Welcome to Sequence Card of Peptide


Details of CPPsite entry with Sequence TRRQRTRRARRNRGC
Primary information
PEPTIDE SEQUENCETRRQRTRRARRNRGC
CPPsite ID 1397, 1835,
PEPTIDE NAMEHTLV -II Rex(4-16), HTLV-II Rex (4-16)
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Protein derived
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus, Unknown
N-TERMINAL MODIFICATIONFree, Free
C-TERMINAL MODIFICATIONConjugation with fluorescein by C-terminal Gly Cys amide, Conjugation with Alexa 488 at glycyl cysteine sequence
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYComparable with that of the Tat-(48-60) peptide, Less than Tat
PROPOSED UPTAKE MECHANISMNon-endocytic pathway, Unknown
INVITRO/INVIVOIn vitro, In vitro
CELL LINERAW 264.7, CHO-K1, HeLa and Jurkat
In VIVO MODELNA, NA
CARGOFluorophore (fluorescein), Fluorophore (Alexa-488)
PMID11084031, 19707187
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		1397 (PEPstrMOD), 1835 (PEPstrMOD),