Details of CPPsite entry with Sequence rrrrrr |
Primary information | |
---|---|
PEPTIDE SEQUENCE | rrrrrr |
CPPsite ID | 1040, |
PEPTIDE NAME | D-R6 |
CHIRALITY | D |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Probably cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | High (comparable to Tat (49-57) and higher than R6 |
PROPOSED UPTAKE MECHANISM | Probably non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | Jurkat |
CARGO | Fluorophore (fluorescein) |
PMID | 11087855 |
PATENT | US 6593292 |
Tertiary Structure (Technique) | 1040 (PEPstrMOD), |