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Details of CPPsite entry with Sequence RVIRVWFQNKRCKDKK
Primary information
PEPTIDE SEQUENCERVIRVWFQNKRCKDKK
CPPsite ID 1491, 1737,
PEPTIDE NAMEpISL, (SEQ ID NO: 29)
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Synthetic
CATEGORYAmphipathic, Unknown
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus, Unknown
N-TERMINAL MODIFICATIONBiotinylation, NA
C-TERMINAL MODIFICATIONAmidation, NA
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYComparable to penetratin, Unknown
PROPOSED UPTAKE MECHANISMNon-endocytic pathway, Unknown
INVITRO/INVIVOIn vitro, In vitro
CELL LINEHuman bowes melanoma cells, 9 L/LacZ cells
In VIVO MODELNA, NA
CARGOBiotin, Nucleic acid (siRNA)
PMID11716681
PATENTUnknown, US 20060035815
Tertiary Structure
(Technique)
1491 (PEPstrMOD), 1737 (PEPstrMOD),