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Details of CPPsite entry with Sequence WKCRRQCFRVLHHWN
Primary information
PEPTIDE SEQUENCEWKCRRQCFRVLHHWN
CPPsite ID 2736, 1270,
PEPTIDE NAME45, JF06
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYNA, Amphipathic
SUB CELLULAR LOCALIZATIONNA, Unknown
N-TERMINAL MODIFICATIONNA, Conjugation with fluorescein
C-TERMINAL MODIFICATIONNA, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYNA, Similar or greater than TAT in CHO cells
PROPOSED UPTAKE MECHANISMNA, Unknown
INVITRO/INVIVOIn vitro and in vivo, In vitro
CELL LINEMany Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF, HeLa, Jurkat and CHO
In VIVO MODELNOD-SCID mice model of xenograft human tumour cells, NA
CARGOFluorophore (FITC), Fluorophore (fluorescein)
PMID22805558, 19956900
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2736 (PEPstrMOD), 1270 (PEPstrMOD),