Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence RXRRXRRXRRXR |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | RXRRXRRXRRXR |
| CPPsite ID | 2482, 2483, 2484, 2485, 2486, 2708, |
| PEPTIDE NAME | Peptide I, Peptide II, Peptide III, Peptide IV, Peptide V, (R-Ahx-R)4_amide_CF (I) |
| CHIRALITY | Modified, Modified, Modified, Modified, Modified, Modified |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear, Linear, Linear |
| SOURCE | Synthetic, Synthetic, Synthetic, Synthetic, Synthetic, Synthetic |
| CATEGORY | NA, NA, NA, NA, NA, NA |
| SUB CELLULAR LOCALIZATION | Cytoplasm, Cytoplasm, Cytoplasm, Cytoplasm, Cytoplasm, Cytosol and Nucleus |
| N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein, Conjugation with 5(6)-Carboxyfluorescein, Conjugation with 5(6)-Carboxyfluorescein, Conjugation with 5(6)-Carboxyfluorescein, Conjugation with 5(6)-Carboxyfluorescein, NA |
| C-TERMINAL MODIFICATION | Amidation, Amidation, Amidation, Amidation, Amidation, NA |
| CHEMICAL MODIFICATION | X, aeLP, aminoethylpropyl, X, aeDP, aminoethylpropyl, X, apLP, aminopropylpropyl, X, apDP, aminopropylpropyl, X, 6-aminohexanoic acid (Ahx), Ahx, 6-aminohexanoic acid |
| UPTAKE EFFICIENCY | At 37 C peptide showed enhanced uptake in almost all cells compared to control peptide V, At 37 C peptide showed enhanced uptake in almost all cells compared to control peptide V, At 37 C peptide showed enhanced uptake in almost all cells compared to control peptide V, At 37 C peptide showed enhanced uptake in almost all cells compared to control peptide V and showed the best cellular uptake results, Used as control peptide for uptake process, NA |
| PROPOSED UPTAKE MECHANISM | NA, NA, NA, NA, NA, Energy dependent process |
| INVITRO/INVIVO | In vitro, In vitro, In vitro, In vitro, In vitro, In vitro |
| CELL LINE | CHO-K1, CHO-K1, CHO-K1, CHO-K1, CHO-K1, CHO-K1 |
| In VIVO MODEL | NA, NA, NA, NA, NA, NA |
| CARGO | Fluorophore (5/6-carboxyfluorescein), Fluorophore (5/6-carboxyfluorescein), Fluorophore (5/6-carboxyfluorescein), Fluorophore (5/6-carboxyfluorescein), Fluorophore (5/6-carboxyfluorescein), Nucleic acid (plasmid DNA) |
| PMID | 25096299, 25096299, 25096299, 25096299, 25096299, 22509923 |
| PATENT | Unknown, Unknown, Unknown, Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | Not Predicted), Not Predicted), Not Predicted), Not Predicted), Not Predicted), Not Predicted), |