA | hArg = homoarginine, βNsce = N-(S)-1-cyclohexylethyl-β-alanine | 12 | Antibacterial | 98.4 % Hemolysis at 400 µg/mL | Human | Synthetic Peptide/Β-Peptoid Hybrids | NA | NA | ||
| 36279986 | 2022 | {nnr:β2,2-Ac6c}-{nnr:Gpn}-{nnr:β2,2-Ac6c}-{nnr:Gpn}-{nnr:β2,2-Ac6c}-{nnr:Gpn}{nt:H}{ct:OMe} | BG6 | OMe | H | Linear | NA | β2,2-Ac6c = 1-aminomethylcyclohexane carboxylic acid, Gpn = 2-(1-(aminomethyl)cyclohexyl)acetic acid | 6 | Anticancer, Anti-migratory and Anti-invasive | 8.05 % Hemolysis at 30 µM/ml | Human | Short Hybrid Synthetic Peptide | NA | Low hemolytic |