Details of CPPsite entry with Sequence RXRXRXRXRXRXRXRXB |
Primary information | |
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PEPTIDE SEQUENCE | RXRXRXRXRXRXRXRXB |
CPPsite ID | 2605, 2606, 2607, |
PEPTIDE NAME | (RX)8B, (RX)8B, (RX)8B |
CHIRALITY | Modified, Modified, Modified |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Synthetic, Synthetic, Synthetic |
CATEGORY | Cationic, Cationic, Cationic |
SUB CELLULAR LOCALIZATION | NA, NA, NA |
N-TERMINAL MODIFICATION | NA, NA, NA |
C-TERMINAL MODIFICATION | NA, NA, NA |
CHEMICAL MODIFICATION | X, 6-aminohexanoic acid (Ahx) and B, Beta-Alanine, X, 6-aminohexanoic acid (Ahx) and B, Beta-Alanine, X, 6-aminohexanoic acid (Ahx) and B, Beta-Alanine |
UPTAKE EFFICIENCY | NA, NA, NA |
PROPOSED UPTAKE MECHANISM | NA, NA, NA |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | MCF7 cells, MCF7 cells, MCF7 cells |
In VIVO MODEL | NA, NA, NA |
CARGO | Nucleic acid [PPMOs targeting translation initiation site of p53 mRNA (M1)], Nucleic acid [PPMOs targeting splice acceptor site of exon 10 (E10SA)], Nucleic acid [PPMOs targeting the coding region within exon 10 |
PMID | 21765469, 21765469, 21765469 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | Not Predicted), Not Predicted), Not Predicted), |