Details of CPPsite entry with Sequence RVIRVWFQNKRCKDKK |
Primary information | |
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PEPTIDE SEQUENCE | RVIRVWFQNKRCKDKK |
CPPsite ID | 1491, 1737, |
PEPTIDE NAME | pISL, (SEQ ID NO: 29) |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Protein derived, Synthetic |
CATEGORY | Amphipathic, Unknown |
SUB CELLULAR LOCALIZATION | Cytoplasm and nucleus, Unknown |
N-TERMINAL MODIFICATION | Biotinylation, NA |
C-TERMINAL MODIFICATION | Amidation, NA |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | Comparable to penetratin, Unknown |
PROPOSED UPTAKE MECHANISM | Non-endocytic pathway, Unknown |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | Human bowes melanoma cells, 9 L/LacZ cells |
In VIVO MODEL | NA, NA |
CARGO | Biotin, Nucleic acid (siRNA) |
PMID | 11716681 |
PATENT | Unknown, US 20060035815 |
Tertiary Structure (Technique) | 1491 (PEPstrMOD), 1737 (PEPstrMOD), |